Silence Therapeutics plc (FRA:XRP2)

Germany flag Germany · Delayed Price · Currency is EUR
8.50
0.00 (0.00%)
At close: Jun 26, 2026
Market Cap419.95M +94.9%
Revenue (ttm)727.67K -97.0%
Net Income-65.08M
EPS-1.38
Shares Out n/a
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume200
Open8.50
Previous Close8.50
Day's Range8.50 - 8.50
52-Week Range3.40 - 8.50
Betan/a
Analystsn/a
Price Targetn/a
Earnings DateAug 5, 2026

About Silence Therapeutics

Silence Therapeutics plc, a biotechnology company, engages in the discovery and development of novel molecules incorporating short interfering ribonucleic acid (siRNA) to inhibit the expression of specific target genes in hematology, cardiovascular, and rare diseases. The company develops Divesiran (SLN124), which is in Phase 2 development for polycythemia vera, and SLN548 for complement-mediated renal diseases. It also develops Zerlasiran (SLN360) for cardiovascular disease associated with elevated lipoprotein(a); SLN312 for dyslipidemia; SLN3... [Read more]

Industry Biological Products, Except Diagnostic Substances
Founded 1994
Employees 88
Stock Exchange Frankfurt Stock Exchange
Ticker Symbol XRP2

Financial Performance

In 2025, Silence Therapeutics's revenue was $559,000, a decrease of -98.71% compared to the previous year's $43.26 million. Losses were -$88.61 million, 95.6% more than in 2024.

Financial numbers in USD Financial Statements

News

Cantor starts ‘materially undervalued’ Silence Therapeutics at Overweight

Cantor Fitzgerald analyst Prakhar Agrawal initiated coverage of Silence Therapeutics (SLN) with an Overweight rating and no price target Silence is a clinical-stage biotech focused on developing siRNA...

3 days ago - TheFly

Silence Therapeutics initiated with an Overweight at Cantor Fitzgerald

Cantor Fitzgerald analyst Prakhar Agrawal initiated coverage of Silence Therapeutics (SLN) with an Overweight rating.

3 days ago - TheFly

Silence Therapeutics Slides: Corporate presentation

Silence Therapeutics has posted slides in relation to its latest quarterly earnings report, which was published on June 23, 2026.

4 days ago - Filings

Silence Therapeutics highlights follow-up data on divesiran at EHA 2026

Silence Therapeutics (SLN) presented follow-up and quality-of-life data from the Phase 1 SANRECO study evaluating divesiran, a first-in-class siRNA therapy targeting TMPRSS6, in 21 phlebotomy-dependen...

16 days ago - TheFly

Silence Therapeutics Highlights Follow-Up Data at EHA 2026 Demonstrating Durable Efficacy and Potential Best-in-Class Profile for Divesiran in Polycythemia Vera

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (Nasdaq: SLN), a global clinical-stage biotechnology company developing novel siRNA (short interfering RNA) therapies, today ...

16 days ago - Business Wire

Silence Therapeutics Transcript: Jefferies Global Healthcare Conference 2026

The session highlighted progress on a siRNA-based pipeline, with the lead PV program nearing phase II data readout in August. The company targets durable, less frequent dosing and a strong safety profile, with phase III and commercialization preparations underway.

23 days ago - Transcripts

Silence Therapeutics to Participate in Jefferies Global Healthcare Conference

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (Nasdaq: SLN), a global clinical-stage biotechnology company developing novel siRNA (short interfering RNA) therapies, today ...

4 weeks ago - Business Wire

Silence Therapeutics Transcript: H.C. Wainwright 4th Annual BioConnect Investor Conference

The company is advancing a robust siRNA pipeline targeting cardiometabolic and hematological diseases, with key milestones expected for divesiran (polycythemia vera) and zerlasiran (Lp(a)) in 2026. Strong clinical execution, differentiated technology, and a growing early-stage pipeline position it for significant data-driven progress over the next year.

5 weeks ago - Transcripts

Silence Therapeutics files $300M ordinary shares offering

16:11 EDT Silence Therapeutics (SLN) files $300M ordinary shares offering

5 weeks ago - TheFly

Silence Therapeutics Registration statement: Registration filing

Silence Therapeutics filed a registration statement on May 18, 2026, providing details about a securities offering with the SEC.

5 weeks ago - Filings

Silence Therapeutics to Participate in H.C. Wainwright BioConnect Investor Conference

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (Nasdaq: SLN), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today announced that...

6 weeks ago - Business Wire

Silence Therapeutics price target lowered to $27 from $35 at Chardan

Chardan analyst Keay Nakae lowered the firm’s price target on Silence Therapeutics (SLN) to $27 from $35 and keeps a Buy rating on the shares. The firm updated the company’s…

7 weeks ago - TheFly

Silence Therapeutics reports Q1 EPS (11c) vs. (20c) last year

Reports revenue $422,000 vs. $142,000 last year, “The Silence team continues to advance research supporting the broad potential of our mRNAi GOLD platform, and we remain well positioned as we…

7 weeks ago - TheFly

Silence Therapeutics Highlights Recent Business Achievements and Reports First Quarter 2026 Financial Results

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...

7 weeks ago - Business Wire

Silence Therapeutics Earnings release: Q1 2026

Silence Therapeutics released its Q1 2026 earnings on May 7, 2026, summarizing the period's financial results.

7 weeks ago - Filings

Silence Therapeutics Quarterly report: Q1 2026

Silence Therapeutics has published its Q1 2026 quarterly earnings report on May 7, 2026.

7 weeks ago - Filings

Silence Therapeutics Slides: Corporate presentation

Silence Therapeutics has posted slides in relation to its latest quarterly earnings report, which was published on May 6, 2026.

7 weeks ago - Filings

Silence Therapeutics Proxy statement: Proxy filing

Silence Therapeutics filed a proxy statement on April 29, 2026, providing details for shareholder voting and corporate governance matters.

2 months ago - Filings

Silence Therapeutics Highlights Recent Business Achievements and Reports Fourth Quarter and Full Year 2025 Financial Results

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN, a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today reported financ...

4 months ago - Business Wire

Silence Therapeutics Annual report: Q4 2025

Silence Therapeutics has published its Q4 2025 annual report on March 5, 2026.

4 months ago - Filings

Silence Therapeutics Earnings release: Q4 2025

Silence Therapeutics released its Q4 2025 earnings on March 5, 2026, summarizing the period's financial results.

4 months ago - Filings

Silence Therapeutics Annual report: Q4 2025

Silence Therapeutics has published its Q4 2025 annual report on March 5, 2026.

4 months ago - Filings

Silence Therapeutics CEO Craig Tooman to end employment

Silence Therapeutics (SLN) announced that Craig Tooman, who has served as the company’s president, CEO and board member since 2022, agreed by mutual consent to end his employment with the…

6 months ago - TheFly

Silence Therapeutics Announces Leadership Changes

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...

6 months ago - Business Wire

Silence Therapeutics Transcript: Jefferies London Healthcare Conference 2025

A proprietary siRNA platform supports three clinical programs, including phase II SLN124 for polycythemia vera and phase III-ready SLN360 for Lp(a), both showing robust efficacy and differentiated dosing. Key milestones include phase II data in Q3 2025 and strong financial runway into 2028.

7 months ago - Transcripts