Ionis Pharmaceuticals, Inc. (IONS)

NASDAQ: IONS · Real-Time Price · USD

81.80

+2.61 (3.30%)

At close: Jul 2, 2026, 4:00 PM EDT

81.78

-0.02 (-0.02%)

After-hours: Jul 2, 2026, 7:53 PM EDT

Ionis Pharmaceuticals Ratios and Metrics

Market cap in millions USD. Fiscal year is January - December.

Millions USD. Fiscal year is Jan - Dec.

Fiscal Year	Current	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Jul '26 Jul 2, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Market Cap	13,518	12,919	5,520	7,302	5,366	4,297
Market Cap Growth	131.06%	134.02%	-24.40%	36.09%	24.87%	-45.86%
Enterprise Value	14,151	12,283	4,630	6,416	4,740	3,430
Last Close Price	81.80	79.11	34.96	50.59	37.77	30.43
PS Ratio	12.78	13.69	7.83	9.27	9.13	5.30
PB Ratio	27.62	26.41	9.38	18.89	9.37	5.57
P/TBV Ratio	27.84	25.88	8.88	18.74	9.35	5.56
P/FCF Ratio	-	-	-	-	-	228.03
P/OCF Ratio	-	-	-	-	-	139.52
EV/Sales Ratio	13.37	13.02	6.57	8.15	8.07	4.23
EV/FCF Ratio	-	-	-	-	-	182.00
Debt / Equity Ratio	3.27	3.29	2.39	3.62	2.38	1.62
Debt / EBITDA Ratio	12.40	-	-	-	-	-
Debt / FCF Ratio	-	-	-	-	-	66.20
Net Debt / Equity Ratio	0.25	-1.30	-1.51	-2.29	-1.09	-1.12
Net Debt / EBITDA Ratio	0.74	1.77	1.97	2.68	1.61	81.64
Net Debt / FCF Ratio	-0.12	1.99	1.63	2.68	2.15	-46.03
Asset Turnover	0.30	0.29	0.24	0.29	0.23	0.32
Inventory Turnover	2.23	1.41	1.12	0.62	0.60	0.46
Quick Ratio	2.78	3.51	7.73	5.42	6.46	9.05
Current Ratio	4.10	3.83	8.47	5.90	7.07	9.75
Return on Equity (ROE)	25.20%	-70.80%	-93.10%	-76.34%	-40.12%	-3.78%
Return on Assets (ROA)	3.77%	-11.75%	-15.64%	-14.05%	-16.67%	-1.18%
Return on Invested Capital (ROIC)	10.92%	-49.50%	-90.17%	-78.36%	-106.75%	-5.63%
Return on Capital Employed (ROCE)	5.11%	-14.04%	-18.15%	-14.85%	-17.86%	-1.45%
FCF Yield	-	-	-	-	-	0.44%
Buyback Yield / Dilution	-5.71%	-7.02%	-4.42%	-0.95%	-0.59%	-1.01%
Total Shareholder Return	-5.71%	-7.02%	-4.42%	-0.95%	-0.59%	-1.01%

SEC Filings: 10-K · 10-Q