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Upstream Bio, Inc. (UPB)
NASDAQ: UPB · Real-Time Price · USD
2.770
+0.030 (1.09%)
Oct 26, 2026, 3:32 PM EDT - Market open

Upstream Bio Ratios and Metrics

Millions USD. Fiscal year is Jan - Dec.

Total Valuation

Fiscal Year
CurrentFY 2025FY 2024FY 2023FY 2022
Period Ending
Oct '26 Dec '25 Dec '24 Dec '23 Dec '22
Market Capitalization
1521,467881--
Market Cap Growth
-87.29%66.51%---
Enterprise Value
-1091,0961,043--
Last Close Price
2.7427.1516.44--

Price Ratios

Fiscal Year
CurrentFY 2025FY 2024FY 2023FY 2022
Period Ending
Oct '26 Dec '25 Dec '24 Dec '23 Dec '22
PS Ratio
50.99514.07371.78--
PB Ratio
0.554.321.88--
P/TBV Ratio
0.594.321.88--

EV Ratios

Fiscal Year
CurrentFY 2025FY 2024FY 2023FY 2022
Period Ending
Oct '26 Dec '25 Dec '24 Dec '23 Dec '22
EV/Sales Ratio
-384.07440.20--

Financial Efficiency

Fiscal Year
CurrentFY 2025FY 2024FY 2023FY 2022
Period Ending
Oct '26 Dec '25 Dec '24 Dec '23 Dec '22
Debt / Equity Ratio
0.000.000.0000.01
Net Debt / Equity Ratio
-0.96-1.00-1.00-1.02-2.54
Net Debt / EBITDA Ratio
1.532.126.032.740.71
Net Debt / FCF Ratio
1.912.557.852.880.89
Asset Turnover
0.010.010.010.04-
Quick Ratio
26.3825.5643.9316.893.60
Current Ratio
27.9926.1544.6317.963.77
Return on Equity (ROE)
-46.05%-35.43%-21.75%-35.88%-
Return on Assets (ROA)
-30.28%-23.99%-16.23%-36.96%-
Return on Capital Employed (ROCE)
-62.70%-47.10%-16.50%-36.20%-175.50%

Yields

Fiscal Year
CurrentFY 2025FY 2024FY 2023FY 2022
Period Ending
Oct '26 Dec '25 Dec '24 Dec '23 Dec '22
Earnings Yield
-104.18%-9.78%-7.13%--
FCF Yield
-84.74%-9.10%-6.77%--
Buyback Yield / Dilution
-38.95%-293.59%-363.22%-5.49%-
SEC Filings: 10-K · 10-Q