SPDR S&P BIOTECH ETF (XBI)

XBI Holdings List

As of Feb 20, 2025

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No.	Symbol	Name	% Weight	Shares
1	GILD	Gilead Sciences, Inc.	2.79%	1,551,992
2	ABBV	AbbVie Inc.	2.70%	822,195
3	INSM	Insmed Incorporated	2.64%	1,932,179
4	AMGN	Amgen Inc.	2.55%	524,337
5	BMRN	BioMarin Pharmaceutical Inc.	2.44%	2,173,307
6	VRTX	Vertex Pharmaceuticals Incorporated	2.40%	306,182
7	UTHR	United Therapeutics Corporation	2.37%	395,942
8	NTRA	Natera, Inc.	2.35%	857,873
9	ALNY	Alnylam Pharmaceuticals, Inc.	2.31%	564,068
10	INCY	Incyte Corporation	2.30%	1,977,780
11	HALO	Halozyme Therapeutics, Inc.	2.17%	2,312,204
12	PCVX	Vaxcyte, Inc.	2.12%	1,574,704
13	NBIX	Neurocrine Biosciences, Inc.	2.12%	1,118,146
14	REGN	Regeneron Pharmaceuticals, Inc.	2.11%	185,508
15	BIIB	Biogen Inc.	2.04%	910,539
16	MDGL	Madrigal Pharmaceuticals, Inc.	2.03%	353,921
17	SRPT	Sarepta Therapeutics, Inc.	2.02%	1,143,505
18	MRNA	Moderna, Inc.	1.84%	3,345,528
19	EXAS	Exact Sciences Corporation	1.83%	2,270,146
20	TGTX	TG Therapeutics, Inc.	1.79%	3,539,922
21	BBIO	BridgeBio Pharma, Inc.	1.61%	2,673,371
22	VKTX	Viking Therapeutics, Inc.	1.50%	2,896,716
23	CYTK	Cytokinetics, Incorporated	1.47%	1,765,248
24	BPMC	Blueprint Medicines Corporation	1.46%	949,538
25	CRSP	CRISPR Therapeutics AG	1.46%	1,771,716
26	ADMA	ADMA Biologics, Inc.	1.44%	5,481,779
27	IONS	Ionis Pharmaceuticals, Inc.	1.35%	2,535,547
28	ROIV	Roivant Sciences Ltd.	1.33%	7,613,405
29	ALKS	Alkermes plc	1.30%	2,239,401
30	EXEL	Exelixis, Inc.	1.30%	2,263,232
31	SWTX	SpringWorks Therapeutics, Inc.	1.29%	1,314,093
32	RVMD	Revolution Medicines, Inc.	1.27%	1,845,983
33	SMMT	Summit Therapeutics Inc.	1.25%	3,330,551
34	APLS	Apellis Pharmaceuticals, Inc.	1.19%	2,579,931
35	RXRX	Recursion Pharmaceuticals, Inc.	1.08%	6,364,853
36	RNA	Avidity Biosciences, Inc.	1.00%	1,891,183
37	BHVN	Biohaven Ltd.	0.94%	1,445,490
38	KRYS	Krystal Biotech, Inc.	0.87%	290,817
39	NUVL	Nuvalent, Inc.	0.85%	633,457
40	ACLX	Arcellx, Inc.	0.81%	759,300
41	RARE	Ultragenyx Pharmaceutical Inc.	0.79%	1,082,811
42	TWST	Twist Bioscience Corporation	0.73%	997,381
43	TVTX	Travere Therapeutics, Inc.	0.73%	1,886,412
44	PTCT	PTC Therapeutics, Inc.	0.69%	834,298
45	VCYT	Veracyte, Inc.	0.65%	965,948
46	PTGX	Protagonist Therapeutics, Inc.	0.64%	1,020,763
47	AKRO	Akero Therapeutics, Inc.	0.64%	776,150
48	BEAM	Beam Therapeutics Inc.	0.64%	1,183,505
49	CLDX	Celldex Therapeutics, Inc.	0.60%	1,630,095
50	DVAX	Dynavax Technologies Corporation	0.58%	2,654,360

As of Feb 20, 2025

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