Upstream Bio, Inc. (UPB)

NASDAQ: UPB · Real-Time Price · USD

6.62

+0.21 (3.28%)

Jul 30, 2026, 3:04 PM EDT - Market open

Upstream Bio Cash Flow Statement

Financials in millions USD. Fiscal year is January - December.

Millions USD. Fiscal year is Jan - Dec.

Operating Activities

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022
Period Ending	Mar '26 Mar 31, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022
Net Income	-156.76	-143.44	-62.81	-20.54	-23.87
Depreciation & Amortization	0.19	0.19	0.09	0.06	0.01
Stock-Based Compensation	12.34	10.33	6	3.43	1.28
Other Adjustments	0.06	-0.94	-4.33	-16.57	0.15
Change in Receivables	-0.48	-0.06	-0.52	0.31	-0.41
Changes in Accounts Payable	-3.01	-1.28	2.02	1.28	0.46
Changes in Accrued Expenses	7.09	4.01	1.51	0.42	4.02
Changes in Other Operating Activities	0.59	-2.09	-1.14	-6.32	-0.66
Operating Cash Flow	-139.96	-133.28	-59.17	-37.93	-19.02
Operating Cash Flow Growth	-	-	-	-	-

Investing Activities

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022
Period Ending	Mar '26 Mar 31, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022
Capital Expenditures	-	-0.17	-0.51	-0.14	-0.08
Purchases of Investments	-134.24	-385.88	-290.61	-128.99	-
Proceeds from Sale of Investments	296.71	292.56	231.64	46.29	-
Investing Cash Flow	162.3	-93.48	-59.49	-82.84	-0.08

Financing Activities

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022
Period Ending	Mar '26 Mar 31, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022
Issuance of Common Stock	2.88	2.48	272.88	0.12	-
Net Common Stock Issued (Repurchased)	2.88	2.48	272.88	0.12	-
Issuance of Preferred Stock	-	-	149.92	129.43	10
Net Preferred Stock Issued (Repurchased)	-	-	149.92	129.43	10
Other Financing Activities	-	-0.03	-3.9	-	-0.04
Financing Cash Flow	3.07	2.44	418.91	129.55	9.96

Net Cash Flow

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022
Period Ending	Mar '26 Mar 31, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022
Net Cash Flow	25.41	-224.31	300.25	8.78	-9.14

Free Cash Flow

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022
Period Ending	Mar '26 Mar 31, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022
Free Cash Flow	-139.96	-133.44	-59.68	-38.07	-19.1
Free Cash Flow Growth	-	-	-	-	-
FCF Margin	-4213.18%	-4675.54%	-2518.27%	-1599.58%	-1576.16%
Free Cash Flow Per Share	-2.59	-2.48	-4.36	-12.89	-6.50
Levered Free Cash Flow	-111.3	-142.78	-74.43	-42.96	-20.12
Unlevered Free Cash Flow	-167.09	-159.69	-75.8	-44.82	-20.16

SEC Filings: 10-K · 10-Q