Ionis Pharmaceuticals Statistics
Total Valuation
IONS has a market cap or net worth of $12.03 billion. The enterprise value is $11.85 billion.
Important Dates
The last earnings date was Wednesday, October 29, 2025, before market open.
| Earnings Date | Oct 29, 2025 |
| Ex-Dividend Date | n/a |
Share Statistics
IONS has 161.97 million shares outstanding. The number of shares has increased by 8.89% in one year.
| Current Share Class | 161.97M |
| Shares Outstanding | 161.97M |
| Shares Change (YoY) | +8.89% |
| Shares Change (QoQ) | -12.38% |
| Owned by Insiders (%) | 0.76% |
| Owned by Institutions (%) | 104.59% |
| Float | 160.67M |
Valuation Ratios
| PE Ratio | n/a |
| Forward PE | n/a |
| PS Ratio | 12.21 |
| Forward PS | 15.53 |
| PB Ratio | 19.37 |
| P/TBV Ratio | 19.47 |
| P/FCF Ratio | n/a |
| P/OCF Ratio | n/a |
| PEG Ratio | n/a |
Financial Ratio HistoryEnterprise Valuation
| EV / Earnings | n/a |
| EV / Sales | 12.26 |
| EV / EBITDA | n/a |
| EV / EBIT | n/a |
| EV / FCF | n/a |
Financial Position
The company has a current ratio of 2.79, with a Debt / Equity ratio of 3.33.
| Current Ratio | 2.79 |
| Quick Ratio | 2.51 |
| Debt / Equity | 3.33 |
| Debt / EBITDA | n/a |
| Debt / FCF | n/a |
| Interest Coverage | -3.07 |
Financial Efficiency
Return on equity (ROE) is -40.04% and return on invested capital (ROIC) is -6.52%.
| Return on Equity (ROE) | -40.04% |
| Return on Assets (ROA) | -5.68% |
| Return on Invested Capital (ROIC) | -6.52% |
| Return on Capital Employed (ROCE) | -13.06% |
| Revenue Per Employee | $904,543 |
| Profits Per Employee | -$239,796 |
| Employee Count | 1,069 |
| Asset Turnover | 0.32 |
| Inventory Turnover | 45.90 |
Taxes
| Income Tax | -2.38M |
| Effective Tax Rate | n/a |
Stock Price Statistics
The stock price has increased by +89.25% in the last 52 weeks. The beta is 0.33, so IONS's price volatility has been lower than the market average.
| Beta (5Y) | 0.33 |
| 52-Week Price Change | +89.25% |
| 50-Day Moving Average | 63.97 |
| 200-Day Moving Average | 42.25 |
| Relative Strength Index (RSI) | 69.92 |
| Average Volume (20 Days) | 2,041,509 |
Short Selling Information
The latest short interest is 13.70 million, so 8.46% of the outstanding shares have been sold short.
| Short Interest | 13.70M |
| Short Previous Month | 12.28M |
| Short % of Shares Out | 8.46% |
| Short % of Float | 8.53% |
| Short Ratio (days to cover) | 6.34 |
Income Statement
In the last 12 months, IONS had revenue of $966.96 million and -$256.34 million in losses. Loss per share was -$1.61.
| Revenue | 966.96M |
| Gross Profit | 73.71M |
| Operating Income | -278.05M |
| Pretax Income | -258.72M |
| Net Income | -256.34M |
| EBITDA | -266.80M |
| EBIT | -278.05M |
| Loss Per Share | -$1.61 |
Full Income StatementBalance Sheet
The company has $2.24 billion in cash and $2.06 billion in debt, giving a net cash position of $183.95 million or $1.14 per share.
| Cash & Cash Equivalents | 2.24B |
| Total Debt | 2.06B |
| Net Cash | 183.95M |
| Net Cash Per Share | $1.14 |
| Equity (Book Value) | 617.97M |
| Book Value Per Share | 3.84 |
| Working Capital | 1.62B |
Full Balance SheetCash Flow
In the last 12 months, operating cash flow was -$247.01 million and capital expenditures -$55.65 million, giving a free cash flow of -$302.66 million.
| Operating Cash Flow | -247.01M |
| Capital Expenditures | -55.65M |
| Free Cash Flow | -302.66M |
| FCF Per Share | -$1.87 |
Full Cash Flow StatementMargins
Gross margin is 7.62%, with operating and profit margins of -28.75% and -26.51%.
| Gross Margin | 7.62% |
| Operating Margin | -28.75% |
| Pretax Margin | -26.76% |
| Profit Margin | -26.51% |
| EBITDA Margin | -27.59% |
| EBIT Margin | -28.75% |
| FCF Margin | n/a |
Dividends & Yields
IONS does not appear to pay any dividends at this time.
| Dividend Per Share | n/a |
| Dividend Yield | n/a |
| Dividend Growth (YoY) | n/a |
| Years of Dividend Growth | n/a |
| Payout Ratio | n/a |
| Buyback Yield | -8.89% |
| Shareholder Yield | -8.89% |
| Earnings Yield | -2.13% |
| FCF Yield | -2.51% |
Dividend DetailsAnalyst Forecast
The average price target for IONS is $79.67, which is 7.23% higher than the current price. The consensus rating is "Strong Buy".
| Price Target | $79.67 |
| Price Target Difference | 7.23% |
| Analyst Consensus | Strong Buy |
| Analyst Count | 21 |
| Revenue Growth Forecast (5Y) | 28.01% |
| EPS Growth Forecast (5Y) | n/a |
Stock ForecastsFair Value
There are several formulas that can be used to estimate the intrinsic value of a stock.
| Lynch Fair Value | n/a |
| Lynch Upside | n/a |
| Graham Number | n/a |
| Graham Upside | n/a |
Stock Splits
This stock does not have any record of stock splits.
| Last Split Date | n/a |
| Split Type | n/a |
| Split Ratio | n/a |
Scores
IONS has an Altman Z-Score of 1.05 and a Piotroski F-Score of 4. A Z-score under 3 suggests an increased risk of bankruptcy.
| Altman Z-Score | 1.05 |
| Piotroski F-Score | 4 |
