Ionis Pharmaceuticals, Inc. (IONS)

NASDAQ: IONS · Real-Time Price · USD

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74.30

+0.13 (0.18%)

At close: Oct 31, 2025, 4:00 PM EDT

75.49

+1.19 (1.60%)

After-hours: Oct 31, 2025, 7:14 PM EDT

Ionis Pharmaceuticals Income Statement

Financials in millions USD. Fiscal year is January - December.

Millions USD. Fiscal year is Jan - Dec.

Fiscal Year	TTM	FY 2024	FY 2023	FY 2022	FY 2021	FY 2020	2015 - 2019
Period Ending	Sep '25 Sep 30, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021	Dec '20 Dec 31, 2020	2015 - 2019
Revenue	966.96	705.14	787.65	587.37	810.46	729.26	Upgrade
Revenue Growth (YoY)	20.41%	-10.47%	34.10%	-27.53%	11.13%	-35.04%	Upgrade
Cost of Revenue	893.25	912.75	908.76	847.26	654.3	11.95	Upgrade
Gross Profit	73.71	-207.61	-121.11	-259.9	156.16	717.32	Upgrade
Selling, General & Admin	351.76	267.47	212.62	150.3	186.35	354.32	Upgrade
Research & Development	-	-	-	-	-	535.08	Upgrade
Operating Expenses	351.76	267.47	212.62	150.3	186.35	889.4	Upgrade
Operating Income	-278.05	-475.08	-333.73	-410.19	-30.19	-172.08	Upgrade
Interest Expense	-90.72	-90.45	-81.46	-8.12	-9.35	-9.51	Upgrade
Interest & Investment Income	101.95	107.02	89.04	25.33	10.04	30.56	Upgrade
Other Non Operating Income (Expenses)	1.24	1.34	0.87	-7.27	-1.13	-0.06	Upgrade
EBT Excluding Unusual Items	-265.58	-457.17	-325.28	-400.26	-30.62	-151.09	Upgrade
Gain (Loss) on Sale of Investments	6.86	-2.89	-1.91	-7.33	10.1	16.54	Upgrade
Gain (Loss) on Sale of Assets	-0.01	-0.01	-0.16	149.6	-	-	Upgrade
Other Unusual Items	-	-	-6.61	-	-8.63	-	Upgrade
Pretax Income	-258.72	-460.07	-333.97	-257.99	-29.15	-134.55	Upgrade
Income Tax Expense	-2.38	-6.17	32.32	11.74	-0.55	345.19	Upgrade
Earnings From Continuing Operations	-256.34	-453.9	-366.29	-269.72	-28.6	-479.74	Upgrade
Minority Interest in Earnings	-	-	-	-	-	35.48	Upgrade
Net Income	-256.34	-453.9	-366.29	-269.72	-28.6	-444.26	Upgrade
Net Income to Common	-256.34	-453.9	-366.29	-269.72	-28.6	-444.26	Upgrade
Shares Outstanding (Basic)	159	150	143	142	141	140	Upgrade
Shares Outstanding (Diluted)	159	150	143	142	141	140	Upgrade
Shares Change (YoY)	8.89%	4.42%	0.95%	0.59%	1.01%	-8.85%	Upgrade
EPS (Basic)	-1.61	-3.04	-2.56	-1.90	-0.20	-3.18	Upgrade
EPS (Diluted)	-1.61	-3.04	-2.56	-1.90	-0.20	-3.18	Upgrade
Free Cash Flow	-302.66	-546.23	-331.32	-290.09	18.84	0.77	Upgrade
Free Cash Flow Per Share	-1.91	-3.65	-2.31	-2.04	0.13	0.01	Upgrade
Gross Margin	7.62%	-29.44%	-15.38%	-44.25%	19.27%	98.36%	Upgrade
Operating Margin	-28.75%	-67.37%	-42.37%	-69.84%	-3.72%	-23.60%	Upgrade
Profit Margin	-26.51%	-64.37%	-46.50%	-45.92%	-3.53%	-60.92%	Upgrade
Free Cash Flow Margin	-31.30%	-77.46%	-42.06%	-49.39%	2.33%	0.11%	Upgrade
EBITDA	-266.8	-463.13	-320.88	-393.45	-12.35	-156.65	Upgrade
EBITDA Margin	-27.59%	-65.68%	-40.74%	-66.98%	-1.52%	-21.48%	Upgrade
D&A For EBITDA	11.25	11.95	12.85	16.74	17.84	15.43	Upgrade
EBIT	-278.05	-475.08	-333.73	-410.19	-30.19	-172.08	Upgrade
EBIT Margin	-28.75%	-67.37%	-42.37%	-69.84%	-3.72%	-23.60%	Upgrade
Revenue as Reported	966.96	705.14	787.65	587.37	810.46	729.26	Upgrade

Updated Oct 29, 2025. Source: S&P Global Market Intelligence. Standard template. Financial Sources.

SEC Filings: 10-K · 10-Q