Spyre Therapeutics, Inc. (SYRE)

Spyre Therapeutics Statistics

Total Valuation

SYRE has a market cap or net worth of $1.05 billion. The enterprise value is $528.02 million.

Market Cap	1.05B
Enterprise Value	528.02M

Important Dates

The last earnings date was Tuesday, August 5, 2025, after market close.

Earnings Date	Aug 5, 2025
Ex-Dividend Date	n/a

Share Statistics

SYRE has 60.40 million shares outstanding. The number of shares has increased by 122.82% in one year.

Current Share Class	60.40M
Shares Outstanding	60.40M
Shares Change (YoY)	+122.82%
Shares Change (QoQ)	+0.11%
Owned by Insiders (%)	8.72%
Owned by Institutions (%)	93.01%
Float	46.75M

Valuation Ratios

PE Ratio	n/a
Forward PE	n/a
PS Ratio	n/a
Forward PS	n/a
PB Ratio	3.38
P/TBV Ratio	3.52
P/FCF Ratio	n/a
P/OCF Ratio	n/a
PEG Ratio	n/a

Enterprise Valuation

EV / Earnings	n/a
EV / Sales	n/a
EV / EBITDA	n/a
EV / EBIT	n/a
EV / FCF	n/a

Financial Position

The company has a current ratio of 6.49

Current Ratio	6.49
Quick Ratio	6.38
Debt / Equity	n/a
Debt / EBITDA	n/a
Debt / FCF	n/a
Interest Coverage	n/a

Financial Efficiency

Return on equity (ROE) is -49.83% and return on invested capital (ROIC) is -33.45%.

Return on Equity (ROE)	-49.83%
Return on Assets (ROA)	-28.48%
Return on Invested Capital (ROIC)	-33.45%
Return on Capital Employed (ROCE)	-48.74%
Revenue Per Employee	n/a
Profits Per Employee	-$2.49M
Employee Count	65
Asset Turnover	n/a
Inventory Turnover	n/a

Taxes

In the past 12 months, SYRE has paid $4,000 in taxes.

Income Tax	4,000
Effective Tax Rate	n/a

Stock Price Statistics

The stock price has decreased by -34.59% in the last 52 weeks. The beta is 2.83, so SYRE's price volatility has been higher than the market average.

Beta (5Y)	2.83
52-Week Price Change	-34.59%
50-Day Moving Average	16.24
200-Day Moving Average	19.58
Relative Strength Index (RSI)	57.01
Average Volume (20 Days)	518,484

Short Selling Information

The latest short interest is 12.88 million, so 21.32% of the outstanding shares have been sold short.

Short Interest	12.88M
Short Previous Month	13.60M
Short % of Shares Out	21.32%
Short % of Float	27.55%
Short Ratio (days to cover)	22.70

Income Statement

Revenue	n/a
Gross Profit	-176.99M
Operating Income	-222.15M
Pretax Income	-185.95M
Net Income	-161.72M
EBITDA	n/a
EBIT	-222.15M
Earnings Per Share (EPS)	-$2.85

Balance Sheet

The company has $526.58 million in cash and n/a in debt, giving a net cash position of $526.58 million or $8.72 per share.

Cash & Cash Equivalents	526.58M
Total Debt	n/a
Net Cash	526.58M
Net Cash Per Share	$8.72
Equity (Book Value)	455.77M
Book Value Per Share	4.97
Working Capital	455.77M

Cash Flow

Operating Cash Flow	-154.18M
Capital Expenditures	n/a
Free Cash Flow	-154.18M
FCF Per Share	-$2.55

Margins

Gross Margin	n/a
Operating Margin	n/a
Pretax Margin	n/a
Profit Margin	n/a
EBITDA Margin	n/a
EBIT Margin	n/a
FCF Margin	n/a

Dividends & Yields

SYRE does not appear to pay any dividends at this time.

Dividend Per Share	n/a
Dividend Yield	n/a
Dividend Growth (YoY)	n/a
Years of Dividend Growth	n/a
Payout Ratio	n/a
Buyback Yield	-122.82%
Shareholder Yield	-122.82%
Earnings Yield	-15.33%
FCF Yield	-14.62%

Analyst Forecast

The average price target for SYRE is $55.00, which is 216.46% higher than the current price. The consensus rating is "Buy".

Price Target	$55.00
Price Target Difference	216.46%
Analyst Consensus	Buy
Analyst Count	5
Revenue Growth Forecast (5Y)	n/a
EPS Growth Forecast (5Y)	3.61%

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value	n/a
Lynch Upside	n/a
Graham Number	n/a
Graham Upside	n/a

Stock Splits

The last stock split was on September 8, 2023. It was a reverse split with a ratio of 1:25.

Last Split Date	Sep 8, 2023
Split Type	Reverse
Split Ratio	1:25

Scores

Altman Z-Score	n/a
Piotroski F-Score	1