Ionis Pharmaceuticals, Inc. (IONS)

Ionis Pharmaceuticals Ratios and Metrics

Market cap in millions USD. Fiscal year is January - December.

Fiscal Year	Current	FY 2023	FY 2022	FY 2021	FY 2020	FY 2019
Period Ending	Jan 31, 2025	Dec 31, 2023	Dec 31, 2022	Dec 31, 2021	Dec 31, 2020	Dec 31, 2019
Market Capitalization	5,037	7,258	5,365	4,297	7,906	8,497
Market Cap Growth	-2.94%	35.28%	24.86%	-45.65%	-6.97%	14.26%
Enterprise Value	4,541	6,991	4,631	3,606	6,615	7,112
Last Close Price	31.90	50.59	37.77	30.43	56.54	60.41
PE Ratio	-	-	-	-	-	30.29
Forward PE	-	-	-	-	-	43.66
PS Ratio	5.80	9.22	9.13	5.30	10.84	7.57
PB Ratio	7.60	18.77	9.37	5.57	10.64	5.04
P/TBV Ratio	9.53	18.77	9.37	5.57	11.05	5.88
P/FCF Ratio	-	-	-	228.03	10240.41	27.00
P/OCF Ratio	-	-	-	139.52	220.26	24.59
EV/Sales Ratio	5.65	8.88	7.88	4.45	9.07	6.34
EV/EBITDA Ratio	-	-	-	-	-	18.59
EV/EBIT Ratio	-	-	-	-	-	19.32
EV/FCF Ratio	-	-	-	191.38	8569.00	22.60
Debt / Equity Ratio	3.01	5.09	2.39	1.62	1.26	0.47
Debt / EBITDA Ratio	-	-	-	-	-	2.04
Debt / FCF Ratio	-	-	-	66.39	1217.15	2.50
Asset Turnover	0.27	0.29	0.23	0.32	0.26	0.38
Inventory Turnover	33.95	35.95	36.09	27.86	27.16	34.96
Quick Ratio	8.24	5.43	6.49	9.13	3.30	9.42
Current Ratio	8.91	5.90	7.07	9.75	3.56	9.97
Return on Equity (ROE)	-73.38%	-76.34%	-40.12%	-3.78%	-39.52%	20.01%
Return on Assets (ROA)	-7.25%	-7.51%	-9.92%	-0.69%	-3.78%	7.80%
Return on Capital (ROIC)	-8.81%	-9.66%	-12.87%	-0.93%	-5.12%	10.69%
Return on Capital Employed (ROCE)	-	-	-	-	-	12.44%
Earnings Yield	-7.12%	-5.05%	-5.03%	-0.67%	-5.62%	3.27%
FCF Yield	-7.36%	-4.56%	-5.41%	0.44%	0.01%	3.70%
Buyback Yield / Dilution	-2.19%	-0.95%	-0.59%	-1.01%	8.85%	-14.25%
Total Shareholder Return	-2.19%	-0.95%	-0.59%	-1.01%	8.85%	-14.25%

Source: S&P Capital IQ. Standard template. Financial Sources.