SPDR S&P BIOTECH ETF (XBI)

NYSEARCA: XBI · Real-Time Price · USD
83.68
+0.41 (0.49%)
At close: Jun 26, 2025, 4:00 PM
83.57
-0.11 (-0.13%)
After-hours: Jun 26, 2025, 8:00 PM EDT
0.49%
Assets $4.69B
Expense Ratio 0.35%
PE Ratio n/a
Shares Out 57.00M
Dividend (ttm) $0.03
Dividend Yield 0.04%
Ex-Dividend Date Jun 23, 2025
Payout Ratio n/a
1-Year Return -10.74%
Volume 9,313,995
Open 83.46
Previous Close 83.27
Day's Range 82.81 - 83.92
52-Week Low 66.66
52-Week High 105.47
Beta 0.85
Holdings 130
Inception Date Jan 31, 2006

About XBI

Fund Home Page

The SPDR S&P BIOTECH ETF (XBI) is an exchange-traded fund that is based on the S&P Biotechnology Select Industry index. The fund tracks an equal-weighted index of US biotechnology stocks. XBI was launched on Jan 31, 2006 and is issued by State Street.

Asset Class Equity
Category Health
Region North America
Stock Exchange NYSEARCA
Ticker Symbol XBI
ETF Provider State Street
Index Tracked S&P Biotechnology Select Industry

Top 10 Holdings

24.69% of assets
Name Symbol Weight
Alnylam Pharmaceuticals, Inc. ALNY 2.61%
Insmed Incorporated INSM 2.59%
Exelixis, Inc. EXEL 2.55%
United Therapeutics Corporation UTHR 2.51%
Neurocrine Biosciences, Inc. NBIX 2.49%
Regeneron Pharmaceuticals, Inc. REGN 2.43%
Vertex Pharmaceuticals Incorporated VRTX 2.39%
Natera, Inc. NTRA 2.39%
Incyte Corporation INCY 2.38%
Halozyme Therapeutics, Inc. HALO 2.35%
View More Holdings

Dividends

Ex-Dividend Amount Pay Date
Jun 23, 2025 $0.0073 Jun 25, 2025
Mar 24, 2025 $0.00525 Mar 26, 2025
Dec 23, 2024 $0.00269 Dec 26, 2024
Sep 23, 2024 $0.01523 Sep 25, 2024
Jun 24, 2024 $0.11478 Jun 26, 2024
Dec 18, 2023 $0.01388 Dec 21, 2023
Full Dividend History

News

Pharma companies need to beef up M&A right now, says Mizuho's Jared Holz

Jared Holxz, Mizuho, joins 'Fast Money' to talk competition in the obesity drug space.

3 days ago - CNBC Television

Home builders lose confidence, resort to price cuts as buyers steer clear of housing market

Builders' confidence in the housing market sank in June, the National Association of Home Builders said.

Other symbols: ITB
9 days ago - Market Watch

Healthcare Sector Checkup As U.S. Looks To Change Regulations

Outlook for pharma sector as Trump pushes for regulatory changes. The impact of tariffs on drugmakers.

27 days ago - Seeking Alpha

Trump is right about drug prices. He's just going about it all wrong.

The stock market doesn't believe the president about prescription drugs.

Other symbols: IBBXLV
6 weeks ago - Market Watch

Trump Declares War On Pharma Drug Pricing, But The Stocks Aren't Tanking - Yet

President Trump has announced today he plans to reduce U.S. drug prices by 30-80% via an Executive Order, targeting Big Pharma's high costs and profits. U.S. drug prices are significantly higher (up t...

6 weeks ago - Seeking Alpha

StemPoint's Michelle Ross breaks down navigating the pharmaceutical sector volatility

Michelle Ross, StemPoint Capital CIO, joins 'Closing Bell' to discuss health care's weak week and how to navigate pharma volatility.

Other symbols: XLV
6 weeks ago - CNBC Television

New vaccine chief rocks pharmaceutical stocks

CNBC's Angelica Peebles joins 'Squawk on the Street' to discuss how the biotech and pharma industry is reacting to a new FDA chief of vaccines appointed by President Trump.

7 weeks ago - CNBC Television

We're in a pharma stock pickers market, says Kessef's Len Yaffe

Len Yaffe, Kessef Capital Management, joins 'Fast Money' to talk opportunities in the pharma stock space.

2 months ago - CNBC Television

Sell into strength in pharma, says Mizuho's Jared Holz

Jared Holz, Mizuho, joins 'Fast Money' to talk a rebound in biotech stocks and what new tariffs mean for the pharmaceuticals space.

