Upstream Bio, Inc. (UPB)
NASDAQ: UPB · Real-Time Price · USD
2.780
-0.080 (-2.80%)
Nov 13, 2026, 4:00 PM EST - Market closed
Upstream Bio Stock Forecast
UPB's stock price has decreased by -88.28% in the past year and price targets may not have had time to catch up.
Stock Price Forecast
According to 7 analysts polled by S&P Global, Upstream Bio stock has a consensus rating of "Buy" and an average price target of $21.4. The average 1-year stock price forecast is 669.78% higher than the current stock price, while the lowest is $9.00 (+223.74%) and the highest is $40 (+1,338.85%).
Price Target: $21.4 (+669.78%)
Analyst Consensus: Buy
Price Target
ChartAnalyst Ratings
The average analyst rating for Upstream Bio stock is "Buy". This means that analysts believe this stock is likely to outperform the market over the next twelve months.
Recommendation Trends
| Rating | Apr '26 | May '26 | Jun '26 | Aug '26 | Sep '26 | Nov '26 |
|---|---|---|---|---|---|---|
| Strong Buy | 5 | 5 | 6 | 6 | 5 | 4 |
| Buy | 2 | 2 | 1 | 1 | 1 | 1 |
| Hold | 1 | 1 | 2 | 2 | 2 | 2 |
| Sell | 0 | 0 | 0 | 0 | 0 | 0 |
| Strong Sell | 0 | 0 | 0 | 0 | 0 | 0 |
| Total | 8 | 8 | 9 | 9 | 8 | 7 |
Latest Forecasts
| Analyst | Firm | Rating | Rating | Action | Price Target | Upside | Date |
|---|---|---|---|---|---|---|---|
| H.C. Wainwright | H.C. Wainwright | Buy Reiterates $36 → $18 | Buy | Reiterates | $36 → $18 | +547.48% | Nov 11, 2026 |
| William Blair | William Blair | Buy Maintains n/a | Buy | Maintains | n/a | n/a | Sep 8, 2026 |
| LifeSci Capital | LifeSci Capital | Buy Maintains $19 | Buy | Maintains | $19 | +583.45% | Sep 2, 2026 |
| J.P. Morgan | J.P. Morgan | Hold Maintains $8 → $9 | Hold | Maintains | $8 → $9 | +223.74% | Aug 14, 2026 |
| Truist Financial | Truist Financial | Buy Maintains $43 → $25 | Buy | Maintains | $43 → $25 | +799.28% | Aug 11, 2026 |
Financial Forecast
Revenue This Year
2.47M
from 2.85M
Decreased by -13.52%
Revenue Next Year
975.33K
from 2.47M
Decreased by -60.48%
EPS This Year
-2.97
from -2.66
EPS Next Year
-2.63
from -2.97
EPS and Forward PE are based on non-GAAP adjusted numbers.