Upstream Bio Income Statement

Financials in millions USD. Fiscal year is January - December.

Millions USD. Fiscal year is Jan - Dec.

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022
Period Ending	Jun '26 Jun 30, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022
Revenue	3.16	2.85	2.37	2.38	1.21
Revenue Growth	15.97%	20.42%	-0.42%	96.37%	-
Gross Profit	3.16	2.85	2.37	2.38	1.21
Selling, General & Admin	27.34	26.41	17.17	10.7	6.46
Research & Development	145.8	136.81	62.97	31.8	18.66
Operating Expenses	173.14	163.22	80.13	42.49	25.12
Operating Income	-169.98	-160.36	-77.76	-40.11	-23.91
Interest & Investment Income	13.47	16.93	12.12	4.17	0.21
Other Non Operating Income (Expenses)	0.01	-0.02	2.84	15.41	-0.16
Pretax Income	-156.5	-143.44	-62.81	-20.54	-23.87
Net Income	-156.5	-143.44	-62.81	-20.54	-23.87
Preferred Dividends & Other Adjustments	-	-	13.59	17.72	-
Net Income to Common	-156.5	-143.44	-76.4	-38.26	-23.87
Net Income Growth	-	-	-	-	-
Shares Outstanding (Basic)	54	54	14	3	3
Shares Outstanding (Diluted)	54	54	14	3	3
Shares Change	38.95%	293.59%	363.22%	5.49%	-
EPS (Basic)	-2.89	-2.66	-5.58	-12.95	-8.52
EPS (Diluted)	-2.89	-2.66	-5.58	-12.95	-8.52
EPS Growth	-	-	-	-	-

Additional Metrics

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022
Period Ending	Jun '26 Jun 30, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022
Free Cash Flow	-136.46	-133.44	-59.68	-38.07	-19.1
Free Cash Flow Per Share	-2.52	-2.48	-4.36	-12.89	-6.82
Gross Margin	100.00%	100.00%	100.00%	100.00%	100.00%
Operating Margin	-5382.65%	-5618.82%	-3281.18%	-1685.46%	-1972.69%
Profit Margin	-4955.67%	-5026.03%	-3223.42%	-1607.35%	-1969.31%
Free Cash Flow Margin	-4321.15%	-4675.54%	-2518.27%	-1599.58%	-1576.15%
EBITDA	-169.78	-160.17	-77.68	-40.05	-23.9
D&A For EBITDA	0.2	0.19	0.09	0.06	0.01
EBIT	-169.98	-160.36	-77.76	-40.11	-23.91

SEC Filings: 10-K · 10-Q