Spyre Therapeutics, Inc. (SYRE)
NASDAQ: SYRE · Real-Time Price · USD
85.69
-1.40 (-1.61%)
At close: Sep 25, 2026, 4:00 PM EDT
85.69
0.00 (0.00%)
After-hours: Sep 25, 2026, 7:30 PM EDT

Spyre Therapeutics Analyst Ratings

Ratings History

AnalystFirmRatingRatingActionPrice TargetUpsideDate
Wedbush
Wedbush
Buy
Maintains
$123
BuyMaintains$123+43.54%Sep 9, 2026
Jefferies
Jefferies
Buy
Maintains
$98 → $126
BuyMaintains$98 → $126+47.04%Sep 9, 2026
Leerink Partners
Leerink Partners
Buy
Reiterates
$124 → $128
BuyReiterates$124 → $128+49.38%Sep 9, 2026
LifeSci Capital
LifeSci Capital
Buy
Maintains
$116
BuyMaintains$116+35.37%Sep 8, 2026
Guggenheim
Guggenheim
Buy
Reiterates
$130
BuyReiterates$130+51.71%Aug 27, 2026
JonesTrading
JonesTrading
Buy
Reiterates
$140 → $121
BuyReiterates$140 → $121+41.21%Aug 26, 2026
BTIG
BTIG
Buy
Reiterates
$132 → $121
BuyReiterates$132 → $121+41.21%Aug 26, 2026
Wells Fargo
Wells Fargo
Buy
Maintains
$90 → $115
BuyMaintains$90 → $115+34.20%Aug 26, 2026

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Analyst Star Rankings

Our analyst star rankings are based on these four factors

Success Rate
The percentage of ratings that are profitable.
Average Return
The average percentage return within one year of the rating.
Rating Count
The more ratings the analyst has provided, the higher the score.
Recency
Ratings provided within the past year contribute to a higher score.