Ionis Pharmaceuticals, Inc. (IONS)
NASDAQ: IONS · Real-Time Price · USD
79.55
-2.41 (-2.94%)
Mar 3, 2026, 2:51 PM EST - Market open

Ionis Pharmaceuticals Statistics

Total Valuation

IONS has a market cap or net worth of $13.14 billion. The enterprise value is $13.00 billion.

Market Cap13.14B
Enterprise Value 13.00B

Important Dates

The last earnings date was Wednesday, February 25, 2026, before market open.

Earnings Date Feb 25, 2026
Ex-Dividend Date n/a

Share Statistics

IONS has 165.19 million shares outstanding. The number of shares has increased by 7.02% in one year.

Current Share Class 165.19M
Shares Outstanding 165.19M
Shares Change (YoY) +7.02%
Shares Change (QoQ) +1.40%
Owned by Insiders (%) 0.81%
Owned by Institutions (%) 103.83%
Float 163.79M

Valuation Ratios

PE Ratio n/a
Forward PE n/a
PS Ratio 13.84
Forward PS 14.66
PB Ratio 27.37
P/TBV Ratio 26.70
P/FCF Ratio n/a
P/OCF Ratio n/a
PEG Ratio n/a
Financial Ratio History

Enterprise Valuation

EV / Earnings n/a
EV / Sales 13.77
EV / EBITDA n/a
EV / EBIT n/a
EV / FCF n/a

Financial Position

The company has a current ratio of 3.83, with a Debt / Equity ratio of 5.35.

Current Ratio 3.83
Quick Ratio 3.51
Debt / Equity 5.35
Debt / EBITDA n/a
Debt / FCF n/a
Interest Coverage -4.22

Financial Efficiency

Return on equity (ROE) is -70.80% and return on invested capital (ROIC) is -90.05%.

Return on Equity (ROE) -70.80%
Return on Assets (ROA) -7.31%
Return on Invested Capital (ROIC) -90.05%
Return on Capital Employed (ROCE) -13.92%
Weighted Average Cost of Capital (WACC) 5.67%
Revenue Per Employee $882,798
Profits Per Employee -$356,770
Employee Count1,402
Asset Turnover 0.29
Inventory Turnover 82.58

Taxes

In the past 12 months, IONS has paid $1.79 million in taxes.

Income Tax 1.79M
Effective Tax Rate n/a

Stock Price Statistics

The stock price has increased by +139.98% in the last 52 weeks. The beta is 0.36, so IONS's price volatility has been lower than the market average.

Beta (5Y) 0.36
52-Week Price Change +139.98%
50-Day Moving Average 81.38
200-Day Moving Average 62.00
Relative Strength Index (RSI) 42.86
Average Volume (20 Days) 2,125,500

Short Selling Information

The latest short interest is 15.49 million, so 9.38% of the outstanding shares have been sold short.

Short Interest 15.49M
Short Previous Month 15.54M
Short % of Shares Out 9.38%
Short % of Float 9.46%
Short Ratio (days to cover) 6.96

Income Statement

In the last 12 months, IONS had revenue of $943.71 million and -$381.39 million in losses. Loss per share was -$2.38.

Revenue943.71M
Gross Profit 12.18M
Operating Income -381.68M
Pretax Income -379.60M
Net Income -381.39M
EBITDA -369.24M
EBIT -381.68M
Loss Per Share -$2.38
Full Income Statement

Balance Sheet

The company has $2.68 billion in cash and $2.62 billion in debt, with a net cash position of $64.58 million or $0.39 per share.

Cash & Cash Equivalents 2.68B
Total Debt 2.62B
Net Cash 64.58M
Net Cash Per Share $0.39
Equity (Book Value) 489.09M
Book Value Per Share 2.99
Working Capital 2.21B
Full Balance Sheet

Cash Flow

In the last 12 months, operating cash flow was -$268.58 million and capital expenditures -$51.44 million, giving a free cash flow of -$320.03 million.

Operating Cash Flow -268.58M
Capital Expenditures -51.44M
Free Cash Flow -320.03M
FCF Per Share -$1.94
Full Cash Flow Statement

Margins

Gross margin is 1.29%, with operating and profit margins of -40.45% and -40.41%.

Gross Margin 1.29%
Operating Margin -40.45%
Pretax Margin -40.22%
Profit Margin -40.41%
EBITDA Margin -39.13%
EBIT Margin -40.45%
FCF Margin n/a

Dividends & Yields

IONS does not appear to pay any dividends at this time.

Dividend Per Share n/a
Dividend Yield n/a
Dividend Growth (YoY) n/a
Years of Dividend Growth n/a
Payout Ratio n/a
Buyback Yield -7.02%
Shareholder Yield -7.02%
Earnings Yield -2.92%
FCF Yield -2.45%
Dividend Details

Analyst Forecast

The average price target for IONS is $85.91, which is 8.00% higher than the current price. The consensus rating is "Strong Buy".

Price Target $85.91
Price Target Difference 8.00%
Analyst Consensus Strong Buy
Analyst Count 22
Revenue Growth Forecast (5Y) 30.44%
EPS Growth Forecast (5Y) n/a
Stock Forecasts

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value n/a
Lynch Upside n/a
Graham Number n/a
Graham Upside n/a

Stock Splits

This stock does not have any record of stock splits.

Last Split Date n/a
Split Type n/a
Split Ratio n/a

Scores

IONS has an Altman Z-Score of 1.13 and a Piotroski F-Score of 3. A Z-score under 3 suggests an increased risk of bankruptcy.

Altman Z-Score 1.13
Piotroski F-Score 3