Spyre Therapeutics, Inc. (SYRE)

NASDAQ: SYRE · Real-Time Price · USD

43.21

+5.40 (14.28%)

At close: Feb 20, 2026, 4:00 PM EST

43.34

+0.13 (0.30%)

After-hours: Feb 20, 2026, 7:40 PM EST

Spyre Therapeutics Balance Sheet

Financials in millions USD. Fiscal year is January - December.

Millions USD. Fiscal year is Jan - Dec.

Fiscal Year	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Cash & Equivalents	85.72	89.42	188.89	34.86	15.14
Short-Term Investments	670.81	513.67	150.38	20.85	77.99
Cash & Short-Term Investments	756.53	603.09	339.28	55.71	93.13
Cash Growth	25.44%	77.76%	509.00%	-40.18%	-36.33%
Other Receivables	3	-	-	0.38	0.82
Receivables	3	-	-	0.38	0.82
Prepaid Expenses	18.25	5.39	2.25	6.17	4.95
Total Current Assets	777.78	608.47	341.53	62.26	98.89
Property, Plant & Equipment	-	-	-	7.25	9.15
Other Long-Term Assets	-	0.01	0.33	1.64	1.88
Total Assets	777.78	608.48	341.86	71.14	109.93
Accounts Payable	8.9	0.67	0.9	0.68	3.32
Accrued Expenses	26.77	27.31	29.2	12.82	13.25
Current Portion of Leases	-	-	-	0.64	0.85
Current Unearned Revenue	-	-	-	0.52	2.36
Other Current Liabilities	23.01	26.08	1.88	-	0.37
Total Current Liabilities	58.69	54.06	31.98	14.66	20.14
Long-Term Leases	-	-	-	4	4.62
Long-Term Unearned Revenue	-	-	-	2.18	1.22
Other Long-Term Liabilities	3.86	36.62	125.87	-	-
Total Liabilities	62.55	90.68	157.84	20.84	25.99
Common Stock	0.02	0.01	0.01	0.01	0.01
Additional Paid-In Capital	1,686	1,334	763.19	475.97	425.77
Retained Earnings	-1,128	-972.43	-764.41	-425.62	-341.81
Comprehensive Income & Other	0.87	0.18	0.3	-0.05	-0.02
Total Common Equity	559.42	361.98	-0.91	50.31	83.94
Shareholders' Equity	715.24	517.8	184.02	50.31	83.94
Total Liabilities & Equity	777.78	608.48	341.86	71.14	109.93
Total Debt	-	-	-	4.65	5.48
Net Cash (Debt)	756.53	603.09	339.28	51.07	87.65
Net Cash Growth	25.44%	77.76%	564.39%	-41.74%	-37.73%
Net Cash Per Share	11.81	12.82	49.19	15.15	33.33
Filing Date Shares Outstanding	78.54	60.28	36.15	2.62	1.97
Total Common Shares Outstanding	78.19	60.26	36.06	2.61	1.97
Working Capital	719.1	554.41	309.55	47.6	78.75
Book Value Per Share	7.15	6.01	-0.03	19.24	42.52
Tangible Book Value	559.42	361.98	-0.91	50.31	83.94
Tangible Book Value Per Share	7.15	6.01	-0.03	19.24	42.52
Machinery	-	-	-	2.85	2.82
Leasehold Improvements	-	-	-	4.39	4.39

Updated Dec 31, 2025. Source: S&P Global Market Intelligence. Standard template. Financial Sources.

SEC Filings: 10-K · 10-Q