Spyre Therapeutics, Inc. (SYRE)
NASDAQ: SYRE · Real-Time Price · USD
107.82
+3.22 (3.08%)
Aug 18, 2026, 4:00 PM EDT - Market closed

Spyre Therapeutics Statistics

Total Valuation

SYRE has a market cap or net worth of $9.51 billion. The enterprise value is $8.36 billion.

Market Cap9.51B
Enterprise Value 8.36B

Important Dates

The last earnings date was Tuesday, August 4, 2026, after market close.

Earnings Date Aug 4, 2026
Ex-Dividend Date n/a

Share Statistics

SYRE has 88.17 million shares outstanding. The number of shares has increased by 31.80% in one year.

Current Share Class 88.17M
Shares Outstanding 88.17M
Shares Change (YoY) +31.80%
Shares Change (QoQ) +7.87%
Owned by Insiders (%) 5.72%
Owned by Institutions (%) 109.01%
Float 82.15M

Valuation Ratios

PE Ratio n/a
Forward PE n/a
PS Ratio n/a
Forward PS n/a
PB Ratio 9.95
P/TBV Ratio 9.96
P/FCF Ratio n/a
P/OCF Ratio n/a
PEG Ratio n/a
Financial Ratio History

Enterprise Valuation

EV / Earnings n/a
EV / Sales n/a
EV / EBITDA n/a
EV / EBIT n/a
EV / FCF n/a

Financial Position

The company has a current ratio of 18.53

Current Ratio 18.53
Quick Ratio 18.23
Debt / Equity n/a
Debt / EBITDA n/a
Debt / FCF n/a
Interest Coverage n/a

Financial Efficiency

Return on equity (ROE) is -22.98% and return on invested capital (ROIC) is -21.79%.

Return on Equity (ROE) -22.98%
Return on Assets (ROA) -19.81%
Return on Invested Capital (ROIC) -21.79%
Return on Capital Employed (ROCE) -24.45%
Weighted Average Cost of Capital (WACC) 20.89%
Revenue Per Employee n/a
Profits Per Employee -$1.20M
Employee Count125
Asset Turnover n/a
Inventory Turnover n/a

Taxes

Income Tax n/a
Effective Tax Rate n/a

Stock Price Statistics

The stock price has increased by +536.11% in the last 52 weeks. The beta is 3.03, so SYRE's price volatility has been higher than the market average.

Beta (5Y) 3.03
52-Week Price Change +536.11%
50-Day Moving Average 94.96
200-Day Moving Average 57.22
Relative Strength Index (RSI) 61.18
Average Volume (20 Days) 812,256

Short Selling Information

The latest short interest is 12.14 million, so 13.77% of the outstanding shares have been sold short.

Short Interest 12.14M
Short Previous Month 12.51M
Short % of Shares Out 13.77%
Short % of Float 14.78%
Short Ratio (days to cover) 10.58

Income Statement

Revenue n/a
Gross Profit -215.80M
Operating Income -271.34M
Pretax Income -178.92M
Net Income -150.21M
EBITDA n/a
EBIT -271.34M
Earnings Per Share (EPS) -$2.01
Full Income Statement

Balance Sheet

The company has $1.15 billion in cash and no debt, with a net cash position of $1.15 billion or $12.99 per share.

Cash & Cash Equivalents 1.15B
Total Debt n/a
Net Cash 1.15B
Net Cash Per Share $12.99
Equity (Book Value) 1.10B
Book Value Per Share 10.84
Working Capital 1.11B
Full Balance Sheet

Cash Flow

Operating Cash Flow -208.94M
Capital Expenditures n/a
Depreciation & Amortization n/a
Net Borrowing n/a
Free Cash Flow -208.94M
FCF Per Share -$2.37
Full Cash Flow Statement

Margins

Gross Margin n/a
Operating Margin n/a
Pretax Margin n/a
Profit Margin n/a
EBITDA Margin n/a
EBIT Margin n/a
FCF Margin n/a

Dividends & Yields

SYRE does not appear to pay any dividends at this time.

Dividend Per Share n/a
Dividend Yield n/a
Dividend Growth (YoY) n/a
Years of Dividend Growth n/a
Payout Ratio n/a
Buyback Yield -31.80%
Shareholder Yield -31.80%
Earnings Yield -1.58%
FCF Yield -2.20%

Analyst Forecast

The average price target for SYRE is $124.71, which is 15.67% higher than the current price. The consensus rating is "Strong Buy".

Price Target $124.71
Price Target Difference 15.67%
Analyst Consensus Strong Buy
Analyst Count 17
Revenue Growth Forecast (3Y) n/a
EPS Growth Forecast (3Y) n/a
Stock Forecasts

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value n/a
Lynch Upside n/a
Graham Number n/a
Graham Upside n/a

Stock Splits

The last stock split was on September 8, 2023. It was a reverse split with a ratio of 1:25.

Last Split Date Sep 8, 2023
Split Type Reverse
Split Ratio 1:25

Scores

Altman Z-Score n/a
Piotroski F-Score 1