Upstream Bio, Inc. (UPB)
NASDAQ: UPB · Real-Time Price · USD
9.88
-0.46 (-4.45%)
Apr 15, 2026, 4:00 PM EDT - Market closed

Upstream Bio Statistics

Total Valuation

Upstream Bio has a market cap or net worth of $537.67 million. The enterprise value is $197.43 million.

Market Cap537.67M
Enterprise Value 197.43M

Important Dates

The next estimated earnings date is Tuesday, May 5, 2026, before market open.

Earnings Date May 5, 2026
Ex-Dividend Date n/a

Share Statistics

Upstream Bio has 54.42 million shares outstanding. The number of shares has increased by 293.59% in one year.

Current Share Class 54.42M
Shares Outstanding 54.42M
Shares Change (YoY) +293.59%
Shares Change (QoQ) +0.29%
Owned by Insiders (%) 0.29%
Owned by Institutions (%) 72.43%
Float 34.59M

Valuation Ratios

PE Ratio n/a
Forward PE n/a
PS Ratio 188.39
Forward PS 297.07
PB Ratio 1.58
P/TBV Ratio 1.58
P/FCF Ratio n/a
P/OCF Ratio n/a
PEG Ratio n/a
Financial Ratio History

Enterprise Valuation

EV / Earnings n/a
EV / Sales 69.18
EV / EBITDA n/a
EV / EBIT n/a
EV / FCF n/a

Financial Position

The company has a current ratio of 26.15, with a Debt / Equity ratio of 0.00.

Current Ratio 26.15
Quick Ratio 25.56
Debt / Equity 0.00
Debt / EBITDA n/a
Debt / FCF n/a
Interest Coverage n/a

Financial Efficiency

Return on equity (ROE) is -35.43% and return on invested capital (ROIC) is -24.66%.

Return on Equity (ROE) -35.43%
Return on Assets (ROA) -23.99%
Return on Invested Capital (ROIC) -24.66%
Return on Capital Employed (ROCE) -47.12%
Weighted Average Cost of Capital (WACC) n/a
Revenue Per Employee $38,053
Profits Per Employee -$1.91M
Employee Count75
Asset Turnover 0.01
Inventory Turnover n/a

Taxes

Income Tax n/a
Effective Tax Rate n/a

Stock Price Statistics

The stock price has increased by +30.34% in the last 52 weeks.

Beta (5Y) n/a
52-Week Price Change +30.34%
50-Day Moving Average 11.29
200-Day Moving Average 18.98
Relative Strength Index (RSI) 46.79
Average Volume (20 Days) 806,386

Short Selling Information

The latest short interest is 3.44 million, so 6.31% of the outstanding shares have been sold short.

Short Interest 3.44M
Short Previous Month 4.75M
Short % of Shares Out 6.31%
Short % of Float 9.93%
Short Ratio (days to cover) 2.45

Income Statement

In the last 12 months, Upstream Bio had revenue of $2.85 million and -$143.44 million in losses. Loss per share was -$2.66.

Revenue2.85M
Gross Profit 2.85M
Operating Income -160.36M
Pretax Income -143.44M
Net Income -143.44M
EBITDA -160.17M
EBIT -160.36M
Loss Per Share -$2.66
Full Income Statement

Balance Sheet

The company has $341.51 million in cash and $1.27 million in debt, with a net cash position of $340.24 million or $6.25 per share.

Cash & Cash Equivalents 341.51M
Total Debt 1.27M
Net Cash 340.24M
Net Cash Per Share $6.25
Equity (Book Value) 339.77M
Book Value Per Share 6.26
Working Capital 338.35M
Full Balance Sheet

Cash Flow

In the last 12 months, operating cash flow was -$133.28 million and capital expenditures -$165,000, giving a free cash flow of -$133.44 million.

Operating Cash Flow -133.28M
Capital Expenditures -165,000
Depreciation & Amortization 188,000
Net Borrowing n/a
Free Cash Flow -133.44M
FCF Per Share -$2.45
Full Cash Flow Statement

Margins

Gross Margin 100.00%
Operating Margin -5,618.82%
Pretax Margin -5,026.03%
Profit Margin n/a
EBITDA Margin n/a
EBIT Margin n/a
FCF Margin n/a

Dividends & Yields

Upstream Bio does not appear to pay any dividends at this time.

Dividend Per Share n/a
Dividend Yield n/a
Dividend Growth (YoY) n/a
Years of Dividend Growth n/a
Payout Ratio n/a
Buyback Yield -293.59%
Shareholder Yield n/a
Earnings Yield -26.68%
FCF Yield -24.82%

Analyst Forecast

The average price target for Upstream Bio is $37.67, which is 281.28% higher than the current price. The consensus rating is "Buy".

Price Target $37.67
Price Target Difference 281.28%
Analyst Consensus Buy
Analyst Count 3
Revenue Growth Forecast (5Y) 100.60%
EPS Growth Forecast (5Y) 6.32%
Stock Forecasts

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value n/a
Lynch Upside n/a
Graham Number n/a
Graham Upside n/a

Stock Splits

This stock does not have any record of stock splits.

Last Split Date n/a
Split Type n/a
Split Ratio n/a

Scores

Upstream Bio has an Altman Z-Score of 32.81 and a Piotroski F-Score of 1.

Altman Z-Score 32.81
Piotroski F-Score 1