Spyre Therapeutics, Inc. (SYRE)

NASDAQ: SYRE · Real-Time Price · USD
28.70
+1.48 (5.44%)
Oct 11, 2024, 4:00 PM EDT - Market closed
5.44%
Market Cap 1.46B
Revenue (ttm) n/a
Net Income (ttm) -185.98M
Shares Out 50.92M
EPS (ttm) -7.31
PE Ratio n/a
Forward PE n/a
Dividend n/a
Ex-Dividend Date n/a
Volume 222,415
Open 27.21
Previous Close 27.22
Day's Range 27.15 - 28.96
52-Week Range 8.43 - 47.97
Beta 2.93
Analysts Strong Buy
Price Target 43.33 (+50.98%)
Earnings Date Nov 7, 2024

About SYRE

Spyre Therapeutics, Inc., a preclinical stage biotechnology company, focuses on developing therapeutics for patients living with inflammatory bowel disease (IBD). It develops SPY001, a human monoclonal immunoglobulin G1 antibody designed to bind selectively to the α4β7 integrin being developed for the treatment of IBD (ulcerative colitis and Crohn’s disease). The company is also developing SPY002, a human monoclonal antibody (mAb)candidates designed to bind to tumor necrosis factor-like ligand 1A; and SPY120, a combination of SPY001 (anti-α4β7)... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Apr 7, 2016
Employees 30
Stock Exchange NASDAQ
Ticker Symbol SYRE
Full Company Profile

Financial Performance

In 2023, Spyre Therapeutics's revenue was $886,000, a decrease of -61.96% compared to the previous year's $2.33 million. Losses were -$338.79 million, 304.2% more than in 2022.

Financial Statements

Analyst Forecast

According to 8 analysts, the average rating for SYRE stock is "Strong Buy." The 12-month stock price forecast is $43.33, which is an increase of 50.98% from the latest price.

Price Target
$43.33
(50.98% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Spyre Therapeutics Announces Grants of Inducement Awards

WALTHAM, Mass. , Oct. 4, 2024 /PRNewswire/ -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the "Company" or "Spyre"), a clinical-stage biotechnology company utilizing best-in-class antibody engineering, r...

9 days ago - PRNewsWire

Spyre: Extended Half-Life Tech To Become Differentiating Factor For IBD Targeting

Spyre Therapeutics, Inc. interim data from the phase 1 study, using SPY001 in healthy volunteers, is expected by the end of 2024. SPY001 is an a4b7 inhibitor being developed to target IBD like Crohn's...

12 days ago - Seeking Alpha

Spyre Therapeutics Appoints Dr. Sheldon Sloan as Chief Medical Officer

WALTHAM, Mass. , Oct. 1, 2024 /PRNewswire/ -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the "Company" or "Spyre"), a clinical-stage biotechnology company utilizing best-in-class antibody engineering, r...

12 days ago - PRNewsWire

Spyre Therapeutics to Participate in Upcoming Investor Conference

WALTHAM, Mass. , Sept. 10, 2024 /PRNewswire/ -- Spyre Therapeutics, Inc. (NASDAQ: SYRE), a clinical-stage biotechnology company utilizing best-in-class antibody engineering, rational therapeutic combi...

4 weeks ago - PRNewsWire

Spyre Therapeutics Reports Second Quarter 2024 Financial Results and Provides Corporate Update

Initiated dosing in Phase 1 trial of SPY001, an anti-α4β7 antibody engineered for infrequent, subcutaneous maintenance dosing, with interim proof-of-concept data on track for year-end 2024 SPY002, an ...

2 months ago - PRNewsWire

Spyre Therapeutics Announces First Participants Dosed in Phase 1 Trial of SPY001, its Novel Half-life Extended anti-α4β7 Antibody, for the Treatment of Inflammatory Bowel Disease

Preclinical data for SPY001 demonstrate the potential for improved dosing over standard of care, including the potential for dosing every eight or twelve weeks compared to dosing every two weeks for s...

4 months ago - PRNewsWire

Spyre Therapeutics to Participate in the Jefferies Global Healthcare Conference

WALTHAM, Mass. , May 29, 2024 /PRNewswire/ -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the "Company" or "Spyre"), a development-stage biotechnology company advancing best-in-class antibody engineering...

4 months ago - PRNewsWire

Spyre Therapeutics Appoints Accomplished Biopharma Leader Dr. Sandra Milligan to its Board of Directors

WALTHAM, Mass. , May 15, 2024 /PRNewswire/ -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the "Company" or "Spyre"), a development-stage biotechnology company advancing best-in-class antibody engineering...

5 months ago - PRNewsWire

Spyre Therapeutics Reports First Quarter 2024 Financial Results and Provides Corporate Update

SPY001, an anti-α4β7 antibody engineered for infrequent, subcutaneous dosing successfully completed a 28-day GLP toxicity study and remains on track to begin first-in-human studies in the second quart...

5 months ago - PRNewsWire

Spyre Therapeutics Announces $180 Million Private Placement

WALTHAM, Mass. , March 18, 2024 /PRNewswire/ -- Spyre Therapeutics, Inc. ("Spyre" or the "Company") (NASDAQ: SYRE), a biotechnology company advancing a pipeline of investigational antibody therapeutic...

