Spyre Therapeutics, Inc. (SYRE)
NASDAQ: SYRE · Real-Time Price · USD
103.86
+7.27 (7.53%)
At close: Nov 6, 2026, 4:00 PM EST
103.00
-0.86 (-0.83%)
After-hours: Nov 6, 2026, 7:30 PM EST
Spyre Therapeutics Analyst Ratings
Ratings History
| Analyst | Firm | Rating | Rating | Action | Price Target | Upside | Date |
|---|---|---|---|---|---|---|---|
| Wells Fargo | Wells Fargo | Buy Reiterates $115 | Buy | Reiterates | $115 | +10.73% | Nov 5, 2026 |
| JonesTrading | JonesTrading | Buy Maintains $130 | Buy | Maintains | $130 | +25.17% | Nov 4, 2026 |
| Guggenheim | Guggenheim | Buy Reiterates $130 → $135 | Buy | Reiterates | $130 → $135 | +29.98% | Nov 4, 2026 |
| BTIG | BTIG | Buy Maintains $121 | Buy | Maintains | $121 | +16.50% | Nov 4, 2026 |
| Wedbush | Wedbush | Buy Maintains $123 → $120 | Buy | Maintains | $123 → $120 | +15.54% | Nov 4, 2026 |
| Stifel Nicolaus | Stifel Nicolaus | Buy Reiterates $123 → $131 | Buy | Reiterates | $123 → $131 | +26.13% | Nov 4, 2026 |
| Citi | Citi | Buy Maintains $97 → $119 | Buy | Maintains | $97 → $119 | +14.58% | Oct 20, 2026 |
| UBS | UBS | Buy Initiates $120 | Buy | Initiates | $120 | +15.54% | Oct 11, 2026 |
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Analyst Star Rankings
Our analyst star rankings are based on these four factors
- Success Rate
- The percentage of ratings that are profitable.
- Average Return
- The average percentage return within one year of the rating.
- Rating Count
- The more ratings the analyst has provided, the higher the score.
- Recency
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