Upstream Bio, Inc. (UPB)

NASDAQ: UPB · Real-Time Price · USD

5.96

-0.23 (-3.72%)

At close: Sep 9, 2026, 4:00 PM EDT

5.88

-0.08 (-1.34%)

After-hours: Sep 9, 2026, 5:15 PM EDT

Upstream Bio Balance Sheet

Financials in millions USD. Fiscal year is January - December.

Millions USD. Fiscal year is Jan - Dec.

Assets

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022
Period Ending	Jun '26 Jun 30, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022
Cash & Equivalents	79.4	101.58	325.89	25.83	17.05
Short-Term Investments	181.91	239.93	144.56	83.98	-
Cash & Short-Term Investments	261.31	341.51	470.45	109.81	17.05
Cash Growth	-33.61%	-27.41%	328.42%	544.01%	-
Accounts Receivable	0.77	0.67	0.61	0.1	0.41
Other Receivables	1.38	1.65	0.57	0.14	-
Receivables	2.15	2.32	1.18	0.24	0.41
Prepaid Expenses	0.3	0.88	0.85	0.02	0.09
Other Current Assets	15.85	7.09	6.68	6.93	0.75
Total Current Assets	279.6	351.8	479.16	117	18.31
Property, Plant & Equipment	1.38	1.78	2.37	0.2	0.16
Other Long-Term Assets	0.19	0.19	0.19	-	0.01
Total Assets	281.17	353.77	481.72	117.2	18.48

Liabilities

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022
Period Ending	Jun '26 Jun 30, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022
Accounts Payable	2.31	2.73	4.04	1.99	0.71
Accrued Expenses	6.95	10.01	5.99	4.48	4.06
Current Portion of Leases	0.73	0.72	0.7	0.05	0.09
Total Current Liabilities	9.99	13.45	10.74	6.52	4.86
Long-Term Leases	0.23	0.55	1.13	-	0.01
Other Long-Term Liabilities	-	-	-	2.87	6.95
Total Liabilities	10.21	14	11.87	9.39	11.81

Shareholders' Equity

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022
Period Ending	Jun '26 Jun 30, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022
Common Stock	0.05	0.05	0.05	0	0
Additional Paid-In Capital	685.54	673.41	660.6	4.82	1.28
Retained Earnings	-414.52	-334.22	-190.78	-127.97	-107.44
Comprehensive Income & Other	-0.12	0.53	-0.03	0.02	-
Total Common Equity	270.96	339.77	469.85	-123.13	-106.16
Shareholders' Equity	270.96	339.77	469.85	107.81	6.67
Total Liabilities & Equity	281.17	353.77	481.72	117.2	18.48

Additional Metrics

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022
Period Ending	Jun '26 Jun 30, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022
Total Debt	0.95	1.27	1.83	0.05	0.09
Net Cash (Debt)	260.35	340.24	468.62	109.77	16.96
Net Cash Growth	-33.59%	-27.40%	326.93%	547.31%	-
Net Cash Per Share	4.80	6.32	34.25	37.16	6.06
Filing Date Shares Outstanding	54.77	54.42	53.64	2.85	2.8
Total Common Shares Outstanding	54.77	54.24	53.6	2.85	2.8
Working Capital	269.61	338.35	468.42	110.48	13.45
Book Value Per Share	4.95	6.26	8.77	-43.16	-37.91
Tangible Book Value	270.96	339.77	469.85	-123.13	-106.16
Tangible Book Value Per Share	4.95	6.26	8.77	-43.16	-37.91
Machinery	0.82	0.82	0.67	0.2	0.02
Construction In Progress	-	-	-	-	0.04
Leasehold Improvements	0.09	0.09	0.07	0.03	0.02

SEC Filings: 10-K · 10-Q