Upstream Bio, Inc. (UPB)

Upstream Bio Revenue

Upstream Bio had revenue of $395.00K in the quarter ending September 30, 2026, a decrease of -42.17%. This brings the company's total for the last twelve months to $2.87M, up 2.54% year-over-year. In the year 2025, Upstream Bio had annual revenue of $2.85M with 20.42% growth. That makes Upstream Bio the 41,604th largest company in the world by revenue and 5,610th in the United States.

• Revenue (ttm): $2.87M
• Revenue Growth: +2.54%
• P/S Ratio: 53.09
• Revenue / Employee: $38,267
• Employees: 75
• Market Cap: 152.38M

Revenue Chart

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Revenue History

Fiscal Year End	Revenue	Change	Growth
Dec 31, 2025	2.85M	484.00K	20.42%
Dec 31, 2024	2.37M	-10.00K	-0.42%
Dec 31, 2023	2.38M	1.17M	96.37%
Dec 31, 2022	1.21M	-	-

Data Source: S&P Global Market Intelligence Last updated: Nov 10, 2026

Revenue data is provided by S&P Global Market Intelligence and updates within hours after each earnings release, which is every three months for this company.

Update frequency:

Quarterly

Last checked:

Nov 15, 2026

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