Karyopharm Therapeutics Inc. (KPTI)
NASDAQ: KPTI · Real-Time Price · USD
8.38
-0.17 (-1.99%)
At close: Mar 17, 2026, 4:00 PM EDT
8.73
+0.35 (4.20%)
After-hours: Mar 17, 2026, 7:49 PM EDT

Karyopharm Therapeutics Statistics

Total Valuation

KPTI has a market cap or net worth of $153.72 million. The enterprise value is $395.92 million.

Market Cap153.72M
Enterprise Value 395.92M

Important Dates

The last earnings date was Thursday, February 12, 2026, before market open.

Earnings Date Feb 12, 2026
Ex-Dividend Date n/a

Share Statistics

KPTI has 18.34 million shares outstanding. The number of shares has increased by 29.33% in one year.

Current Share Class 18.34M
Shares Outstanding 18.34M
Shares Change (YoY) +29.33%
Shares Change (QoQ) +106.53%
Owned by Insiders (%) 0.76%
Owned by Institutions (%) 49.26%
Float 16.27M

Valuation Ratios

PE Ratio n/a
Forward PE n/a
PS Ratio 1.05
Forward PS 1.08
PB Ratio n/a
P/TBV Ratio n/a
P/FCF Ratio n/a
P/OCF Ratio n/a
PEG Ratio n/a
Financial Ratio History

Enterprise Valuation

EV / Earnings n/a
EV / Sales 2.71
EV / EBITDA n/a
EV / EBIT n/a
EV / FCF n/a

Financial Position

The company has a current ratio of 1.12

Current Ratio 1.12
Quick Ratio 0.98
Debt / Equity n/a
Debt / EBITDA n/a
Debt / FCF n/a
Interest Coverage -1.98

Financial Efficiency

Return on Equity (ROE) n/a
Return on Assets (ROA) -41.56%
Return on Invested Capital (ROIC) -119.32%
Return on Capital Employed (ROCE) -554.58%
Weighted Average Cost of Capital (WACC) 9.68%
Revenue Per Employee $640,645
Profits Per Employee -$859,820
Employee Count228
Asset Turnover 1.07
Inventory Turnover 29.98

Taxes

In the past 12 months, KPTI has paid $43,000 in taxes.

Income Tax 43,000
Effective Tax Rate n/a

Stock Price Statistics

The stock price has increased by +24.15% in the last 52 weeks. The beta is 0.20, so KPTI's price volatility has been lower than the market average.

Beta (5Y) 0.20
52-Week Price Change +24.15%
50-Day Moving Average 7.90
200-Day Moving Average 6.15
Relative Strength Index (RSI) 49.32
Average Volume (20 Days) 647,314

Short Selling Information

The latest short interest is 2.97 million, so 16.20% of the outstanding shares have been sold short.

Short Interest 2.97M
Short Previous Month 2.47M
Short % of Shares Out 16.20%
Short % of Float 18.27%
Short Ratio (days to cover) 4.51

Income Statement

In the last 12 months, KPTI had revenue of $146.07 million and -$196.04 million in losses. Loss per share was -$17.93.

Revenue146.07M
Gross Profit 14.50M
Operating Income -90.71M
Pretax Income -196.00M
Net Income -196.04M
EBITDA -90.41M
EBIT -90.71M
Loss Per Share -$17.93
Full Income Statement

Balance Sheet

The company has $63.74 million in cash and $305.95 million in debt, with a net cash position of -$242.20 million or -$13.20 per share.

Cash & Cash Equivalents 63.74M
Total Debt 305.95M
Net Cash -242.20M
Net Cash Per Share -$13.20
Equity (Book Value) -292.93M
Book Value Per Share -16.00
Working Capital 11.09M
Full Balance Sheet

Cash Flow

Operating Cash Flow -75.37M
Capital Expenditures n/a
Free Cash Flow -75.37M
FCF Per Share -$4.11
Full Cash Flow Statement

Margins

Gross margin is 9.93%, with operating and profit margins of -62.10% and -134.21%.

Gross Margin 9.93%
Operating Margin -62.10%
Pretax Margin -134.18%
Profit Margin -134.21%
EBITDA Margin -61.90%
EBIT Margin -62.10%
FCF Margin n/a

Dividends & Yields

KPTI does not appear to pay any dividends at this time.

Dividend Per Share n/a
Dividend Yield n/a
Dividend Growth (YoY) n/a
Years of Dividend Growth n/a
Payout Ratio n/a
Buyback Yield -29.33%
Shareholder Yield -29.33%
Earnings Yield -127.53%
FCF Yield -49.03%

Analyst Forecast

The average price target for KPTI is $17.50, which is 108.83% higher than the current price. The consensus rating is "Strong Buy".

Price Target $17.50
Price Target Difference 108.83%
Analyst Consensus Strong Buy
Analyst Count 7
Revenue Growth Forecast (5Y) 36.75%
EPS Growth Forecast (5Y) n/a
Stock Forecasts

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value n/a
Lynch Upside n/a
Graham Number n/a
Graham Upside n/a

Stock Splits

The last stock split was on February 26, 2025. It was a reverse split with a ratio of 1:15.

Last Split Date Feb 26, 2025
Split Type Reverse
Split Ratio 1:15

Scores

KPTI has an Altman Z-Score of -23.92 and a Piotroski F-Score of 3. A Z-score under 3 suggests an increased risk of bankruptcy.

Altman Z-Score -23.92
Piotroski F-Score 3