Spyre Therapeutics, Inc. (SYRE)
NASDAQ: SYRE · Real-Time Price · USD
98.75
+3.35 (3.51%)
Jul 9, 2026, 4:00 PM EDT - Market closed

Spyre Therapeutics Statistics

Total Valuation

SYRE has a market cap or net worth of $8.58 billion. The enterprise value is $7.83 billion.

Market Cap8.58B
Enterprise Value 7.83B

Important Dates

The next estimated earnings date is Tuesday, August 4, 2026, after market close.

Earnings Date Aug 4, 2026
Ex-Dividend Date n/a

Share Statistics

SYRE has 86.84 million shares outstanding. The number of shares has increased by 29.57% in one year.

Current Share Class 86.84M
Shares Outstanding 86.84M
Shares Change (YoY) +29.57%
Shares Change (QoQ) +4.61%
Owned by Insiders (%) 5.84%
Owned by Institutions (%) 91.74%
Float 80.98M

Valuation Ratios

PE Ratio n/a
Forward PE n/a
PS Ratio n/a
Forward PS n/a
PB Ratio 15.12
P/TBV Ratio 16.65
P/FCF Ratio n/a
P/OCF Ratio n/a
PEG Ratio n/a
Financial Ratio History

Enterprise Valuation

EV / Earnings n/a
EV / Sales n/a
EV / EBITDA n/a
EV / EBIT n/a
EV / FCF n/a

Financial Position

The company has a current ratio of 8.97

Current Ratio 8.97
Quick Ratio 8.80
Debt / Equity n/a
Debt / EBITDA n/a
Debt / FCF n/a
Interest Coverage n/a

Financial Efficiency

Return on equity (ROE) is -31.11% and return on invested capital (ROIC) is -26.19%.

Return on Equity (ROE) -31.11%
Return on Assets (ROA) -22.65%
Return on Invested Capital (ROIC) -26.19%
Return on Capital Employed (ROCE) -35.60%
Weighted Average Cost of Capital (WACC) 20.88%
Revenue Per Employee n/a
Profits Per Employee -$1.33M
Employee Count112
Asset Turnover n/a
Inventory Turnover n/a

Taxes

Income Tax n/a
Effective Tax Rate n/a

Stock Price Statistics

The stock price has increased by +532.61% in the last 52 weeks. The beta is 3.02, so SYRE's price volatility has been higher than the market average.

Beta (5Y) 3.02
52-Week Price Change +532.61%
50-Day Moving Average 79.16
200-Day Moving Average 45.81
Relative Strength Index (RSI) 66.92
Average Volume (20 Days) 1,810,316

Short Selling Information

The latest short interest is 12.62 million, so 14.53% of the outstanding shares have been sold short.

Short Interest 12.62M
Short Previous Month 12.63M
Short % of Shares Out 14.53%
Short % of Float 15.58%
Short Ratio (days to cover) 11.85

Income Statement

Revenue n/a
Gross Profit -171.65M
Operating Income -241.64M
Pretax Income -179.44M
Net Income -148.70M
EBITDA n/a
EBIT -241.64M
Earnings Per Share (EPS) -$2.17
Full Income Statement

Balance Sheet

The company has $741.47 million in cash and n/a in debt, with a net cash position of $741.47 million or $8.54 per share.

Cash & Cash Equivalents 741.47M
Total Debt n/a
Net Cash 741.47M
Net Cash Per Share $8.54
Equity (Book Value) 670.81M
Book Value Per Share 6.53
Working Capital 678.79M
Full Balance Sheet

Cash Flow

Operating Cash Flow -185.63M
Capital Expenditures n/a
Depreciation & Amortization n/a
Net Borrowing n/a
Free Cash Flow -185.63M
FCF Per Share -$2.14
Full Cash Flow Statement

Margins

Gross Margin n/a
Operating Margin n/a
Pretax Margin n/a
Profit Margin n/a
EBITDA Margin n/a
EBIT Margin n/a
FCF Margin n/a

Dividends & Yields

SYRE does not appear to pay any dividends at this time.

Dividend Per Share n/a
Dividend Yield n/a
Dividend Growth (YoY) n/a
Years of Dividend Growth n/a
Payout Ratio n/a
Buyback Yield -29.57%
Shareholder Yield -29.57%
Earnings Yield -1.73%
FCF Yield -2.16%

Analyst Forecast

The average price target for SYRE is $100.47, which is 1.74% higher than the current price. The consensus rating is "Strong Buy".

Price Target $100.47
Price Target Difference 1.74%
Analyst Consensus Strong Buy
Analyst Count 17
Revenue Growth Forecast (3Y) n/a
EPS Growth Forecast (3Y) n/a
Stock Forecasts

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value n/a
Lynch Upside n/a
Graham Number n/a
Graham Upside n/a

Stock Splits

The last stock split was on September 8, 2023. It was a reverse split with a ratio of 1:25.

Last Split Date Sep 8, 2023
Split Type Reverse
Split Ratio 1:25

Scores

Altman Z-Score n/a
Piotroski F-Score 1