Upstream Bio, Inc. (UPB)

Upstream Bio Statistics

Total Valuation

Upstream Bio has a market cap or net worth of $600.88 million. The enterprise value is $171.20 million.

Market Cap	600.88M
Enterprise Value	171.20M

Important Dates

The last earnings date was Tuesday, May 6, 2025, before market open.

Earnings Date	May 6, 2025
Ex-Dividend Date	n/a

Share Statistics

Upstream Bio has 53.79 million shares outstanding. The number of shares has increased by 777.19% in one year.

Current Share Class	53.79M
Shares Outstanding	53.79M
Shares Change (YoY)	+777.19%
Shares Change (QoQ)	+17.32%
Owned by Insiders (%)	0.08%
Owned by Institutions (%)	60.00%
Float	31.30M

Valuation Ratios

PE Ratio	n/a
Forward PE	n/a
PS Ratio	128.13
Forward PS	418.23
PB Ratio	1.34
P/TBV Ratio	1.35
P/FCF Ratio	n/a
P/OCF Ratio	n/a
PEG Ratio	n/a

Enterprise Valuation

EV / Earnings	n/a
EV / Sales	74.56
EV / EBITDA	n/a
EV / EBIT	n/a
EV / FCF	n/a

Financial Position

The company has a current ratio of 47.43, with a Debt / Equity ratio of 0.00.

Current Ratio	47.43
Quick Ratio	45.27
Debt / Equity	0.00
Debt / EBITDA	n/a
Debt / FCF	n/a
Interest Coverage	n/a

Financial Efficiency

Return on equity (ROE) is -28.62% and return on invested capital (ROIC) is -21.34%.

Return on Equity (ROE)	-28.62%
Return on Assets (ROA)	n/a
Return on Invested Capital (ROIC)	-21.34%
Return on Capital Employed (ROCE)	-21.22%
Revenue Per Employee	$44,154
Profits Per Employee	-$1.72M
Employee Count	52
Asset Turnover	n/a
Inventory Turnover	n/a

Taxes

Income Tax	n/a
Effective Tax Rate	n/a

Stock Price Statistics

Beta (5Y)	n/a
52-Week Price Change	n/a
50-Day Moving Average	9.11
200-Day Moving Average	n/a
Relative Strength Index (RSI)	63.78
Average Volume (20 Days)	378,323

Short Selling Information

The latest short interest is 3.69 million, so 6.85% of the outstanding shares have been sold short.

Short Interest	3.69M
Short Previous Month	3.75M
Short % of Shares Out	6.85%
Short % of Float	11.77%
Short Ratio (days to cover)	10.79

Income Statement

In the last 12 months, Upstream Bio had revenue of $2.30 million and -$89.66 million in losses. Loss per share was -$3.40.

Revenue	2.30M
Gross Profit	2.30M
Operating Income	-94.76M
Pretax Income	-54.81M
Net Income	-89.66M
EBITDA	-94.65M
EBIT	-94.76M
Loss Per Share	-$3.40

Balance Sheet

The company has $431.38 million in cash and $1.70 million in debt, giving a net cash position of $429.68 million or $7.99 per share.

Cash & Cash Equivalents	431.38M
Total Debt	1.70M
Net Cash	429.68M
Net Cash Per Share	$7.99
Equity (Book Value)	445.61M
Book Value Per Share	8.31
Working Capital	444.22M

Cash Flow

In the last 12 months, operating cash flow was -$82.78 million and capital expenditures -$511,000, giving a free cash flow of -$83.29 million.

Operating Cash Flow	-82.78M
Capital Expenditures	-511,000
Free Cash Flow	-83.29M
FCF Per Share	-$1.55

Margins

Gross Margin	100.00%
Operating Margin	-4,127.35%
Pretax Margin	-3,448.69%
Profit Margin	n/a
EBITDA Margin	n/a
EBIT Margin	n/a
FCF Margin	n/a

Dividends & Yields

Upstream Bio does not appear to pay any dividends at this time.

Dividend Per Share	n/a
Dividend Yield	n/a
Dividend Growth (YoY)	n/a
Years of Dividend Growth	n/a
Payout Ratio	n/a
Buyback Yield	-777.19%
Shareholder Yield	-777.19%
Earnings Yield	-14.92%
FCF Yield	-13.86%

Analyst Forecast

The average price target for Upstream Bio is $56.50, which is 405.82% higher than the current price. The consensus rating is "Strong Buy".

Price Target	$56.50
Price Target Difference	405.82%
Analyst Consensus	Strong Buy
Analyst Count	4
Revenue Growth Forecast (5Y)	n/a
EPS Growth Forecast (5Y)	n/a

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value	n/a
Lynch Upside	n/a
Graham Number	n/a
Graham Upside	n/a

Stock Splits

This stock does not have any record of stock splits.

Last Split Date	n/a
Split Type	n/a
Split Ratio	n/a

Scores

Upstream Bio has an Altman Z-Score of 39.93 and a Piotroski F-Score of 1.

Altman Z-Score	39.93
Piotroski F-Score	1