Upstream Bio, Inc. (UPB)
NASDAQ: UPB · Real-Time Price · USD
6.50
+0.09 (1.40%)
Jul 30, 2026, 1:35 PM EDT - Market open
Upstream Bio Stock Forecast
UPB's stock price has decreased by -55.3% in the past year and price targets may not have had time to catch up.
Stock Price Forecast
According to 9 analysts polled by S&P Global, Upstream Bio stock has a consensus rating of "Buy" and an average price target of $38.25. The average 1-year stock price forecast is 488.46% higher than the current stock price, while the lowest is $8.00 (+23.08%) and the highest is $75 (+1,053.85%).
Price Target: $38.25 (+488.46%)
Analyst Consensus: Buy
Price Target
Chart* Price targets were last updated on Jun 25, 2026.
Analyst Ratings
The average analyst rating for Upstream Bio stock is "Buy". This means that analysts believe this stock is likely to outperform the market over the next twelve months.
Recommendation Trends
| Rating | Jan '26 | Feb '26 | Mar '26 | Apr '26 | May '26 | Jun '26 |
|---|---|---|---|---|---|---|
| Strong Buy | 6 | 6 | 5 | 5 | 5 | 6 |
| Buy | 2 | 2 | 2 | 2 | 2 | 1 |
| Hold | 0 | 0 | 1 | 1 | 1 | 2 |
| Sell | 0 | 0 | 0 | 0 | 0 | 0 |
| Strong Sell | 0 | 0 | 0 | 0 | 0 | 0 |
| Total | 8 | 8 | 8 | 8 | 8 | 9 |
Latest Forecasts
| Analyst | Firm | Rating | Rating | Action | Price Target | Upside | Date |
|---|---|---|---|---|---|---|---|
| Piper Sandler | Piper Sandler | Buy Maintains $75 | Buy | Maintains | $75 | +1,053.85% | Jun 25, 2026 |
| J.P. Morgan | J.P. Morgan | Hold Downgrades $35 → $8 | Hold | Downgrades | $35 → $8 | +23.08% | Jun 12, 2026 |
| H.C. Wainwright | H.C. Wainwright | Buy Initiates $36 | Buy | Initiates | $36 | +453.85% | Jun 3, 2026 |
| William Blair | William Blair | Buy Maintains n/a | Buy | Maintains | n/a | n/a | May 19, 2026 |
| LifeSci Capital | LifeSci Capital | Buy Maintains $42 | Buy | Maintains | $42 | +546.15% | May 19, 2026 |
Financial Forecast
Revenue This Year
2.04M
from 2.85M
Decreased by -28.58%
Revenue Next Year
1.65M
from 2.04M
Decreased by -19.01%
EPS This Year
-2.84
from -2.66
EPS Next Year
-2.89
from -2.84
EPS and Forward PE are based on non-GAAP adjusted numbers.