Spyre Therapeutics, Inc. (SYRE)

NASDAQ: SYRE · Real-Time Price · USD

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32.75

+0.77 (2.41%)

At close: Feb 2, 2026, 4:00 PM EST

32.75

0.00 (0.00%)

After-hours: Feb 2, 2026, 4:00 PM EST

Spyre Therapeutics Income Statement

Financials in millions USD. Fiscal year is January - December.

Millions USD. Fiscal year is Jan - Dec.

Fiscal Year	TTM	FY 2024	FY 2023	FY 2022	FY 2021	FY 2020
Period Ending	Sep '25 Sep 30, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021	Dec '20 Dec 31, 2020
Revenue	-	-	0.89	2.33	18.74	-
Revenue Growth (YoY)	-	-	-61.96%	-87.57%	-	-
Cost of Revenue	177.5	162.79	84.05	58.58	57.07	59.64
Gross Profit	-177.5	-162.79	-83.16	-56.25	-38.33	-59.64
Selling, General & Admin	46.15	45.78	34.45	28.53	27.32	21.84
Operating Expenses	46.15	45.78	34.45	28.53	27.32	21.84
Operating Income	-223.64	-208.57	-117.61	-84.78	-65.65	-81.48
Interest & Investment Income	23.52	21.31	6.15	0.84	0.11	0.59
Other Non Operating Income (Expenses)	41.14	-20.71	-102.66	-0.01	-0.12	-0.01
EBT Excluding Unusual Items	-158.98	-207.97	-214.13	-83.95	-65.66	-80.89
Merger & Restructuring Charges	-	-	-10.95	-	-	-
Gain (Loss) on Sale of Assets	10	-	16.45	-	-	-
Pretax Income	-148.98	-207.97	-338.82	-83.95	-65.66	-80.89
Income Tax Expense	-0.01	0.05	-0.03	-0.14	0.14	-
Net Income	-148.97	-208.02	-338.79	-83.82	-65.8	-80.89
Preferred Dividends & Other Adjustments	-30.59	-58.46	-243.91	-	-	-
Net Income to Common	-118.38	-149.56	-94.88	-83.82	-65.8	-80.89
Shares Outstanding (Basic)	59	47	7	3	3	2
Shares Outstanding (Diluted)	59	47	7	3	3	2
Shares Change (YoY)	59.15%	581.85%	104.59%	28.19%	23.18%	67.05%
EPS (Basic)	-2.00	-3.18	-13.76	-24.86	-25.02	-37.89
EPS (Diluted)	-2.00	-3.18	-13.76	-24.86	-25.02	-37.89
Free Cash Flow	-161.87	-157.41	-99.91	-80.18	-54.29	-80.06
Free Cash Flow Per Share	-2.74	-3.35	-14.49	-23.78	-20.64	-37.50
Gross Margin	-	-	-	-	-204.55%	-
Operating Margin	-	-	-13274.49%	-3640.23%	-350.33%	-
Profit Margin	-	-	-10709.14%	-3598.76%	-351.14%	-
Free Cash Flow Margin	-	-	-11276.52%	-3442.76%	-289.71%	-
EBITDA	-	-207.82	-116.87	-83.21	-64.07	-80.49
D&A For EBITDA	-	0.74	0.74	1.57	1.58	1
EBIT	-223.64	-208.57	-117.61	-84.78	-65.65	-81.48
Revenue as Reported	-	-	0.89	2.33	18.74	-

Updated Sep 30, 2025. Source: S&P Global Market Intelligence. Standard template. Financial Sources.

SEC Filings: 10-K · 10-Q