Upstream Bio, Inc. (UPB)

Upstream Bio Balance Sheet

Financials in millions USD. Fiscal year is January - December.

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022
Period Ending	Mar 31, 2026	Dec 31, 2025	Dec 31, 2024	Dec 31, 2023	Dec 31, 2022
Cash & Equivalents	96.72	101.58	325.89	25.83	17.05
Short-Term Investments	197.86	239.93	144.56	83.98	-
Cash & Short-Term Investments	294.58	341.51	470.45	109.81	17.05
Cash Growth	-31.71%	-27.41%	328.42%	544.01%	-
Accounts Receivable	1.03	0.67	0.61	0.1	0.41
Other Current Assets	20.67	9.62	8.1	7.09	0.84
Total Current Assets	316.28	351.8	479.16	117	18.31
Net Property, Plant & Equipment	1.58	1.78	2.37	0.2	0.16
Other Long-Term Assets	0.19	0.19	0.19	-	0.01
Total Assets	318.05	353.77	481.72	117.2	18.48
Accounts Payable	1.71	2.73	4.04	1.99	0.71
Accrued Expenses	11.24	10.01	5.99	4.48	4.06
Current Portion of Leases	0.72	0.72	0.7	0.05	0.09
Total Current Liabilities	13.67	13.45	10.74	6.52	4.86
Long-Term Leases	0.39	0.55	1.13	2.87	0.01
Other Long-Term Liabilities	-	-	-	-	6.95
Total Long-Term Liabilities	0.39	0.55	1.13	2.87	6.95
Total Liabilities	14.06	14	11.87	9.39	11.81
Common Stock	0.05	0.05	0.05	0	0
Additional Paid-in Capital	678.66	673.41	660.6	4.82	1.28
Accumulated Other Comprehensive Income	0.1	0.53	-0.03	0.02	-
Retained Earnings	-374.81	-334.22	-190.78	-127.97	-107.44
Total Common Shareholders' Equity	304	339.77	469.85	-123.13	-106.16
Shareholders' Equity	304	339.77	469.85	230.94	112.82
Total Liabilities & Equity	318.05	353.77	481.72	117.2	18.48
Total Debt	1.11	1.27	1.83	2.92	0.09
Net Cash (Debt)	293.47	340.24	468.62	106.89	16.96
Net Cash Growth	-13.75%	-27.40%	338.41%	530.37%	-
Net Cash Per Share	5.43	6.32	34.25	36.19	5.77
Book Value	304	339.77	469.85	-123.13	-106.16
Book Value Per Share	5.63	6.31	34.34	-41.68	-36.14
Tangible Book Value	304	339.77	469.85	-123.13	-106.16
Tangible Book Value Per Share	5.63	6.31	34.34	-41.68	-36.14

Updated May 13, 2026. Data Source: Fiscal.ai. Standard template. Financial Sources.

SEC Filings: 10-K · 10-Q