Spyre Therapeutics, Inc. (SYRE)

NASDAQ: SYRE · Real-Time Price · USD

103.86

+7.27 (7.53%)

At close: Nov 6, 2026, 4:00 PM EST

103.00

-0.86 (-0.83%)

After-hours: Nov 6, 2026, 7:30 PM EST

Spyre Therapeutics Income Statement

Financials in millions USD. Fiscal year is January - December.

Millions USD. Fiscal year is Jan - Dec.

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Sep '26 Sep 30, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Revenue	-	-	-	0.89	2.33	18.74
Revenue Growth	-	-	-	-61.96%	-87.57%	-
Cost of Revenue	259.72	171.65	162.79	84.05	58.58	57.07
Gross Profit	-259.72	-171.65	-162.79	-83.16	-56.25	-38.33
Selling, General & Admin	60.45	47.91	45.78	34.45	28.53	27.32
Operating Expenses	60.45	47.91	45.78	34.45	28.53	27.32
Operating Income	-320.17	-219.56	-208.57	-117.61	-84.78	-65.65
Interest & Investment Income	34.81	24.89	21.31	6.15	0.84	0.11
Other Non Operating Income (Expenses)	-48.5	29.46	-20.71	-102.66	-0.01	-0.12
EBT Excluding Unusual Items	-333.86	-165.22	-207.97	-214.13	-83.95	-65.66
Merger & Restructuring Charges	-	-	-	-10.95	-	-
Gain (Loss) on Sale of Assets	70	10	-	16.45	-	-
Pretax Income	-263.86	-155.22	-207.97	-338.82	-83.95	-65.66
Income Tax Expense	-	-0.02	0.05	-0.03	-0.14	0.14
Net Income	-263.86	-155.2	-208.02	-338.79	-83.82	-65.8
Preferred Dividends & Other Adjustments	-39.85	-28.66	-58.46	-243.91	-	-
Net Income to Common	-224.01	-126.54	-149.56	-94.88	-83.82	-65.8
Net Income Growth	-	-	-	-	-	-
Shares Outstanding (Basic)	82	64	47	7	3	3
Shares Outstanding (Diluted)	82	64	47	7	3	3
Shares Change	38.78%	36.21%	581.85%	104.59%	28.19%	23.18%
EPS (Basic)	-2.73	-1.98	-3.18	-13.76	-24.86	-25.02
EPS (Diluted)	-2.73	-1.98	-3.18	-13.76	-24.86	-25.02
EPS Growth	-	-	-	-	-	-

Additional Metrics

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Sep '26 Sep 30, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Free Cash Flow	-249.32	-169.25	-157.41	-99.91	-80.18	-54.29
Free Cash Flow Per Share	-3.04	-2.64	-3.35	-14.49	-23.78	-20.64
Gross Margin	-	-	-	-	-	-204.55%
Operating Margin	-	-	-	-13274.49%	-3640.23%	-350.33%
Profit Margin	-	-	-	-10709.14%	-3598.76%	-351.14%
Free Cash Flow Margin	-	-	-	-11276.52%	-3442.76%	-289.71%
EBITDA	-	-	-207.82	-116.87	-83.21	-64.07
D&A For EBITDA	-	-	0.74	0.74	1.57	1.58
EBIT	-320.17	-219.56	-208.57	-117.61	-84.78	-65.65
Revenue as Reported	-	-	-	0.89	2.33	18.74

SEC Filings: 10-K · 10-Q