Karyopharm Therapeutics Statistics
Total Valuation
KPTI has a market cap or net worth of $95.83 million. The enterprise value is $319.87 million.
Important Dates
The last earnings date was Monday, November 3, 2025, before market open.
| Earnings Date | Nov 3, 2025 |
| Ex-Dividend Date | n/a |
Share Statistics
KPTI has 17.05 million shares outstanding. The number of shares has increased by 7.52% in one year.
| Current Share Class | 17.05M |
| Shares Outstanding | 17.05M |
| Shares Change (YoY) | +7.52% |
| Shares Change (QoQ) | +0.57% |
| Owned by Insiders (%) | 0.59% |
| Owned by Institutions (%) | 32.44% |
| Float | 16.00M |
Valuation Ratios
| PE Ratio | n/a |
| Forward PE | n/a |
| PS Ratio | 0.33 |
| Forward PS | 0.64 |
| PB Ratio | n/a |
| P/TBV Ratio | n/a |
| P/FCF Ratio | n/a |
| P/OCF Ratio | n/a |
| PEG Ratio | n/a |
Financial Ratio HistoryEnterprise Valuation
| EV / Earnings | n/a |
| EV / Sales | 2.24 |
| EV / EBITDA | n/a |
| EV / EBIT | n/a |
| EV / FCF | n/a |
Financial Position
The company has a current ratio of 1.03
| Current Ratio | 1.03 |
| Quick Ratio | 0.89 |
| Debt / Equity | n/a |
| Debt / EBITDA | n/a |
| Debt / FCF | n/a |
| Interest Coverage | -2.34 |
Financial Efficiency
| Return on Equity (ROE) | n/a |
| Return on Assets (ROA) | -45.56% |
| Return on Invested Capital (ROIC) | -119.68% |
| Return on Capital Employed (ROCE) | -1,147.59% |
| Revenue Per Employee | $510,860 |
| Profits Per Employee | -$446,670 |
| Employee Count | 279 |
| Asset Turnover | 1.00 |
| Inventory Turnover | n/a |
Taxes
In the past 12 months, KPTI has paid $1,000 in taxes.
| Income Tax | 1,000 |
| Effective Tax Rate | n/a |
Stock Price Statistics
The stock price has decreased by -56.05% in the last 52 weeks. The beta is 0.23, so KPTI's price volatility has been lower than the market average.
| Beta (5Y) | 0.23 |
| 52-Week Price Change | -56.05% |
| 50-Day Moving Average | 5.96 |
| 200-Day Moving Average | 5.61 |
| Relative Strength Index (RSI) | 47.03 |
| Average Volume (20 Days) | 109,798 |
Short Selling Information
The latest short interest is 716,400, so 4.20% of the outstanding shares have been sold short.
| Short Interest | 716,400 |
| Short Previous Month | 648,449 |
| Short % of Shares Out | 4.20% |
| Short % of Float | 4.48% |
| Short Ratio (days to cover) | 5.62 |
Income Statement
In the last 12 months, KPTI had revenue of $142.53 million and -$124.62 million in losses. Loss per share was -$14.60.
| Revenue | 142.53M |
| Gross Profit | 148.71M |
| Operating Income | -104.14M |
| Pretax Income | -124.62M |
| Net Income | -124.62M |
| EBITDA | -103.79M |
| EBIT | -104.14M |
| Loss Per Share | -$14.60 |
Full Income StatementBalance Sheet
The company has $45.88 million in cash and $269.92 million in debt, giving a net cash position of -$224.05 million or -$13.14 per share.
| Cash & Cash Equivalents | 45.88M |
| Total Debt | 269.92M |
| Net Cash | -224.05M |
| Net Cash Per Share | -$13.14 |
| Equity (Book Value) | -269.26M |
| Book Value Per Share | -30.94 |
| Working Capital | 2.59M |
Full Balance SheetCash Flow
In the last 12 months, operating cash flow was -$89.35 million and capital expenditures $53,000, giving a free cash flow of -$89.30 million.
| Operating Cash Flow | -89.35M |
| Capital Expenditures | 53,000 |
| Free Cash Flow | -89.30M |
| FCF Per Share | -$5.24 |
Full Cash Flow StatementMargins
Gross margin is 104.34%, with operating and profit margins of -73.07% and -87.43%.
| Gross Margin | 104.34% |
| Operating Margin | -73.07% |
| Pretax Margin | -87.43% |
| Profit Margin | -87.43% |
| EBITDA Margin | -72.82% |
| EBIT Margin | -73.07% |
| FCF Margin | n/a |
Dividends & Yields
KPTI does not appear to pay any dividends at this time.
| Dividend Per Share | n/a |
| Dividend Yield | n/a |
| Dividend Growth (YoY) | n/a |
| Years of Dividend Growth | n/a |
| Payout Ratio | n/a |
| Buyback Yield | -7.52% |
| Shareholder Yield | -7.52% |
| Earnings Yield | -130.05% |
| FCF Yield | -93.19% |
Analyst Forecast
The average price target for KPTI is $22.17, which is 294.48% higher than the current price. The consensus rating is "Strong Buy".
| Price Target | $22.17 |
| Price Target Difference | 294.48% |
| Analyst Consensus | Strong Buy |
| Analyst Count | 6 |
| Revenue Growth Forecast (5Y) | 22.31% |
| EPS Growth Forecast (5Y) | n/a |
Stock ForecastsFair Value
There are several formulas that can be used to estimate the intrinsic value of a stock.
| Lynch Fair Value | n/a |
| Lynch Upside | n/a |
| Graham Number | n/a |
| Graham Upside | n/a |
Stock Splits
The last stock split was on February 26, 2025. It was a reverse split with a ratio of 1:15.
| Last Split Date | Feb 26, 2025 |
| Split Type | Reverse |
| Split Ratio | 1:15 |
Scores
KPTI has an Altman Z-Score of -26.06 and a Piotroski F-Score of 4. A Z-score under 3 suggests an increased risk of bankruptcy.
| Altman Z-Score | -26.06 |
| Piotroski F-Score | 4 |