7 months ago - PRNewsWire

Spyre Therapeutics Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Corporate Update

Announced corporate name change to Spyre Therapeutics; appointment of Cameron Turtle, DPhil, as Chief Executive Officer; and began trading on Nasdaq under the symbol "SYRE" SPY001, an anti-α4β7 antibo...

8 months ago - PRNewsWire

Spyre Therapeutics to Participate in the 44th Annual TD Cowen Health Care Conference

WALTHAM, Mass. , Feb. 26, 2024 /PRNewswire/ -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the "Company" or "Spyre"), a development-stage biotechnology company advancing best-in-class antibody engineerin...

8 months ago - PRNewsWire

Spyre Therapeutics Announces Three Abstracts Accepted for Presentation at the 19th Annual Congress of the European Crohn's and Colitis Organisation

WALTHAM, Mass. , Feb. 8, 2024 /PRNewswire/ -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the "Company" or "Spyre"), a development-stage biotechnology company advancing best-in-class antibody engineering...

8 months ago - PRNewsWire

Spyre Therapeutics Appoints Accomplished Biopharma and IBD Leader Mark C. McKenna, Former Chairman, President, and CEO of Prometheus Biosciences, to its Board of Directors

WALTHAM, Mass. , Feb. 5, 2024 /PRNewswire/ -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the "Company" or "Spyre"), a development-stage biotechnology company advancing best-in-class antibody engineering...

8 months ago - PRNewsWire

Spyre Therapeutics to Present at Upcoming Investor Conference

WALTHAM, Mass. , Nov. 28, 2023 /PRNewswire/ -- Spyre Therapeutics, Inc. ("Spyre") (NASDAQ: SYRE), a biotechnology company advancing a pipeline of antibody therapeutics with the potential to transform ...

11 months ago - PRNewsWire

Aeglea BioTherapeutics Announces Name Change to Spyre Therapeutics, Appoints CEO and Additional Directors, and Expands Leadership Team to Develop Next-Generation Therapeutic Combinations for the Treatment of IBD

Company will begin trading on Nasdaq under trading symbol "SYRE" effective November 28, 2023 Biotechnology leader Cameron Turtle, DPhil, appointed as Chief Executive Officer and Member of the Board of...

11 months ago - PRNewsWire

Aeglea BioTherapeutics Announces Grants of Inducement Awards

WALTHAM, Mass. , Nov. 22, 2023 /PRNewswire/ -- Aeglea BioTherapeutics, Inc. ("Aeglea") (NASDAQ: AGLE), a biotechnology company advancing a pipeline of antibody therapeutics with the potential to trans...

11 months ago - PRNewsWire

Aeglea BioTherapeutics Reports Third Quarter 2023 Financial Results and Provides Corporate Update

Continued progress across the Company's potentially best-in-class inflammatory bowel disease (IBD) portfolio SPY001, a half-life extended anti-α4β7 antibody, is on track for an expected IND filing in ...

1 year ago - PRNewsWire

Aeglea BioTherapeutics to Participate in Upcoming November Investor Conferences

WALTHAM, Mass. , Oct. 30, 2023 /PRNewswire/ -- Aeglea BioTherapeutics, Inc. ("Aeglea") (Nasdaq: AGLE), a biotechnology company advancing a pipeline of antibody therapeutics with the potential to trans...

1 year ago - PRNewsWire

Aeglea BioTherapeutics to Participate in Upcoming September Conference

WALTHAM, Mass. , Sept. 14, 2023 /PRNewswire/ -- Aeglea BioTherapeutics, Inc. ("Aeglea") (Nasdaq: AGLE), a biotechnology company advancing a pipeline of antibody therapeutics with the potential to tran...

1 year ago - PRNewsWire

Aeglea BioTherapeutics Announces Reverse Stock Split

WALTHAM, Mass. , Sept. 7, 2023 /PRNewswire/ -- Aeglea BioTherapeutics, Inc. ("Aeglea") (Nasdaq: AGLE), a biotechnology company advancing a pipeline of antibody therapeutics with the potential to trans...

1 year ago - PRNewsWire

Aeglea BioTherapeutics Expands Executive Leadership Team with Appointment of Industry Veterans Scott Burrows and Heidy Abreu King-Jones

Scott Burrows, former Arcutis Biotherapeutics CFO, assumes role as Chief Financial Officer  Heidy Abreu King-Jones, former Provention Bio CLO & Corporate Secretary, assumes role as Chief Legal Officer...

Other symbols: ARQT
1 year ago - PRNewsWire

Aeglea BioTherapeutics Reports Second Quarter 2023 Financial Results

Acquisition of Spyre's assets and concurrent oversubscribed $210.0 million private investment positions the company to advance a potentially best-in-class inflammatory bowel disease (IBD) portfolio, i...

1 year ago - PRNewsWire

Polar Capital Holdings Plc Enters Stake in Aeglea BioTherapeutics Inc

On July 19, 2023, Polar Capital Holdings Plc (Trades, Portfolio), a London-based investment firm, made a significant move in the biotechnology sector by investing in 3,936,198 shares in Aeglea BioTher...

1 year ago - GuruFocus

Aeglea BioTherapeutics Announces Sale of Pegzilarginase to Immedica Pharma

Global rights to pegzilarginase in development for Arginase 1 Deficiency sold to Immedica Pharma for $15 million upfront cash proceeds and up to $100 million of contingent milestone payments Marketing...

1 year ago - PRNewsWire