Spyre Therapeutics, Inc. (SYRE)
NASDAQ: SYRE · Real-Time Price · USD
79.90
-0.20 (-0.25%)
At close: Oct 16, 2026, 4:00 PM EDT
78.90
-1.00 (-1.25%)
After-hours: Oct 16, 2026, 7:59 PM EDT
Spyre Therapeutics Analyst Ratings
Ratings History
| Analyst | Firm | Rating | Rating | Action | Price Target | Upside | Date |
|---|---|---|---|---|---|---|---|
| UBS | UBS | Buy Initiates $120 | Buy | Initiates | $120 | +50.19% | Oct 11, 2026 |
| Wells Fargo | Wells Fargo | Buy Maintains $115 | Buy | Maintains | $115 | +43.93% | Oct 3, 2026 |
| JonesTrading | JonesTrading | Buy Reiterates $121 → $130 | Buy | Reiterates | $121 → $130 | +62.70% | Oct 1, 2026 |
| J.P. Morgan | J.P. Morgan | Buy Initiates $110 | Buy | Initiates | $110 | +37.67% | Oct 1, 2026 |
| Wedbush | Wedbush | Buy Maintains $123 | Buy | Maintains | $123 | +53.94% | Sep 9, 2026 |
| Jefferies | Jefferies | Buy Maintains $98 → $126 | Buy | Maintains | $98 → $126 | +57.70% | Sep 9, 2026 |
| Leerink Partners | Leerink Partners | Buy Reiterates $124 → $128 | Buy | Reiterates | $124 → $128 | +60.20% | Sep 9, 2026 |
| LifeSci Capital | LifeSci Capital | Buy Maintains $116 | Buy | Maintains | $116 | +45.18% | Sep 8, 2026 |
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Analyst Star Rankings
Our analyst star rankings are based on these four factors
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- The percentage of ratings that are profitable.
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- The average percentage return within one year of the rating.
- Rating Count
- The more ratings the analyst has provided, the higher the score.
- Recency
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