State Street SPDR S&P Biotech ETF (XBI)
NYSEARCA: XBI · Real-Time Price · USD
121.67
-1.72 (-1.39%)
At close: Dec 30, 2025, 4:00 PM EST
121.42
-0.25 (-0.21%)
Pre-market: Dec 31, 2025, 5:01 AM EST
XBI Holdings Information
XBI is an equity ETF with a total of 156 individual holdings. The top holdings are Amicus Therapeutics stock at 1.47%, Praxis Precision Medicines at 1.42%, Travere Therapeutics at 1.38%, BioMarin Pharmaceutical at 1.36%, and Exelixis at 1.35%.
Total Holdings
156
Top 10 Percentage
13.56%
Asset Class
Equity
ETF Category
Health
Assets
8.49B
PE Ratio
n/a
Sector Allocation
Top 25 Holdings
| No. | Symbol | Name | % Weight |
|---|---|---|---|
| 1 | FOLD | Amicus Therapeutics, Inc. | 1.47% |
| 2 | PRAX | Praxis Precision Medicines, Inc. | 1.42% |
| 3 | TVTX | Travere Therapeutics, Inc. | 1.38% |
| 4 | BMRN | BioMarin Pharmaceutical Inc. | 1.36% |
| 5 | EXEL | Exelixis, Inc. | 1.35% |
| 6 | HALO | Halozyme Therapeutics, Inc. | 1.34% |
| 7 | REGN | Regeneron Pharmaceuticals, Inc. | 1.31% |
| 8 | RYTM | Rhythm Pharmaceuticals, Inc. | 1.31% |
| 9 | MRNA | Moderna, Inc. | 1.31% |
| 10 | ROIV | Roivant Sciences Ltd. | 1.31% |
| 11 | PCVX | Vaxcyte, Inc. | 1.31% |
| 12 | MDGL | Madrigal Pharmaceuticals, Inc. | 1.30% |
| 13 | KRYS | Krystal Biotech, Inc. | 1.29% |
| 14 | PTCT | PTC Therapeutics, Inc. | 1.28% |
| 15 | AMGN | Amgen Inc. | 1.27% |
| 16 | INCY | Incyte Corporation | 1.27% |
| 17 | BBIO | BridgeBio Pharma, Inc. | 1.27% |
| 18 | UTHR | United Therapeutics Corporation | 1.27% |
| 19 | VRTX | Vertex Pharmaceuticals Incorporated | 1.26% |
| 20 | RVMD | Revolution Medicines, Inc. | 1.26% |
| 21 | GILD | Gilead Sciences, Inc. | 1.26% |
| 22 | ABBV | AbbVie Inc. | 1.25% |
| 23 | CYTK | Cytokinetics, Incorporated | 1.25% |
| 24 | IONS | Ionis Pharmaceuticals, Inc. | 1.24% |
| 25 | RNA | Avidity Biosciences, Inc. | 1.23% |
As of Dec 29, 2025