Spyre Therapeutics Stock Forecast

Stock Price Forecast

The 8 analysts that cover Spyre Therapeutics stock have a consensus rating of "Strong Buy" and an average price target of $60.13, which forecasts a 27.10% increase in the stock price over the next year. The lowest target is $43 and the highest is $92.

Price Target: $60.13 (+27.10%)

Analyst Consensus: Strong Buy

Target	Low	Average	Median	High
Price	$43	$60.13	$64	$92
Change	-9.11%	+27.10%	+35.28%	+94.46%

Analyst Ratings

The average analyst rating for Spyre Therapeutics stock is "Strong Buy". This means that analysts believe this stock is likely to perform very well in the near future and significantly outperform the market.

Recommendation Trends

Rating	Oct '25	Nov '25	Dec '25	Jan '26	Feb '26	Mar '26
Strong Buy	3	3	4	4	4	5
Buy	2	2	2	2	3	3
Hold	1	1	0	0	0	0
Sell	0	0	0	0	0	0
Strong Sell	0	0	0	0	0	0
Total	6	6	6	6	7	8

Latest Forecasts

Analyst	Firm	Rating	Rating	Action	Price Target	Upside	Date
Alex Thompson Stifel	Stifel	Strong Buy Maintains $70 → $92	Strong Buy	Maintains	$70 → $92	+94.46%	Mar 18, 2026
Julian Harrison BTIG	BTIG	Strong Buy Reiterates $70	Strong Buy	Reiterates	$70	+47.96%	Mar 16, 2026
Yanan Zhu Wells Fargo	Wells Fargo	Buy Maintains $40 → $50	Buy	Maintains	$40 → $50	+5.69%	Feb 20, 2026
Julian Harrison BTIG	BTIG	Strong Buy Reiterates $70	Strong Buy	Reiterates	$70	+47.96%	Feb 20, 2026
Julian Harrison BTIG	BTIG	Strong Buy Reiterates $70	Strong Buy	Reiterates	$70	+47.96%	Jan 16, 2026

More Analyst Ratings

Financial Forecast

Revenue This Year

n/a

Revenue Next Year

n/a

EPS This Year

-2.99

from -1.98

EPS Next Year

-3.22

from -2.99

Fiscal Year	FY 2021	FY 2022	FY 2023	FY 2024	FY 2025	FY 2026	FY 2027
Period Ending	Dec 31, 2021	Dec 31, 2022	Dec 31, 2023	Dec 31, 2024	Dec 31, 2025	Dec 31, 2026	Dec 31, 2027
Revenue	18.74M	2.33M	886.00K	-	-	-	-
Revenue Growth	-	-87.57%	-61.96%	-	-	-	-
EPS	-25.02	-24.86	-13.76	-3.18	-1.98	-2.99	-3.22
EPS Growth	-	-	-	-	-	-	-
Forward PE	-	-	-	-	-	-	-
No. Analysts	-	-	-	-	-	16	15

Historical EPS numbers are GAAP, while forecasted numbers may be non-GAAP.

Revenue Forecast

Revenue	2026	2027
High	n/a	n/a
Avg	n/a	n/a
Low	n/a	n/a

Revenue Growth

Revenue Growth	2026	2027
High	-	-
Avg	-	-
Low	-	-

EPS Forecast

EPS	2026	2027
High	-2.11	-1.48
Avg	-2.99	-3.22
Low	-3.91	-4.76

EPS Growth

EPS Growth	2026	2027
High	-	-
Avg	-	-
Low	-	-

Sources: Price targets and analyst ratings provided by Benzinga. Revenue and EPS forecast data provided by Finnhub. The data is sourced from Wall Street analysts. Data disclaimer.