State Street SPDR S&P Biotech ETF (XBI)
NYSEARCA: XBI · Real-Time Price · USD
152.72
-0.52 (-0.34%)
Oct 21, 2026, 3:11 PM EDT - Market open

XBI Holdings Information

XBI is an equity ETF with a total of 167 individual holdings. The top holdings are Moderna stock at 2.64%, Natera at 1.82%, Halozyme Therapeutics at 1.71%, Biogen at 1.71%, and AbbVie at 1.70%.

Total Holdings
167
Top 10 Percentage
17.84%
Asset Class
Equity
ETF Category
Health
Assets
9.64B
PE Ratio
22.31

Breakdown by Sector

Top 25 Holdings

Oct 20, 2026
No.SymbolNameWeight% Weight SharesStock Price% Change
1MRNAModerna, Inc.2.64%1,165,310252.244.20%
2NTRANatera, Inc.1.82%478,371417.972.97%
3HALOHalozyme Therapeutics, Inc.1.71%1,471,386124.600.18%
4BIIBBiogen Inc.1.71%749,894241.71-0.57%
5ABBVAbbVie Inc.1.70%629,866283.56-1.91%
6TWSTTwist Bioscience Corporation1.68%1,258,912151.636.26%
7IOVAIovance Biotherapeutics, Inc.1.67%12,031,43114.72-0.94%
8AMGNAmgen Inc.1.66%403,920437.88-0.24%
9EXELExelixis, Inc.1.63%2,709,06064.580.30%
10UTHRUnited Therapeutics Corporation1.62%311,846563.991.83%
11GILDGilead Sciences, Inc.1.59%1,084,979153.75-1.76%
12SYRESpyre Therapeutics, Inc.1.55%1,817,67792.911.65%
13REGNRegeneron Pharmaceuticals, Inc.1.48%195,634805.74-0.22%
14TGTXTG Therapeutics, Inc.1.48%2,891,46853.03-2.76%
15VRTXVertex Pharmaceuticals Incorporated1.46%303,295524.151.84%
16ALKSAlkermes plc1.44%3,480,57143.79-0.73%
17RVMDRevolution Medicines, Inc.1.40%760,985194.13-1.23%
18PTGXProtagonist Therapeutics, Inc.1.40%1,083,780138.420.31%
19KRYSKrystal Biotech, Inc.1.38%454,024321.14-1.32%
20PTCTPTC Therapeutics, Inc.1.38%2,338,63162.51-0.65%
21INCYIncyte Corporation1.37%1,253,932113.52-2.65%
22CRSPCRISPR Therapeutics AG1.36%2,904,83650.130.50%
23NBIXNeurocrine Biosciences, Inc.1.35%1,018,550141.34-0.46%
24ALNYAlnylam Pharmaceuticals, Inc.1.32%612,450226.00-2.04%
25PCVXVaxcyte, Inc.1.32%2,128,46863.58-4.01%
Showing 25 of 167 holdings
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