XBI Holdings List

As of May 23, 2025

No.	Symbol	Name	% Weight	Shares
1	EXAS	Exact Sciences Corporation	3.26%	2,659,530
2	ALNY	Alnylam Pharmaceuticals, Inc.	3.18%	508,463
3	NBIX	Neurocrine Biosciences, Inc.	2.93%	1,130,186
4	NTRA	Natera, Inc.	2.82%	853,023
5	UTHR	United Therapeutics Corporation	2.66%	401,467
6	INCY	Incyte Corporation	2.52%	1,819,950
7	GILD	Gilead Sciences, Inc.	2.50%	1,081,376
8	BPMC	Blueprint Medicines Corporation	2.48%	1,132,717
9	INSM	Insmed Incorporated	2.42%	1,664,870
10	EXEL	Exelixis, Inc.	2.40%	2,625,148
11	BIIB	Biogen Inc.	2.38%	879,314
12	VRTX	Vertex Pharmaceuticals Incorporated	2.34%	248,812
13	AMGN	Amgen Inc.	2.31%	394,507
14	ABBV	AbbVie Inc.	2.29%	581,225
15	REGN	Regeneron Pharmaceuticals, Inc.	2.27%	178,808
16	MRNA	Moderna, Inc.	1.99%	3,520,985
17	MDGL	Madrigal Pharmaceuticals, Inc.	1.97%	341,116
18	BMRN	BioMarin Pharmaceutical Inc.	1.85%	1,493,372
19	BBIO	BridgeBio Pharma, Inc.	1.66%	2,305,156
20	RVMD	Revolution Medicines, Inc.	1.60%	1,863,664
21	TGTX	TG Therapeutics, Inc.	1.54%	2,074,122
22	HALO	Halozyme Therapeutics, Inc.	1.49%	1,267,212
23	SMMT	Summit Therapeutics Inc.	1.46%	2,620,103
24	IONS	Ionis Pharmaceuticals, Inc.	1.43%	2,010,022
25	ROIV	Roivant Sciences Ltd.	1.32%	5,653,845
26	CRSP	CRISPR Therapeutics AG	1.32%	1,665,422
27	SWTX	SpringWorks Therapeutics, Inc.	1.27%	1,265,128
28	VKTX	Viking Therapeutics, Inc.	1.22%	2,095,993
29	ADMA	ADMA Biologics, Inc.	1.12%	2,547,079
30	CYTK	Cytokinetics, Incorporated	1.11%	1,682,063
31	RNA	Avidity Biosciences, Inc.	1.09%	1,651,663
32	ALKS	Alkermes plc	1.08%	1,715,784
33	ACAD	ACADIA Pharmaceuticals Inc.	1.08%	2,284,269
34	PCVX	Vaxcyte, Inc.	1.05%	1,503,259
35	NUVL	Nuvalent, Inc.	0.92%	583,832
36	ACLX	Arcellx, Inc.	0.92%	667,310
37	SRPT	Sarepta Therapeutics, Inc.	0.91%	1,111,545
38	RYTM	Rhythm Pharmaceuticals, Inc.	0.88%	658,383
39	SLNO	Soleno Therapeutics, Inc.	0.88%	528,736
40	AKRO	Akero Therapeutics, Inc.	0.84%	844,870
41	SRRK	Scholar Rock Holding Corporation	0.82%	1,273,544
42	RARE	Ultragenyx Pharmaceutical Inc.	0.78%	1,012,811
43	APLS	Apellis Pharmaceuticals, Inc.	0.77%	2,054,375
44	CRNX	Crinetics Pharmaceuticals, Inc.	0.75%	1,164,740
45	KRYS	Krystal Biotech, Inc.	0.74%	275,692
46	VCYT	Veracyte, Inc.	0.74%	1,265,549
47	ARWR	Arrowhead Pharmaceuticals, Inc.	0.72%	2,198,782
48	TWST	Twist Bioscience Corporation	0.69%	1,132,216
49	AGIO	Agios Pharmaceuticals, Inc.	0.69%	1,067,849
50	BCRX	BioCryst Pharmaceuticals, Inc.	0.66%	2,889,147
51	PTCT	PTC Therapeutics, Inc.	0.64%	650,934
52	CPRX	Catalyst Pharmaceuticals, Inc.	0.63%	1,194,102
53	GRAL	GRAIL, Inc.	0.60%	694,465
54	RXRX	Recursion Pharmaceuticals, Inc.	0.60%	6,824,793
55	TVTX	Travere Therapeutics, Inc.	0.56%	1,653,935
56	IDYA	IDEAYA Biosciences, Inc.	0.56%	1,384,398
57	MIRM	Mirum Pharmaceuticals, Inc.	0.56%	591,444
58	ARQT	Arcutis Biotherapeutics, Inc.	0.55%	1,828,904
59	CLDX	Celldex Therapeutics, Inc.	0.54%	1,235,564
60	PTGX	Protagonist Therapeutics, Inc.	0.50%	504,768
61	BEAM	Beam Therapeutics Inc.	0.50%	1,367,100
62	NVAX	Novavax, Inc.	0.49%	3,167,317
63	IMVT	Immunovant, Inc.	0.49%	1,583,449
64	VCEL	Vericel Corporation	0.48%	543,938
