Karyopharm Therapeutics Inc. (KPTI)

Karyopharm Therapeutics Income Statement

Financials in millions USD. Fiscal year is January - December.

Fiscal Year	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Dec 31, 2025	Dec 31, 2024	Dec 31, 2023	Dec 31, 2022	Dec 31, 2021
Revenue	146.07	145.24	146.03	157.07	209.82
Revenue Growth (YoY)	0.57%	-0.55%	-7.03%	-25.14%	94.12%
Cost of Revenue	5.95	6.01	4.94	5.21	3.4
Gross Profit	140.12	139.23	141.09	151.86	206.42
Selling, General & Admin	105.21	115.44	131.88	145.4	143.85
Research & Development	125.62	143.23	138.75	148.66	160.84
Total Operating Expenses	230.83	258.67	270.63	294.06	304.69
Operating Income	-90.71	-119.44	-129.54	-142.2	-98.27
Interest Income	2.77	7.4	10.94	2.36	0.58
Interest Expense	-45.85	-37.42	-23.82	-25	-26.05
Other Non-Operating Income (Expense)	-62.21	73.1	-0.36	-0.08	-0.09
Total Non-Operating Income (Expense)	-105.29	43.08	-13.24	-22.72	-25.55
Pretax Income	-196	-76.37	-142.78	-164.92	-123.82
Provision for Income Taxes	-0.04	-0.06	-0.32	-0.37	-0.27
Net Income	-196.04	-76.42	-143.1	-165.29	-124.09
Net Income to Common	-196.04	-76.42	-143.1	-165.29	-124.09
Shares Outstanding (Basic)	11	8	8	5	5
Shares Outstanding (Diluted)	11	8	8	5	5
Shares Change (YoY)	29.33%	11.02%	39.54%	8.85%	4.41%
EPS (Basic)	-17.93	-9.41	-18.79	-30.30	-24.75
EPS (Diluted)	-17.93	-14.00	-18.79	-30.30	-24.75
Free Cash Flow	-75.37	-127.63	-92.72	-149.67	-107.33
Free Cash Flow Per Share	-6.89	-15.09	-12.17	-27.42	-21.40
Gross Margin	95.93%	95.86%	96.62%	96.68%	98.38%
Operating Margin	-62.10%	-82.24%	-88.71%	-90.53%	-46.84%
Profit Margin	-134.15%	-52.54%	-97.55%	-104.76%	-58.89%
FCF Margin	-51.60%	-87.88%	-63.49%	-95.29%	-51.15%
EBITDA	-90.41	-119.1	-129.01	-141.58	-97.48
EBITDA Margin	-61.90%	-82.01%	-88.34%	-90.14%	-46.46%
EBIT	-90.71	-119.44	-129.54	-142.2	-98.27
EBIT Margin	-62.10%	-82.24%	-88.71%	-90.53%	-46.84%
Effective Tax Rate	0.02%	0.07%	0.23%	0.22%	0.22%

Updated Dec 31, 2025. Data Source: Fiscal.ai. Standard template. Financial Sources.

SEC Filings: 10-K · 10-Q