Spyre Therapeutics Stock Forecast

Stock Price Forecast

The 12 analysts that cover Spyre Therapeutics stock have a consensus rating of "Strong Buy" and an average price target of $85.08, which forecasts a 16.53% increase in the stock price over the next year. The lowest target is $53 and the highest is $106.

Price Target: $85.08 (+16.53%)

Analyst Consensus: Strong Buy

Target	Low	Average	Median	High
Price	$53	$85.08	$90	$106
Change	-27.41%	+16.53%	+23.27%	+45.19%

Analyst Ratings

The average analyst rating for Spyre Therapeutics stock is "Strong Buy". This means that analysts believe this stock is likely to perform very well in the near future and significantly outperform the market.

Recommendation Trends

Rating	Nov '25	Dec '25	Jan '26	Feb '26	Mar '26	Apr '26
Strong Buy	3	4	4	4	5	7
Buy	2	2	2	3	3	5
Hold	1	0	0	0	0	0
Sell	0	0	0	0	0	0
Strong Sell	0	0	0	0	0	0
Total	6	6	6	7	8	12

Latest Forecasts

Analyst	Firm	Rating	Rating	Action	Price Target	Upside	Date
Debanjana Chatterjee Jones Trading	Jones Trading	Strong Buy Maintains $64 → $95	Strong Buy	Maintains	$64 → $95	+30.12%	Apr 17, 2026
Yanan Zhu Wells Fargo	Wells Fargo	Buy Maintains $50 → $90	Buy	Maintains	$50 → $90	+23.27%	Apr 14, 2026
David Nierengarten Wedbush	Wedbush	Buy Maintains $65 → $80	Buy	Maintains	$65 → $80	+9.57%	Apr 14, 2026
Colleen Kusy Baird	Baird	Buy Maintains $65 → $90	Buy	Maintains	$65 → $90	+23.27%	Apr 14, 2026
Martin Auster Raymond James	Raymond James	Strong Buy Initiates $80	Strong Buy	Initiates	$80	+9.57%	Apr 14, 2026

More Analyst Ratings

Financial Forecast

Revenue This Year

n/a

Revenue Next Year

n/a

EPS This Year

-2.98

from -1.98

EPS Next Year

-3.19

from -2.98

Fiscal Year	FY 2021	FY 2022	FY 2023	FY 2024	FY 2025	FY 2026	FY 2027
Period Ending	Dec 31, 2021	Dec 31, 2022	Dec 31, 2023	Dec 31, 2024	Dec 31, 2025	Dec 31, 2026	Dec 31, 2027
Revenue	18.74M	2.33M	886.00K	-	-	-	-
Revenue Growth	-	-87.57%	-61.96%	-	-	-	-
EPS	-25.02	-24.86	-13.76	-3.18	-1.98	-2.98	-3.19
EPS Growth	-	-	-	-	-	-	-
Forward PE	-	-	-	-	-	-	-
No. Analysts	-	-	-	-	-	16	16

Historical EPS numbers are GAAP, while forecasted numbers may be non-GAAP.

Revenue Forecast

Revenue	2026	2027
High	n/a	n/a
Avg	n/a	n/a
Low	n/a	n/a

Revenue Growth

Revenue Growth	2026	2027
High	-	-
Avg	-	-
Low	-	-

EPS Forecast

EPS	2026	2027
High	-2.11	-1.48
Avg	-2.98	-3.19
Low	-3.91	-4.76

EPS Growth

EPS Growth	2026	2027
High	-	-
Avg	-	-
Low	-	-

Sources: Price targets and analyst ratings provided by Benzinga. Revenue and EPS forecast data provided by Finnhub. The data is sourced from Wall Street analysts. Data disclaimer.