65	BHVN	Biohaven Ltd.	0.46%	1,364,950
66	CGON	CG Oncology, Inc.	0.45%	814,630
67	KYMR	Kymera Therapeutics, Inc.	0.43%	672,627
68	DNLI	Denali Therapeutics Inc.	0.43%	1,472,763
69	DYN	Dyne Therapeutics, Inc.	0.42%	1,680,610
70	APGE	Apogee Therapeutics, Inc.	0.42%	490,393
71	SNDX	Syndax Pharmaceuticals, Inc.	0.42%	1,956,401
72	CDNA	CareDx, Inc	0.41%	1,132,771
73	VERA	Vera Therapeutics, Inc.	0.41%	967,954
74	NTLA	Intellia Therapeutics, Inc.	0.41%	2,053,892
75	IRON	Disc Medicine, Inc.	0.40%	388,198
76	DVAX	Dynavax Technologies Corporation	0.40%	1,874,625
77	FOLD	Amicus Therapeutics, Inc.	0.39%	2,894,049
78	ARDX	Ardelyx, Inc.	0.38%	4,486,923
79	VRDN	Viridian Therapeutics, Inc.	0.35%	1,207,406
80	JANX	Janux Therapeutics, Inc.	0.35%	641,769
81	ETNB	89bio, Inc.	0.32%	1,565,337
82	GERN	Geron Corporation	0.31%	10,054,493
83	QURE	uniQure N.V.	0.31%	941,856
84	SPRY	ARS Pharmaceuticals, Inc.	0.28%	859,088
85	PRAX	Praxis Precision Medicines, Inc.	0.27%	333,528
86	MNKD	MannKind Corporation	0.27%	3,010,453
87	NRIX	Nurix Therapeutics, Inc.	0.26%	1,255,546
88	SYRE	Spyre Therapeutics, Inc.	0.26%	802,036
89	RCUS	Arcus Biosciences, Inc.	0.25%	1,281,146
90	RCKT	Rocket Pharmaceuticals, Inc.	0.24%	1,777,705
91	AVXL	Anavex Life Sciences Corp.	0.24%	1,453,459
92	IMNM	Immunome, Inc.	0.21%	1,168,781
93	CAPR	Capricor Therapeutics, Inc.	0.21%	946,446
94	IBRX	ImmunityBio, Inc.	0.20%	3,701,365
95	ALT	Altimmune, Inc.	0.20%	1,638,517
96	COGT	Cogent Biosciences, Inc.	0.20%	1,912,379
97	KROS	Keros Therapeutics, Inc.	0.20%	631,049
98	VIR	Vir Biotechnology, Inc.	0.19%	1,951,728
99	IOVA	Iovance Biotherapeutics, Inc.	0.18%	4,807,460
100	DAWN	Day One Biopharmaceuticals, Inc.	0.18%	1,359,013
101	KURA	Kura Oncology, Inc.	0.18%	1,495,252
102	EBS	Emergent BioSolutions Inc.	0.17%	1,267,088
103	XNCR	Xencor, Inc.	0.16%	989,172
104	REPL	Replimune Group, Inc.	0.16%	896,513
105	ANAB	AnaptysBio, Inc.	0.16%	355,529
106	ARCT	Arcturus Therapeutics Holdings Inc.	0.15%	564,224
107	RLAY	Relay Therapeutics, Inc.	0.15%	2,338,749
108	AKBA	Akebia Therapeutics, Inc.	0.15%	2,356,544
109	STOK	Stoke Therapeutics, Inc.	0.14%	703,748
110	MYGN	Myriad Genetics, Inc.	0.14%	1,674,183
111	ORIC	ORIC Pharmaceuticals, Inc.	0.12%	883,096
112	VERV	Verve Therapeutics, Inc.	0.12%	1,284,085
113	HUMA	Humacyte, Inc.	0.11%	2,109,869
114	DNTH	Dianthus Therapeutics, Inc.	0.11%	272,236
115	MDXG	MiMedx Group, Inc.	0.11%	747,687
116	CGEM	Cullinan Therapeutics, Inc.	0.11%	626,660
117	RIGL	Rigel Pharmaceuticals, Inc.	0.10%	244,000
118	SANA	Sana Biotechnology, Inc.	0.10%	2,225,445
119	-	SSI US GOV MONEY MARKET CLASS	0.09%	4,234,119
120	AVBP	ArriVent BioPharma, Inc.	0.09%	198,416
121	KALV	KalVista Pharmaceuticals, Inc.	0.07%	299,514
122	PRTA	Prothena Corporation plc	0.07%	501,537
123	ABUS	Arbutus Biopharma Corporation	0.07%	945,058
124	-	CONTRA INHIBRX INC	0.02%	1,645,973
125	ORGO	Organogenesis Holdings Inc.	0.02%	364,800
126	-	CONTRA MIRATI THERAPEU	0.02%	1,369,552
127	2200963D	OMNIAB INC 12.5 EARNOUT	0.00%	161,959
128	2200964D	OMNIAB INC 15.00 EARNOUT	0.00%	161,959
129	-	US DOLLAR	-0.00%	-336

As of May 23, 2025

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