Protagonist Therapeutics, Inc. (PTGX)

NASDAQ: PTGX · Real-Time Price · USD

144.88

+1.15 (0.80%)

Oct 12, 2026, 4:00 PM EDT - Market closed

Protagonist Therapeutics Ratios and Metrics

Market cap in millions USD. Fiscal year is January - December.

Millions USD. Fiscal year is Jan - Dec.

Total Valuation

Fiscal Year	Current	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Oct '26 Oct 12, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Market Capitalization	9,375	5,460	2,300	1,323	537	1,632
Market Cap Growth	130.77%	137.35%	73.94%	146.40%	-67.12%	88.22%
Enterprise Value	8,535	4,792	1,728	1,002	274	1,286
Last Close Price	144.88	87.34	38.60	22.93	10.91	34.20

Price Ratios

Fiscal Year	Current	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Oct '26 Oct 12, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
PE Ratio	118.64	-	8.36	-	-	-
Forward PE	76.00	59.76	36.33	-	-	-
PS Ratio	33.25	118.66	5.30	22.04	20.19	59.67
PB Ratio	11.13	8.88	3.41	3.93	2.49	5.44
P/TBV Ratio	11.14	8.88	3.41	3.93	2.49	5.44
P/FCF Ratio	71.79	97.36	12.59	-	-	-
P/OCF Ratio	71.46	94.68	12.49	-	-	-

EV Ratios

Fiscal Year	Current	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Oct '26 Oct 12, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
EV/Sales Ratio	30.27	104.14	3.98	16.69	10.29	47.01
EV/EBITDA Ratio	142.52	-	6.81	-	-	-
EV/EBIT Ratio	146.29	-	6.84	-	-	-
EV/FCF Ratio	65.36	85.45	9.45	-	-	-

Financial Efficiency

Fiscal Year	Current	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Oct '26 Oct 12, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Debt / Equity Ratio	0.01	0.02	0.02	0.00	0.02	0.02
Debt / EBITDA Ratio	0.15	-	0.04	-	-	-
Debt / FCF Ratio	0.07	0.18	0.06	-	-	-
Net Debt / Equity Ratio	-1.00	-1.03	-0.81	-1.01	-1.08	-1.07
Net Debt / EBITDA Ratio	-14.03	4.05	-2.16	3.67	1.79	2.57
Net Debt / FCF Ratio	-6.43	-11.33	-3.00	4.81	2.15	2.95
Asset Turnover	0.35	0.07	0.79	0.20	0.09	0.08
Quick Ratio	21.58	12.59	12.39	16.54	7.61	7.55
Current Ratio	21.71	12.71	12.48	16.71	7.80	7.74
Return on Equity (ROE)	10.98%	-20.18%	54.39%	-28.59%	-49.41%	-43.32%
Return on Assets (ROA)	4.55%	-13.99%	28.66%	-19.32%	-27.57%	-23.40%
Return on Invested Capital (ROIC)	61.79%	-97.34%	189.05%	-	-	-
Return on Capital Employed (ROCE)	6.90%	-25.40%	36.30%	-27.80%	-60.60%	-41.40%

Yields

Fiscal Year	Current	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Oct '26 Oct 12, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Earnings Yield	0.88%	-2.38%	11.96%	-5.97%	-23.73%	-7.69%
FCF Yield	1.39%	1.03%	7.95%	-5.36%	-20.29%	-6.68%
Buyback Yield / Dilution	-4.05%	2.31%	-14.65%	-15.74%	-5.87%	-34.67%

SEC Filings: 10-K · 10-Q