Spyre Therapeutics, Inc. (SYRE)

Spyre Therapeutics Statistics

Total Valuation

SYRE has a market cap or net worth of $6.43 billion. The enterprise value is $5.69 billion.

Market Cap	6.43B
Enterprise Value	5.69B

Important Dates

The last earnings date was Tuesday, May 5, 2026, before market open.

Earnings Date	May 5, 2026
Ex-Dividend Date	n/a

Share Statistics

SYRE has 86.84 million shares outstanding. The number of shares has increased by 29.57% in one year.

Current Share Class	86.84M
Shares Outstanding	86.84M
Shares Change (YoY)	+29.57%
Shares Change (QoQ)	+4.61%
Owned by Insiders (%)	5.90%
Owned by Institutions (%)	96.33%
Float	80.93M

Valuation Ratios

PE Ratio	n/a
Forward PE	n/a
PS Ratio	n/a
Forward PS	n/a
PB Ratio	11.34
P/TBV Ratio	12.49
P/FCF Ratio	n/a
P/OCF Ratio	n/a
PEG Ratio	n/a

Enterprise Valuation

EV / Earnings	n/a
EV / Sales	n/a
EV / EBITDA	n/a
EV / EBIT	n/a
EV / FCF	n/a

Financial Position

The company has a current ratio of 8.97

Current Ratio	8.97
Quick Ratio	8.80
Debt / Equity	n/a
Debt / EBITDA	n/a
Debt / FCF	n/a
Interest Coverage	n/a

Financial Efficiency

Return on equity (ROE) is -31.11% and return on invested capital (ROIC) is -26.19%.

Return on Equity (ROE)	-31.11%
Return on Assets (ROA)	-22.65%
Return on Invested Capital (ROIC)	-26.19%
Return on Capital Employed (ROCE)	-35.60%
Weighted Average Cost of Capital (WACC)	21.46%
Revenue Per Employee	n/a
Profits Per Employee	-$1.33M
Employee Count	112
Asset Turnover	n/a
Inventory Turnover	n/a

Taxes

Income Tax	n/a
Effective Tax Rate	n/a

Stock Price Statistics

The stock price has increased by +401.02% in the last 52 weeks. The beta is 3.13, so SYRE's price volatility has been higher than the market average.

Beta (5Y)	3.13
52-Week Price Change	+401.02%
50-Day Moving Average	61.52
200-Day Moving Average	35.45
Relative Strength Index (RSI)	57.91
Average Volume (20 Days)	1,131,889

Short Selling Information

The latest short interest is 12.22 million, so 14.07% of the outstanding shares have been sold short.

Short Interest	12.22M
Short Previous Month	11.67M
Short % of Shares Out	14.07%
Short % of Float	15.10%
Short Ratio (days to cover)	8.89

Income Statement

Revenue	n/a
Gross Profit	-190.44M
Operating Income	-241.64M
Pretax Income	-179.44M
Net Income	-148.70M
EBITDA	n/a
EBIT	-241.64M
Earnings Per Share (EPS)	-$2.17

Balance Sheet

The company has $741.47 million in cash and n/a in debt, with a net cash position of $741.47 million or $8.54 per share.

Cash & Cash Equivalents	741.47M
Total Debt	n/a
Net Cash	741.47M
Net Cash Per Share	$8.54
Equity (Book Value)	670.81M
Book Value Per Share	6.53
Working Capital	678.79M

Cash Flow

Operating Cash Flow	-185.63M
Capital Expenditures	n/a
Depreciation & Amortization	n/a
Net Borrowing	n/a
Free Cash Flow	-185.63M
FCF Per Share	-$2.14

Margins

Gross Margin	n/a
Operating Margin	n/a
Pretax Margin	n/a
Profit Margin	n/a
EBITDA Margin	n/a
EBIT Margin	n/a
FCF Margin	n/a

Dividends & Yields

SYRE does not appear to pay any dividends at this time.

Dividend Per Share	n/a
Dividend Yield	n/a
Dividend Growth (YoY)	n/a
Years of Dividend Growth	n/a
Payout Ratio	n/a
Buyback Yield	-29.57%
Shareholder Yield	-29.57%
Earnings Yield	-2.31%
FCF Yield	-2.89%

Analyst Forecast

The average price target for SYRE is $95.20, which is 28.56% higher than the current price. The consensus rating is "Strong Buy".

Price Target	$95.20
Price Target Difference	28.56%
Analyst Consensus	Strong Buy
Analyst Count	17
Revenue Growth Forecast (5Y)	n/a
EPS Growth Forecast (5Y)	n/a

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value	n/a
Lynch Upside	n/a
Graham Number	n/a
Graham Upside	n/a

Stock Splits

The last stock split was on September 8, 2023. It was a reverse split with a ratio of 1:25.

Last Split Date	Sep 8, 2023
Split Type	Reverse
Split Ratio	1:25

Scores

Altman Z-Score	n/a
Piotroski F-Score	1