Ionis Pharmaceuticals, Inc. (IONS)
NASDAQ: IONS · Real-Time Price · USD
42.69
-0.55 (-1.26%)
At close: Aug 22, 2025, 4:00 PM
43.00
+0.31 (0.73%)
After-hours: Aug 22, 2025, 5:23 PM EDT

Ionis Pharmaceuticals Statistics

Total Valuation

IONS has a market cap or net worth of $6.80 billion. The enterprise value is $6.50 billion.

Market Cap6.80B
Enterprise Value 6.50B

Important Dates

The last earnings date was Wednesday, July 30, 2025, before market open.

Earnings Date Jul 30, 2025
Ex-Dividend Date n/a

Share Statistics

IONS has 159.39 million shares outstanding. The number of shares has increased by 7.96% in one year.

Current Share Class 159.39M
Shares Outstanding 159.39M
Shares Change (YoY) +7.96%
Shares Change (QoQ) +14.87%
Owned by Insiders (%) 0.84%
Owned by Institutions (%) 105.37%
Float 157.97M

Valuation Ratios

PE Ratio n/a
Forward PE n/a
PS Ratio 7.06
Forward PS 10.07
PB Ratio 10.76
P/TBV Ratio 10.77
P/FCF Ratio n/a
P/OCF Ratio n/a
PEG Ratio n/a
Financial Ratio History

Enterprise Valuation

EV / Earnings n/a
EV / Sales 6.88
EV / EBITDA n/a
EV / EBIT n/a
EV / FCF n/a

Financial Position

The company has a current ratio of 2.87, with a Debt / Equity ratio of 3.14.

Current Ratio 2.87
Quick Ratio 2.61
Debt / Equity 3.14
Debt / EBITDA n/a
Debt / FCF n/a
Interest Coverage -2.92

Financial Efficiency

Return on equity (ROE) is -59.91% and return on invested capital (ROIC) is -6.85%.

Return on Equity (ROE) -59.91%
Return on Assets (ROA) -5.87%
Return on Invested Capital (ROIC) -6.85%
Return on Capital Employed (ROCE) -12.77%
Revenue Per Employee $883,115
Profits Per Employee -$250,904
Employee Count1,069
Asset Turnover 0.33
Inventory Turnover 48.06

Taxes

Income Tax -6.22M
Effective Tax Rate n/a

Stock Price Statistics

The stock price has decreased by -11.39% in the last 52 weeks. The beta is 0.25, so IONS's price volatility has been lower than the market average.

Beta (5Y) 0.25
52-Week Price Change -11.39%
50-Day Moving Average 41.20
200-Day Moving Average 35.32
Relative Strength Index (RSI) 53.32
Average Volume (20 Days) 2,215,499

Short Selling Information

The latest short interest is 11.58 million, so 7.27% of the outstanding shares have been sold short.

Short Interest 11.58M
Short Previous Month 12.89M
Short % of Shares Out 7.27%
Short % of Float 7.33%
Short Ratio (days to cover) 5.85

Income Statement

In the last 12 months, IONS had revenue of $944.05 million and -$268.22 million in losses. Loss per share was -$1.73.

Revenue944.05M
Gross Profit 50.07M
Operating Income -266.52M
Pretax Income -352.50M
Net Income -268.22M
EBITDA -255.17M
EBIT -266.52M
Loss Per Share -$1.73
Full Income Statement

Balance Sheet

The company has $2.29 billion in cash and $1.98 billion in debt, giving a net cash position of $308.97 million or $1.94 per share.

Cash & Cash Equivalents 2.29B
Total Debt 1.98B
Net Cash 308.97M
Net Cash Per Share $1.94
Equity (Book Value) 631.72M
Book Value Per Share 3.97
Working Capital 1.68B
Full Balance Sheet

Cash Flow

In the last 12 months, operating cash flow was -$230.57 million and capital expenditures -$59.44 million, giving a free cash flow of -$290.00 million.

Operating Cash Flow -230.57M
Capital Expenditures -59.44M
Free Cash Flow -290.00M
FCF Per Share -$1.82
Full Cash Flow Statement

Margins

Gross margin is 5.30%, with operating and profit margins of -28.23% and -28.41%.

Gross Margin 5.30%
Operating Margin -28.23%
Pretax Margin -29.07%
Profit Margin -28.41%
EBITDA Margin -27.03%
EBIT Margin -28.23%
FCF Margin n/a

Dividends & Yields

IONS does not appear to pay any dividends at this time.

Dividend Per Share n/a
Dividend Yield n/a
Dividend Growth (YoY) n/a
Years of Dividend Growth n/a
Payout Ratio n/a
Buyback Yield -7.95%
Shareholder Yield -7.95%
Earnings Yield -3.94%
FCF Yield -4.26%
Dividend Details

Analyst Forecast

The average price target for IONS is $60.13, which is 40.85% higher than the current price. The consensus rating is "Buy".

Price Target $60.13
Price Target Difference 40.85%
Analyst Consensus Buy
Analyst Count 15
Revenue Growth Forecast (5Y) 26.21%
EPS Growth Forecast (5Y) n/a
Stock Forecasts

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value n/a
Lynch Upside n/a
Graham Number n/a
Graham Upside n/a

Stock Splits

This stock does not have any record of stock splits.

Last Split Date n/a
Split Type n/a
Split Ratio n/a

Scores

IONS has an Altman Z-Score of 1.11 and a Piotroski F-Score of 4. A Z-score under 3 suggests an increased risk of bankruptcy.

Altman Z-Score 1.11
Piotroski F-Score 4