Ionis Pharmaceuticals, Inc. (IONS)
NASDAQ: IONS · Real-Time Price · USD
69.97
-0.30 (-0.43%)
At close: Oct 10, 2025, 4:00 PM EDT
70.42
+0.45 (0.64%)
After-hours: Oct 10, 2025, 7:59 PM EDT

Ionis Pharmaceuticals Statistics

Total Valuation

IONS has a market cap or net worth of $11.15 billion. The enterprise value is $10.84 billion.

Market Cap11.15B
Enterprise Value 10.84B

Important Dates

The next estimated earnings date is Wednesday, November 5, 2025, before market open.

Earnings Date Nov 5, 2025
Ex-Dividend Date n/a

Share Statistics

IONS has 159.39 million shares outstanding. The number of shares has increased by 7.96% in one year.

Current Share Class 159.39M
Shares Outstanding 159.39M
Shares Change (YoY) +7.96%
Shares Change (QoQ) +14.87%
Owned by Insiders (%) 0.78%
Owned by Institutions (%) 106.03%
Float 158.08M

Valuation Ratios

PE Ratio n/a
Forward PE n/a
PS Ratio 11.57
Forward PS 16.53
PB Ratio 17.63
P/TBV Ratio 17.65
P/FCF Ratio n/a
P/OCF Ratio n/a
PEG Ratio n/a
Financial Ratio History

Enterprise Valuation

EV / Earnings n/a
EV / Sales 11.49
EV / EBITDA n/a
EV / EBIT n/a
EV / FCF n/a

Financial Position

The company has a current ratio of 2.87, with a Debt / Equity ratio of 3.14.

Current Ratio 2.87
Quick Ratio 2.61
Debt / Equity 3.14
Debt / EBITDA n/a
Debt / FCF n/a
Interest Coverage -2.92

Financial Efficiency

Return on equity (ROE) is -59.91% and return on invested capital (ROIC) is -6.85%.

Return on Equity (ROE) -59.91%
Return on Assets (ROA) -5.87%
Return on Invested Capital (ROIC) -6.85%
Return on Capital Employed (ROCE) -12.77%
Revenue Per Employee $883,115
Profits Per Employee -$250,904
Employee Count1,069
Asset Turnover 0.33
Inventory Turnover 48.06

Taxes

Income Tax -6.22M
Effective Tax Rate n/a

Stock Price Statistics

The stock price has increased by +83.84% in the last 52 weeks. The beta is 0.33, so IONS's price volatility has been lower than the market average.

Beta (5Y) 0.33
52-Week Price Change +83.84%
50-Day Moving Average 54.98
200-Day Moving Average 39.42
Relative Strength Index (RSI) 79.22
Average Volume (20 Days) 2,129,119

Short Selling Information

The latest short interest is 12.28 million, so 7.70% of the outstanding shares have been sold short.

Short Interest 12.28M
Short Previous Month 11.97M
Short % of Shares Out 7.70%
Short % of Float 7.77%
Short Ratio (days to cover) 3.69

Income Statement

In the last 12 months, IONS had revenue of $944.05 million and -$268.22 million in losses. Loss per share was -$1.73.

Revenue944.05M
Gross Profit 50.07M
Operating Income -266.52M
Pretax Income -274.43M
Net Income -268.22M
EBITDA -255.17M
EBIT -266.52M
Loss Per Share -$1.73
Full Income Statement

Balance Sheet

The company has $2.29 billion in cash and $1.98 billion in debt, giving a net cash position of $308.97 million or $1.94 per share.

Cash & Cash Equivalents 2.29B
Total Debt 1.98B
Net Cash 308.97M
Net Cash Per Share $1.94
Equity (Book Value) 631.72M
Book Value Per Share 3.97
Working Capital 1.68B
Full Balance Sheet

Cash Flow

In the last 12 months, operating cash flow was -$230.57 million and capital expenditures -$59.44 million, giving a free cash flow of -$290.00 million.

Operating Cash Flow -230.57M
Capital Expenditures -59.44M
Free Cash Flow -290.00M
FCF Per Share -$1.82
Full Cash Flow Statement

Margins

Gross margin is 5.30%, with operating and profit margins of -28.23% and -28.41%.

Gross Margin 5.30%
Operating Margin -28.23%
Pretax Margin -29.07%
Profit Margin -28.41%
EBITDA Margin -27.03%
EBIT Margin -28.23%
FCF Margin n/a

Dividends & Yields

IONS does not appear to pay any dividends at this time.

Dividend Per Share n/a
Dividend Yield n/a
Dividend Growth (YoY) n/a
Years of Dividend Growth n/a
Payout Ratio n/a
Buyback Yield -7.95%
Shareholder Yield -7.95%
Earnings Yield -2.40%
FCF Yield -2.60%
Dividend Details

Analyst Forecast

The average price target for IONS is $75.35, which is 7.69% higher than the current price. The consensus rating is "Strong Buy".

Price Target $75.35
Price Target Difference 7.69%
Analyst Consensus Strong Buy
Analyst Count 20
Revenue Growth Forecast (5Y) 28.01%
EPS Growth Forecast (5Y) n/a
Stock Forecasts

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value n/a
Lynch Upside n/a
Graham Number n/a
Graham Upside n/a

Stock Splits

This stock does not have any record of stock splits.

Last Split Date n/a
Split Type n/a
Split Ratio n/a

Scores

IONS has an Altman Z-Score of 1.11 and a Piotroski F-Score of 4. A Z-score under 3 suggests an increased risk of bankruptcy.

Altman Z-Score 1.11
Piotroski F-Score 4