Upstream Bio Ratios and Metrics

Market cap in millions USD. Fiscal year is January - December.

Millions USD. Fiscal year is Jan - Dec.

Fiscal Year	Current	FY 2025	FY 2024	FY 2023	FY 2022
Period Ending	May '26 May 26, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022
Market Cap	447	1,473	881	-	-
Market Cap Growth	-6.05%	67.10%	-	-	-
Enterprise Value	153.32	1,132	411.92	0	0
Last Close Price	8.21	27.15	16.44	-	-
PS Ratio	134.49	515.96	371.83	-	-
PB Ratio	1.47	4.33	1.88	-	-
P/TBV Ratio	1.46	4.30	0.48	-	-
EV/Sales Ratio	46.15	396.49	173.81	-	-
Debt / Equity Ratio	0.00	0.00	0.00	0.01	0.00
Net Debt / Equity Ratio	-0.96	-1.00	-1.00	0.87	0.16
Net Debt / EBITDA Ratio	1.71	2.12	6.03	2.67	0.71
Net Debt / FCF Ratio	2.10	2.55	7.85	2.81	0.89
Asset Turnover	0.01	0.01	0.01	0.04	0.07
Quick Ratio	21.63	25.44	43.87	16.87	3.60
Current Ratio	23.14	26.15	44.63	17.96	3.77
Return on Equity (ROE)	-48.70%	-35.43%	-17.92%	-11.95%	-21.16%
Return on Assets (ROA)	-51.19%	-38.39%	-25.97%	-59.13%	-129.39%
Return on Invested Capital (ROIC)	-3418.41%	-41869.70%	-7223.78%	3309.74%	715.41%
Return on Capital Employed (ROCE)	-53.35%	-39.53%	-26.74%	-64.54%	-175.52%
Buyback Yield / Dilution	-105.15%	-293.59%	-363.22%	-0.56%	-
Total Shareholder Return	-105.15%	-293.59%	-363.22%	-0.56%	-

Updated May 13, 2026. Data Source: Fiscal.ai. Standard template. Financial Sources.

SEC Filings: 10-K · 10-Q