Spyre Therapeutics, Inc. (SYRE)

NASDAQ: SYRE · Real-Time Price · USD

74.05

-0.27 (-0.36%)

At close: May 22, 2026, 4:00 PM EDT

74.05

0.00 (0.00%)

After-hours: May 22, 2026, 4:00 PM EDT

Spyre Therapeutics Income Statement

Financials in millions USD. Fiscal year is January - December.

Millions USD. Fiscal year is Jan - Dec.

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Mar '26 Mar 31, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Selling, General & Admin	51.2	47.91	45.78	39.95	28.53	27.32
Research & Development	190.44	171.65	162.79	89.5	58.58	57.07
Other Operating Expenses	40	10	-	146.64	-	-
Total Operating Expenses	281.64	229.56	208.57	276.09	87.11	84.39
Operating Income	-201.64	-209.56	-208.57	-242.3	-84.78	-65.65
Interest Income	25.39	24.89	21.31	6.15	0.84	0.11
Other Non-Operating Income (Expense)	25.39	24.89	21.31	6.15	0.84	0.11
Total Non-Operating Income (Expense)	50.77	49.77	42.62	12.29	1.67	0.22
Pretax Income	-179.44	-155.22	-207.97	-338.82	-83.95	-65.66
Provision for Income Taxes	-	0.02	-0.05	0.03	0.14	-0.14
Net Income	-179.44	-155.2	-208.02	-338.79	-83.82	-65.8
Net Income to Common	-179.44	-155.2	-208.02	-338.79	-83.82	-65.8
Shares Outstanding (Basic)	86	64	47	7	3	3
Shares Outstanding (Diluted)	86	64	47	7	3	3
Shares Change (YoY)	26.34%	36.21%	581.85%	104.57%	28.20%	23.19%
EPS (Basic)	-2.08	-1.98	-3.18	-13.76	-24.86	-25.02
EPS (Diluted)	-2.08	-1.98	-3.18	-13.76	-24.86	-25.02
Shares Outstanding	93.35	92.7	60.26	36.06	2.61	1.97
Free Cash Flow	-185.63	-169.25	-157.41	-99.91	-80.18	-54.29
Free Cash Flow Per Share	-2.15	-2.64	-3.35	-14.49	-23.78	-20.64
EBITDA	-201.64	-209.56	-208.57	-241.56	-83.21	-64.07
EBIT	-201.64	-209.56	-208.57	-242.3	-84.78	-65.65
Effective Tax Rate	-	-0.01%	0.02%	-0.01%	-0.16%	0.21%

Updated May 5, 2026. Data Source: Fiscal.ai. Standard template. Financial Sources.

SEC Filings: 10-K · 10-Q