Spyre Therapeutics Stock Forecast

Stock Price Forecast

According to 17 analysts polled by S&P Global, Spyre Therapeutics stock has a consensus rating of "Strong Buy" and an average price target of $95.2. The average 1-year stock price forecast is 29.52% higher than the current stock price, while the lowest is $78 (+6.12%) and the highest is $115 (+56.46%).

Price Target: $95.2 (+29.52%)

Analyst Consensus: Strong Buy

Target	Low	Average	Median	High
Price	$78	$95.2	$95	$115
Change	+6.12%	+29.52%	+29.25%	+56.46%

Analyst Ratings

The average analyst rating for Spyre Therapeutics stock is "Strong Buy". This means that analysts believe this stock is likely to perform very well in the near future and significantly outperform the market.

Recommendation Trends

Rating	Dec '25	Jan '26	Feb '26	Mar '26	Apr '26	May '26
Strong Buy	16	16	16	16	17	17
Buy	0	0	0	0	0	0
Hold	0	0	0	0	0	0
Sell	0	0	0	0	0	0
Strong Sell	0	0	0	0	0	0
Total	16	16	16	16	17	17

Latest Forecasts

Analyst	Firm	Rating	Rating	Action	Price Target	Upside	Date
Debanjana Chatterjee JonesTrading	JonesTrading	Buy Maintains $95	Buy	Maintains	$95	+29.25%	May 18, 2026
Sam Slutsky LifeSci Capital	LifeSci Capital	Buy Maintains $103	Buy	Maintains	$103	+40.14%	May 17, 2026
David Hoang Deutsche Bank	Deutsche Bank	Buy Maintains $86 → $102	Buy	Maintains	$86 → $102	+38.78%	May 12, 2026
Alex Thompson CFA Stifel Nicolaus	Stifel Nicolaus	Buy Maintains $107	Buy	Maintains	$107	+45.58%	May 12, 2026
Unknown Analyst Guggenheim No rating	Guggenheim	Buy Reiterates $115	Buy	Reiterates	$115	+56.46%	May 7, 2026

More Analyst Ratings

Financial Forecast

Revenue This Year

n/a

Revenue Next Year

n/a

EPS This Year

-2.87

from -1.98

EPS Next Year

-3.20

from -2.87

Fiscal Year	FY 2021	FY 2022	FY 2023	FY 2024	FY 2025	FY 2026	FY 2027
Period Ending	Dec 31, 2021	Dec 31, 2022	Dec 31, 2023	Dec 31, 2024	Dec 31, 2025	Dec 31, 2026	Dec 31, 2027
Revenue	18.74M	2.33M	886.00K	-	-	-	-
Revenue Growth	-	-87.57%	-61.96%	-	-	-	-
EPS	-25.02	-24.86	-13.76	-3.18	-1.98	-2.87	-3.20
EPS Growth	-	-	-	-	-	-	-
Forward PE	-	-	-	-	-	-	-
No. Analysts	-	-	-	-	-	17	17

Historical EPS numbers are GAAP, while forecasted numbers may be non-GAAP.

Revenue Forecast

Revenue	2026	2027
High	n/a	n/a
Avg	n/a	n/a
Low	n/a	n/a

Revenue Growth

Revenue Growth	2026	2027
High	-	-
Avg	-	-
Low	-	-

EPS Forecast

EPS	2026	2027
High	-2.11	-1.48
Avg	-2.87	-3.20
Low	-3.26	-4.54

EPS Growth

EPS Growth	2026	2027
High	-	-
Avg	-	-
Low	-	-

Sources: Price targets and consensus ratings provided by S&P Global Market Intelligence. Historical ratings and analyst data provided by TipRanks. Revenue and EPS forecast data provided by Finnhub. The data is sourced from Wall Street analysts. Data sources.