ALPS Medical Breakthroughs ETF (SBIO)

SBIO Holdings Information

SBIO is an equity ETF with a total of 106 individual holdings. The top holdings are Rhythm Pharmaceuticals stock at 3.84%, Axsome Therapeutics at 3.50%, Avidity Biosciences at 3.28%, Nuvalent at 2.98%, and Merus at 2.87%.

• Total Holdings: 106
• Top 10 Percentage: 29.09%
• Asset Class: Equity
• ETF Category: Health
• Assets: 81.65M
• PE Ratio: n/a

Top 25 Holdings

As of Aug 31, 2025

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No.	Symbol	Name	% Weight	Shares
1	RYTM	Rhythm Pharmaceuticals, Inc.	3.84%	30,166
2	AXSM	Axsome Therapeutics, Inc.	3.50%	23,382
3	RNA	Avidity Biosciences, Inc.	3.28%	57,055
4	NUVL	Nuvalent, Inc.	2.98%	31,488
5	MRUS	Merus N.V.	2.87%	35,298
6	ALKS	Alkermes plc	2.79%	78,002
7	ACAD	ACADIA Pharmaceuticals Inc.	2.54%	79,186
8	KRYS	Krystal Biotech, Inc.	2.50%	13,707
9	CYTK	Cytokinetics, Incorporated	2.47%	56,589
10	PCVX	Vaxcyte, Inc.	2.32%	61,086
11	PTCT	PTC Therapeutics, Inc.	2.28%	37,470
12	ACLX	Arcellx, Inc.	2.24%	26,120
13	ZLAB	Zai Lab Limited	2.18%	53,349
14	AKRO	Akero Therapeutics, Inc.	2.18%	37,752
15	MTSR	Metsera, Inc.	2.17%	49,724
16	PTGX	Protagonist Therapeutics, Inc.	2.14%	29,413
17	MIRM	Mirum Pharmaceuticals, Inc.	2.14%	23,460
18	MLTX	MoonLake Immunotherapeutics	2.07%	30,091
19	APLS	Apellis Pharmaceuticals, Inc.	2.02%	59,454
20	ARWR	Arrowhead Pharmaceuticals, Inc.	1.78%	65,359
21	VKTX	Viking Therapeutics, Inc.	1.78%	53,206
22	XENE	Xenon Pharmaceuticals Inc.	1.74%	36,310
23	CRNX	Crinetics Pharmaceuticals, Inc.	1.70%	44,324
24	NAMS	NewAmsterdam Pharma Company N.V.	1.58%	53,128
25	TARS	Tarsus Pharmaceuticals, Inc.	1.44%	19,896

As of Aug 31, 2025

Showing 25 of 106 holdings

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