Spyre Therapeutics, Inc. (SYRE)
NASDAQ: SYRE · Real-Time Price · USD
78.48
+4.96 (6.75%)
At close: Jun 4, 2026, 4:00 PM EDT
78.57
+0.09 (0.11%)
Pre-market: Jun 5, 2026, 7:29 AM EDT
Spyre Therapeutics Stock Forecast
Stock Price Forecast
According to 17 analysts polled by S&P Global, Spyre Therapeutics stock has a consensus rating of "Strong Buy" and an average price target of $96.07. The average 1-year stock price forecast is 22.41% higher than the current stock price, while the lowest is $78 (-0.61%) and the highest is $115 (+46.53%).
Price Target: $96.07 (+22.41%)
Analyst Consensus: Strong Buy
Analyst Ratings
The average analyst rating for Spyre Therapeutics stock is "Strong Buy". This means that analysts believe this stock is likely to perform very well in the near future and significantly outperform the market.
Recommendation Trends
| Rating | Jan '26 | Feb '26 | Mar '26 | Apr '26 | May '26 | Jun '26 |
|---|---|---|---|---|---|---|
| Strong Buy | 16 | 16 | 16 | 17 | 17 | 17 |
| Buy | 0 | 0 | 0 | 0 | 0 | 0 |
| Hold | 0 | 0 | 0 | 0 | 0 | 0 |
| Sell | 0 | 0 | 0 | 0 | 0 | 0 |
| Strong Sell | 0 | 0 | 0 | 0 | 0 | 0 |
| Total | 16 | 16 | 16 | 17 | 17 | 17 |
Latest Forecasts
| Analyst | Firm | Rating | Rating | Action | Price Target | Upside | Date |
|---|---|---|---|---|---|---|---|
| Evercore ISI | Evercore ISI | Buy Maintains n/a | Buy | Maintains | n/a | n/a | Jun 3, 2026 |
| JonesTrading | JonesTrading | Buy Maintains $95 | Buy | Maintains | $95 | +21.05% | May 18, 2026 |
| LifeSci Capital | LifeSci Capital | Buy Maintains $103 | Buy | Maintains | $103 | +31.24% | May 17, 2026 |
| Deutsche Bank | Deutsche Bank | Buy Maintains $86 → $102 | Buy | Maintains | $86 → $102 | +29.97% | May 12, 2026 |
| Stifel Nicolaus | Stifel Nicolaus | Buy Maintains $107 | Buy | Maintains | $107 | +36.34% | May 12, 2026 |
Financial Forecast
Revenue This Year
n/a
Revenue Next Year
n/a
EPS This Year
-3.00
from -1.98
EPS Next Year
-3.26
from -3.00
Revenue Forecast
| Revenue | 2026 | 2027 | 2028 |
|---|---|---|---|
| High | n/a | ||
| Avg | n/a | ||
| Low | n/a |
Revenue Growth
| Revenue Growth | 2027 | 2028 |
|---|---|---|
| High | - | |
| Avg | - | |
| Low | - |
EPS Forecast
| EPS | 2026 | 2027 | 2028 |
|---|---|---|---|
| High | -2.42 | ||
| Avg | -3.00 | ||
| Low | -3.78 |
EPS Growth
| EPS Growth | 2026 | 2027 | 2028 |
|---|---|---|---|
| High | - | ||
| Avg | - | ||
| Low | - |
Sources: Price targets and consensus ratings provided by S&P Global Market Intelligence. Historical ratings and analyst data provided by TipRanks. Financial forecast data provided by S&P Global Market Intelligence. The data is sourced from Wall Street analysts. Data sources.