Ionis Pharmaceuticals, Inc. (IONS)

Ionis Pharmaceuticals Cash Flow Statement

Financials in millions USD. Fiscal year is January - December.

Fiscal Year	TTM	FY 2024	FY 2023	FY 2022	FY 2021	FY 2020
Period Ending	Jun 30, 2025	Dec 31, 2024	Dec 31, 2023	Dec 31, 2022	Dec 31, 2021	Dec 31, 2020
Net Income	-268.22	-453.9	-366.29	-269.72	-28.6	-444.26
Depreciation & Amortization	21.61	21.99	22.5	22.11	19.56	17.16
Other Amortization	6.64	6.69	6.33	5.37	4.96	3.26
Loss (Gain) From Sale of Assets	10.34	10.44	18.47	-147.57	2.71	1.95
Loss (Gain) From Sale of Investments	-9.41	-34.84	-27.3	7.61	16.68	-5.02
Stock-Based Compensation	127.54	130.2	105.81	100.26	120.68	230.12
Other Operating Activities	20.42	27.87	10.22	-	8.63	306.25
Change in Accounts Receivable	-25.32	5.59	-72.06	36.36	14.31	-13.17
Change in Inventory	-17.24	-5.07	-2.47	5.33	-2.84	-1.26
Change in Accounts Payable	12.75	15.99	8.12	1.09	-6	-2.76
Change in Unearned Revenue	-81.76	-156.82	13.97	-71.25	-82.83	-75.91
Change in Income Taxes	-0.2	-2.12	-4.1	6.21	-0.28	-31.28
Change in Other Net Operating Assets	-27.72	-66.96	-20.72	29.83	-36.18	50.82
Operating Cash Flow	-230.57	-500.95	-307.51	-274.37	30.8	35.89
Operating Cash Flow Growth	-	-	-	-	-14.19%	-89.61%
Capital Expenditures	-59.44	-45.28	-23.81	-15.72	-11.96	-35.12
Sale (Purchase) of Intangibles	7.59	-5.06	-4.21	-4.38	-5.95	-5.93
Sale (Purchase) of Real Estate	-	-	0.02	254.08	-	-
Investment in Securities	-170.34	-83.69	-186.14	-496.62	212.81	315.53
Investing Cash Flow	-222.19	-134.03	-214.13	-262.64	194.91	274.48
Long-Term Debt Issued	-	-	575	-	632.5	-
Long-Term Debt Repaid	-	-44.67	-488.1	-50.69	-318.93	-
Net Debt Issued (Repaid)	-44.68	-44.67	86.9	-50.69	313.57	-
Issuance of Common Stock	500.05	522.73	49.44	6.37	11.57	52.04
Repurchase of Common Stock	-	-	-	-10.95	-16.73	-103.96
Other Financing Activities	-	-	507.74	-0.03	-62.48	-544.69
Financing Cash Flow	455.38	478.06	644.08	-55.3	245.93	-596.61
Foreign Exchange Rate Adjustments	0.69	-0.27	0.35	-0.42	-0.11	0.62
Net Cash Flow	3.31	-157.19	122.79	-592.72	471.53	-285.62
Free Cash Flow	-290	-546.23	-331.32	-290.09	18.84	0.77
Free Cash Flow Growth	-	-	-	-	2340.93%	-99.76%
Free Cash Flow Margin	-30.72%	-77.46%	-42.06%	-49.39%	2.33%	0.11%
Free Cash Flow Per Share	-1.86	-3.65	-2.31	-2.04	0.13	0.01
Cash Interest Paid	10.51	10.87	6.51	2.9	4.78	6.25
Cash Income Tax Paid	-	-5.62	48.33	5.01	0.04	25.86
Levered Free Cash Flow	-168.63	-352.83	-161.03	-80.22	76.54	88.04
Unlevered Free Cash Flow	-118.24	-302.98	-116.45	-80.51	77.42	90.73
Change in Working Capital	-139.5	-209.39	-77.26	7.57	-113.82	-73.56

Updated Jul 30, 2025. Source: S&P Global Market Intelligence. Standard template. Financial Sources.

SEC Filings: 10-K · 10-Q