Upstream Bio, Inc. (UPB)
NASDAQ: UPB · Real-Time Price · USD
5.96
-0.23 (-3.72%)
At close: Sep 9, 2026, 4:00 PM EDT
5.88
-0.08 (-1.34%)
After-hours: Sep 9, 2026, 5:15 PM EDT

Upstream Bio Stock Forecast

UPB's stock price has decreased by -68.18% in the past year and price targets may not have had time to catch up.

Stock Price Forecast

According to 7 analysts polled by S&P Global, Upstream Bio stock has a consensus rating of "Buy" and an average price target of $31.14. The average 1-year stock price forecast is 422.48% higher than the current stock price, while the lowest is $9.00 (+51.01%) and the highest is $75 (+1,158.39%).

Price Target: $31.14 (+422.48%)
Analyst Consensus: Buy

Price Target

Chart
TargetLowAverageMedianHigh
Price$9.00$31.14$25$75
Change+51.01%+422.48%+319.46%+1158.4%

Analyst Ratings

The average analyst rating for Upstream Bio stock is "Buy". This means that analysts believe this stock is likely to outperform the market over the next twelve months.

Recommendation Trends

Chart
RatingMar '26Apr '26May '26Jun '26Aug '26Sep '26
Strong Buy555665
Buy222111
Hold111222
Sell000000
Strong Sell000000
Total888998

Latest Forecasts

AnalystFirmRatingRatingActionPrice TargetUpsideDate
William Blair
William Blair
Buy
Maintains
n/a
BuyMaintainsn/an/aSep 8, 2026
H.C. Wainwright
H.C. Wainwright
Buy
Reiterates
$36
BuyReiterates$36+504.03%Sep 2, 2026
LifeSci Capital
LifeSci Capital
Buy
Maintains
$19
BuyMaintains$19+218.79%Sep 2, 2026
J.P. Morgan
J.P. Morgan
Hold
Maintains
$8$9
HoldMaintains$8$9+51.01%Aug 14, 2026
Truist Financial
Truist Financial
Buy
Maintains
$43$25
BuyMaintains$43$25+319.46%Aug 11, 2026
More Analyst Ratings

Financial Forecast

Revenue This Year
2.71M
from 2.85M
Decreased by -5.21%
Revenue Next Year
1.36M
from 2.71M
Decreased by -49.64%
EPS This Year
-2.90
from -2.66
EPS Next Year
-2.77
from -2.90
Fiscal YearFY 2022FY 2023FY 2024FY 2025FY 2026
Period EndingDec 31, 2022Dec 31, 2023Dec 31, 2024Dec 31, 2025Dec 31, 2026
Revenue
1.21M2.38M2.37M2.85M2.71M
Revenue Growth
-96.37%-0.42%20.42%-5.21%
Gross Profit
1.21M2.38M2.37M2.85M2.71M
Gross Margin
100.00%100.00%100.00%100.00%100.00%
Operating Income
-23.91M-40.11M-77.76M-160.36M-177.04M
Net Income
-23.87M-20.54M-62.81M-143.44M-166.68M
EPS
----2.66-2.90
Free Cash Flow
--25.96M-40.98M-88.75M-173.30M
No. Analysts
----7
EPS and Forward PE are based on non-GAAP adjusted numbers.

Revenue Forecast

Revenue202620272028
High3.4M
Avg2.7M
Low1.8M

Revenue Growth

Revenue Growth202620272028
High
19.4%
Avg
-5.2%
Low
-36.9%

EPS Forecast

EPS202620272028
High-2.17
Avg-2.90
Low-3.26

EPS Growth

EPS Growth202620272028
High-
Avg-
Low-