Spyre Therapeutics, Inc. (SYRE)

Spyre Therapeutics Statistics

Total Valuation

SYRE has a market cap or net worth of $3.38 billion. The enterprise value is $2.62 billion.

Market Cap	3.38B
Enterprise Value	2.62B

Important Dates

The last earnings date was Thursday, February 19, 2026, after market close.

Earnings Date	Feb 19, 2026
Ex-Dividend Date	n/a

Share Statistics

SYRE has 78.54 million shares outstanding. The number of shares has increased by 36.21% in one year.

Current Share Class	78.54M
Shares Outstanding	78.54M
Shares Change (YoY)	+36.21%
Shares Change (QoQ)	+24.29%
Owned by Insiders (%)	6.68%
Owned by Institutions (%)	93.43%
Float	64.36M

Valuation Ratios

PE Ratio	n/a
Forward PE	n/a
PS Ratio	n/a
Forward PS	n/a
PB Ratio	6.01
P/TBV Ratio	6.04
P/FCF Ratio	n/a
P/OCF Ratio	n/a
PEG Ratio	n/a

Enterprise Valuation

EV / Earnings	n/a
EV / Sales	n/a
EV / EBITDA	n/a
EV / EBIT	n/a
EV / FCF	n/a

Financial Position

The company has a current ratio of 13.25

Current Ratio	13.25
Quick Ratio	12.94
Debt / Equity	n/a
Debt / EBITDA	n/a
Debt / FCF	n/a
Interest Coverage	n/a

Financial Efficiency

Return on equity (ROE) is -25.17% and return on invested capital (ROIC) is -22.26%.

Return on Equity (ROE)	-25.17%
Return on Assets (ROA)	-19.80%
Return on Invested Capital (ROIC)	-22.26%
Return on Capital Employed (ROCE)	-30.53%
Weighted Average Cost of Capital (WACC)	21.64%
Revenue Per Employee	n/a
Profits Per Employee	-$1.33M
Employee Count	95
Asset Turnover	n/a
Inventory Turnover	n/a

Taxes

Income Tax	-15,000
Effective Tax Rate	n/a

Stock Price Statistics

The stock price has increased by +126.37% in the last 52 weeks. The beta is 3.16, so SYRE's price volatility has been higher than the market average.

Beta (5Y)	3.16
52-Week Price Change	+126.37%
50-Day Moving Average	34.37
200-Day Moving Average	22.96
Relative Strength Index (RSI)	71.18
Average Volume (20 Days)	743,152

Short Selling Information

The latest short interest is 9.86 million, so 12.56% of the outstanding shares have been sold short.

Short Interest	9.86M
Short Previous Month	9.98M
Short % of Shares Out	12.56%
Short % of Float	15.32%
Short Ratio (days to cover)	15.96

Income Statement

Revenue	n/a
Gross Profit	-171.65M
Operating Income	-219.56M
Pretax Income	-155.22M
Net Income	-126.54M
EBITDA	n/a
EBIT	-219.56M
Earnings Per Share (EPS)	-$1.98

Balance Sheet

The company has $756.53 million in cash and n/a in debt, with a net cash position of $756.53 million or $9.63 per share.

Cash & Cash Equivalents	756.53M
Total Debt	n/a
Net Cash	756.53M
Net Cash Per Share	$9.63
Equity (Book Value)	715.24M
Book Value Per Share	7.15
Working Capital	719.10M

Cash Flow

Operating Cash Flow	-169.25M
Capital Expenditures	n/a
Free Cash Flow	-169.25M
FCF Per Share	-$2.15

Margins

Gross Margin	n/a
Operating Margin	n/a
Pretax Margin	n/a
Profit Margin	n/a
EBITDA Margin	n/a
EBIT Margin	n/a
FCF Margin	n/a

Dividends & Yields

SYRE does not appear to pay any dividends at this time.

Dividend Per Share	n/a
Dividend Yield	n/a
Dividend Growth (YoY)	n/a
Years of Dividend Growth	n/a
Payout Ratio	n/a
Buyback Yield	-36.21%
Shareholder Yield	-36.21%
Earnings Yield	-3.75%
FCF Yield	-5.01%

Analyst Forecast

The average price target for SYRE is $55.57, which is 29.20% higher than the current price. The consensus rating is "Strong Buy".

Price Target	$55.57
Price Target Difference	29.20%
Analyst Consensus	Strong Buy
Analyst Count	7
Revenue Growth Forecast (5Y)	n/a
EPS Growth Forecast (5Y)	14.36%

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value	n/a
Lynch Upside	n/a
Graham Number	n/a
Graham Upside	n/a

Stock Splits

The last stock split was on September 8, 2023. It was a reverse split with a ratio of 1:25.

Last Split Date	Sep 8, 2023
Split Type	Reverse
Split Ratio	1:25

Scores

Altman Z-Score	n/a
Piotroski F-Score	1