Spyre Therapeutics, Inc. (SYRE)

NASDAQ: SYRE · Real-Time Price · USD

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22.39

-0.46 (-2.01%)

At close: Nov 6, 2025, 4:00 PM EST

21.26

-1.13 (-5.05%)

Pre-market: Nov 7, 2025, 8:42 AM EST

Spyre Therapeutics Income Statement

Financials in millions USD. Fiscal year is January - December.

Millions USD. Fiscal year is Jan - Dec.

Fiscal Year	TTM	FY 2024	FY 2023	FY 2022	FY 2021	FY 2020	2015 - 2019
Period Ending	Sep '25 Sep 30, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021	Dec '20 Dec 31, 2020	2015 - 2019
Revenue	-	-	0.89	2.33	18.74	-	Upgrade
Revenue Growth (YoY)	-	-	-61.96%	-87.57%	-	-	Upgrade
Cost of Revenue	177.5	162.79	84.05	58.58	57.07	59.64	Upgrade
Gross Profit	-177.5	-162.79	-83.16	-56.25	-38.33	-59.64	Upgrade
Selling, General & Admin	46.15	45.78	34.45	28.53	27.32	21.84	Upgrade
Operating Expenses	46.15	45.78	34.45	28.53	27.32	21.84	Upgrade
Operating Income	-223.64	-208.57	-117.61	-84.78	-65.65	-81.48	Upgrade
Interest & Investment Income	23.52	21.31	6.15	0.84	0.11	0.59	Upgrade
Other Non Operating Income (Expenses)	41.14	-20.71	-102.66	-0.01	-0.12	-0.01	Upgrade
EBT Excluding Unusual Items	-158.98	-207.97	-214.13	-83.95	-65.66	-80.89	Upgrade
Merger & Restructuring Charges	-	-	-10.95	-	-	-	Upgrade
Gain (Loss) on Sale of Assets	10	-	16.45	-	-	-	Upgrade
Pretax Income	-148.98	-207.97	-338.82	-83.95	-65.66	-80.89	Upgrade
Income Tax Expense	-0.01	0.05	-0.03	-0.14	0.14	-	Upgrade
Net Income	-148.97	-208.02	-338.79	-83.82	-65.8	-80.89	Upgrade
Preferred Dividends & Other Adjustments	-30.59	-58.46	-243.91	-	-	-	Upgrade
Net Income to Common	-118.38	-149.56	-94.88	-83.82	-65.8	-80.89	Upgrade
Shares Outstanding (Basic)	59	47	7	3	3	2	Upgrade
Shares Outstanding (Diluted)	59	47	7	3	3	2	Upgrade
Shares Change (YoY)	59.15%	581.85%	104.59%	28.19%	23.18%	67.05%	Upgrade
EPS (Basic)	-2.00	-3.18	-13.76	-24.86	-25.02	-37.89	Upgrade
EPS (Diluted)	-2.00	-3.18	-13.76	-24.86	-25.02	-37.89	Upgrade
Free Cash Flow	-161.87	-157.41	-99.91	-80.18	-54.29	-80.06	Upgrade
Free Cash Flow Per Share	-2.74	-3.35	-14.49	-23.78	-20.64	-37.50	Upgrade
Gross Margin	-	-	-	-	-204.55%	-	Upgrade
Operating Margin	-	-	-13274.49%	-3640.23%	-350.33%	-	Upgrade
Profit Margin	-	-	-10709.14%	-3598.76%	-351.14%	-	Upgrade
Free Cash Flow Margin	-	-	-11276.52%	-3442.76%	-289.71%	-	Upgrade
EBITDA	-	-207.82	-116.87	-83.21	-64.07	-80.49	Upgrade
D&A For EBITDA	-	0.74	0.74	1.57	1.58	1	Upgrade
EBIT	-223.64	-208.57	-117.61	-84.78	-65.65	-81.48	Upgrade
Revenue as Reported	-	-	0.89	2.33	18.74	-	Upgrade

Updated Sep 30, 2025. Source: S&P Global Market Intelligence. Standard template. Financial Sources.

SEC Filings: 10-K · 10-Q