Other symbols: IBB
2 months ago - CNBC Television

How to Play the Biotech Meltdown in the Age of RFK Jr. and Tariffs

Political pressure and persistently high interest rates have some wondering if the industry's model is broken.

Other symbols: IBB
2 months ago - WSJ

BMO's Siegerman talks the impact of tariffs on pharmaceutical stocks

Evan Seigerman, BMO, joins 'Fast Money' to talk the impact of tariffs on pharma space.

2 months ago - CNBC Television

Vaccine stocks fall following FDA resignation

Dr. Kavita Patel joins 'Fast Money' to talk the impact of FDA and HHS changes on vaccines, public health policy, and more.

3 months ago - CNBC Television

Drug stocks sink as FDA's top vaccine official is ousted in Trump overhaul

Shares of U.S. drugmakers fell on Monday after reports that the Food and Drug Administration's top vaccine official was forced to resign, the most high-profile exit at the regulator as the Trump admin...

Other symbols: BNTXNVAXSLDBSRPTTSHA
3 months ago - New York Post

Stifel's Paul Matteis says look for biotech names not dependent on the FDA amid sector uncertainty

Paul Matteis, Stifel head of biotech research, joins 'The Exchange' to discuss the biotech trade under a new FDA amid the top vaccine official resigning.

Other symbols: ALNYRYTMVRTXXENE
3 months ago - CNBC Television

Single stock picking is the only way to make money in biotech, says Mizuho's Jared Holz

Jared Holz, Mizuho health care equity strategist, joins 'Power Lunch' to discuss investing in biotech and the oversaturation in the sector.

4 months ago - CNBC Television

Trade Tracker: Joe Terranova sells the XBI, buys Amgen

Joe Terranova, Senior Managing Director for Virtus Investment Partners, joins CNBC's "Halftime Report" to detail his latest portfolio moves.

Other symbols: AMGN
4 months ago - CNBC Television

Invest In A New Biotech Bull Market With XBI And IBB

Biotech stocks are oversold. This near-term bottom might be the start of a long-term bull run. IBB and XBI offer different advantages. IBB can benefit from the flight to safety trade. XBI provides mor...

Other symbols: IBB
4 months ago - Seeking Alpha

Seeking Stocks With Vitality In The Volatile Healthcare Sector

Investors cooled to the healthcare sector in 2024, which dramatically trailed global and US equity markets for the year. any investors are now asking: how will the policy changes under a new US admini...

4 months ago - Seeking Alpha

Shareholder Group Led by Founder Mina Sooch Nominates Majority Slate of Director Candidates to the Board of Opus Genetics, Inc.

Current Board's Strategic, Management, and Capital Allocation Failures Have Driven an 80% Stock Decline Over Last 22 Months

Other symbols: IRD
4 months ago - GlobeNewsWire

XBI: Diverse Holding Amid Strong Catalysts, Buy

SPDR® S&P Biotech ETF is a strong investment due to rising demand for biotech solutions addressing chronic diseases and its diverse, equal-weighted portfolio. XBI's equal-weighting strategy reduces co...

5 months ago - Seeking Alpha

3 Biotech Stocks With Notable Insider Buying

Small biotech stocks have struggled recently, with the SPDR® S&P Biotech ETF down over 15% in the past ten weeks. The pullback has presented significantly lower entry points on myriad small and mid-ca...

Other symbols: AUPHAZNCOGTJAZZONCZYME
5 months ago - Seeking Alpha

Top 5 Cancer Pharma Stocks With Strong Risk/Reward In 2025

This article will provide an in-depth analysis of drugs being developed to combat cancer. Big Pharma is keenly interested in the global cancer therapeutics market, which is expected to exceed $400 bil...

5 months ago - Seeking Alpha

3 Oversold Biotech Names

High beta market sectors, including small caps and biotech, sold off significantly last week as the 10-Year Treasury yield surpassed 4.75%. The JP Morgan Healthcare event in San Francisco that opens t...

Other symbols: AVDLFOLDJAZZVKTX
5 months ago - Seeking Alpha

Healthcare has 'been so bad, maybe it's gonna be good' in 2025, says Mizuho's Jared Holz

Jared Holz, Mizuho Securities America healthcare sector strategist, joins CNBC's 'Squawk on the Street' to discuss outlooks on the healthcare sector in the new year

Other symbols: ABTBMYHOLXLLYNVOUNHXLV
6 months ago - CNBC Television

Healthcare Stocks: 2025 Outlook

I forecast healthcare stocks, especially biopharmaceuticals, to outperform the general averages due to four key investment themes. US healthcare expenditures are expected to grow at an annualized rate...

Other symbols: XLV
6 months ago - Seeking Alpha