Upstream Bio, Inc. (UPB)

Upstream Bio Balance Sheet

Financials in millions USD. Fiscal year is January - December.

Fiscal Year	TTM	FY 2024	FY 2023	FY 2022
Period Ending	Sep 30, 2025	Dec 31, 2024	Dec 31, 2023	Dec 31, 2022
Cash & Equivalents	72.16	325.89	25.83	17.05
Short-Term Investments	300.26	144.56	83.98	-
Cash & Short-Term Investments	372.43	470.45	109.81	17.05
Cash Growth	68.78%	328.42%	544.01%	-
Accounts Receivable	0.68	0.61	0.1	0.41
Other Current Assets	15.91	8.1	7.09	0.84
Total Current Assets	389.02	479.16	117	18.31
Net Property, Plant & Equipment	1.98	2.37	0.2	0.16
Other Long-Term Assets	0.19	0.19	-	0.01
Total Assets	391.2	481.72	117.2	18.48
Accounts Payable	3.95	4.04	1.99	0.71
Accrued Expenses	7.24	5.99	4.48	4.06
Current Portion of Leases	0.72	0.7	0.05	0.09
Total Current Liabilities	11.91	10.74	6.52	4.86
Long-Term Leases	0.7	1.13	2.87	0.01
Other Long-Term Liabilities	-	-	-	6.95
Total Long-Term Liabilities	0.7	1.13	2.87	6.95
Total Liabilities	12.61	11.87	9.39	11.81
Common Stock	0.06	0.05	0	0
Additional Paid-in Capital	669.8	660.6	4.82	1.28
Accumulated Other Comprehensive Income	0.49	-0.03	0.02	-
Retained Earnings	-291.76	-190.78	-127.97	-107.44
Total Common Shareholders' Equity	378.58	469.85	-123.13	-106.16
Shareholders' Equity	378.58	469.85	230.94	112.82
Total Liabilities & Equity	391.2	481.72	117.2	18.48
Total Debt	1.42	1.83	2.92	0.09
Net Cash (Debt)	371.01	468.62	106.89	16.96
Net Cash Growth	-20.83%	338.41%	530.37%	-
Net Cash Per Share	7.17	34.25	36.19	5.77
Book Value	378.58	469.85	-123.13	-106.16
Book Value Per Share	7.31	34.34	-41.68	-36.14
Tangible Book Value	378.58	469.85	-123.13	-106.16
Tangible Book Value Per Share	7.31	34.34	-41.68	-36.14

Updated Nov 5, 2025. Data Source: Fiscal.ai. Standard template. Financial Sources.

SEC Filings: 10-K · 10-Q