Ionis Pharmaceuticals, Inc. (IONS)

Ionis Pharmaceuticals Cash Flow Statement

Financials in millions USD. Fiscal year is January - December.

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Mar 31, 2026	Dec 31, 2025	Dec 31, 2024	Dec 31, 2023	Dec 31, 2022	Dec 31, 2021
Net Income	-326.98	-381.39	-453.9	-366.29	-269.72	-28.6
Depreciation & Amortization	24.74	22.69	21.99	22.5	22.11	19.56
Stock-Based Compensation	147.43	133.87	130.2	105.81	100.26	120.68
Other Adjustments	-1.44	7.45	10.15	7.73	-134.59	32.98
Change in Receivables	-33.98	26.13	5.59	-72.06	36.36	14.31
Changes in Inventories	-14.35	-13.67	-5.07	-2.47	5.33	-2.84
Changes in Accounts Payable	7.51	-15.36	15.99	8.12	1.09	-6
Changes in Accrued Expenses	9.47	46.62	1.89	18.55	10.37	-26.92
Changes in Income Taxes Payable	2.75	2.68	-2.12	-4.1	6.21	-0.28
Changes in Unearned Revenue	-76.83	-69.73	-156.82	13.97	-71.25	-82.83
Changes in Other Operating Activities	-634.75	-27.88	-68.85	-39.27	19.46	-9.26
Operating Cash Flow	-910.63	-268.58	-500.95	-307.51	-274.37	30.8
Operating Cash Flow Growth	-	-	-	-	-	-14.19%
Capital Expenditures	-60.63	-51.44	-45.28	-23.81	-15.72	-11.96
Sale of Property, Plant & Equipment	-	-	-	-	254.08	-
Purchases of Intangible Assets	-6.48	-5.64	-5.06	-4.18	-4.38	-5.95
Purchases of Investments	-1,800	-1,919	-1,853	-1,771	-1,486	-1,131
Proceeds from Sale of Investments	1,956	1,698	1,769	1,585	989.15	1,344
Investing Cash Flow	88.59	-277.78	-134.03	-214.13	-262.64	194.91
Long-Term Debt Issued	-	770	-	1,075	-	632.5
Long-Term Debt Repaid	-0.18	-267.82	-44.67	-488.1	-10.95	-318.93
Net Long-Term Debt Issued (Repaid)	-0.18	502.19	-44.67	586.9	-10.95	313.57
Issuance of Common Stock	247.67	192.6	522.73	49.44	6.37	11.57
Repurchase of Common Stock	-	-	-	-	-50.69	-16.73
Net Common Stock Issued (Repurchased)	247.67	192.6	522.73	49.44	-44.31	-5.16
Other Financing Activities	-	-18.95	-	7.74	-0.03	-62.48
Financing Cash Flow	730.9	675.84	478.06	644.08	-55.3	245.93
Effect of Exchange Rate Changes on Cash and Cash Equivalents	0.33	0.7	-0.27	0.35	-0.42	-0.11
Net Cash Flow	-90.81	130.18	-157.19	122.79	-592.72	471.53
Free Cash Flow	-971.26	-320.03	-546.23	-331.32	-290.09	18.84
Free Cash Flow Growth	-	-	-	-	-	2340.93%
FCF Margin	-91.78%	-33.91%	-77.46%	-42.06%	-49.39%	2.33%
Free Cash Flow Per Share	-5.81	-2.00	-3.65	-2.31	-2.05	0.13
Levered Free Cash Flow	-1,069	14.7	-736.84	214.1	-303.08	164.45
Unlevered Free Cash Flow	-1,096	-489.57	-706.98	-394.47	-451.26	-150.14

Updated Apr 29, 2026. Data Source: Fiscal.ai. Standard template. Financial Sources.

SEC Filings: 10-K · 10-Q